On the mechanism of isomerization of all-trans-retinol esters to 11-cis-retinol in retinal pigment epithelial cells: 11-Fluoro-all-trans-retinol as substrate/inhibitor in the visual cycle

Bioorganic and Medicinal Chemistry

Volumn 13, Issue 17, 2005, Pages 5189-5194

  Fishkin, Nathan ^a   Yefidoff, Revital ^a   Gollipalli, Deviprasad R ^a   Rando, Robert R ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

11 Fluoro retinol; Isomerohydrolase mechanism; Visual cycle

Indexed keywords

BLOCKING AGENT; CARBON; ENZYME; RETINOL; RETINOL DERIVATIVE; RETINOL ESTER;

ARTICLE; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME METABOLISM; ENZYME SPECIFICITY; ENZYME SYNTHESIS; ESTERIFICATION; ISOMER; ISOMERIZATION; MAMMAL; PIGMENT EPITHELIUM; PROTEIN PROCESSING; PROTEIN SYNTHESIS; VISION;

ESTERS; ISOMERISM; MAGNETIC RESONANCE SPECTROSCOPY; PIGMENT EPITHELIUM OF EYE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; VISION; VITAMIN A;

EID: 22844436225     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.05.001     Document Type: Article

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