Increased αCGRP potency and CGRP-receptor antagonist affinity in isolated hypoxic porcine intramyocardial arteries

British Journal of Pharmacology

Volumn 145, Issue 5, 2005, Pages 646-655

  Hasbak, Philip ^a   Eskesen, Karen ^a   Schifter, Søren ^a   Edvinsson, Lars ^a  

^a GLOSTRUP UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Adrenomedullin; Amylin; Calcitonin like receptor; CGRP; Hyperoxia; Hypoxia; Normoxia; Receptor activity modifying proteins

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 8 (3 CHLOROSTYRYL)CAFFEINE; ADENOSINE; ADENOSINE A2A RECEPTOR ANTAGONIST; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; ADRENOMEDULLIN; ADRENOMEDULLIN RECEPTOR; ALPHA CALCITONIN GENE RELATED PEPTIDE; ALPHA CALCITONIN GENE RELATED PEPTIDE[8-37]; AMYLIN; CALCITONIN GENE RELATED PEPTIDE 1 RECEPTOR; CALCITONIN GENE RELATED PEPTIDE RECEPTOR; CALCITONIN GENE RELATED PEPTIDE RECEPTOR ANTAGONIST; CALCITONIN GENE RELATED PEPTIDE[8-37]; CYCLIC AMP; ENDOTHELIUM DERIVED RELAXING FACTOR; ENZYME INHIBITOR; GLIBENCLAMIDE; INDOMETACIN; MESSENGER RNA; N(G) METHYLARGININE; NITROPRUSSIDE SODIUM; PEPTIDASE INHIBITOR; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; RECEPTOR ACTIVITY MODIFYING PROTEIN; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; VASODILATOR AGENT; ABC TRANSPORTER; CALCITONIN GENE RELATED PEPTIDE; INWARDLY RECTIFYING POTASSIUM CHANNEL; NITRIC OXIDE SYNTHASE; PROSTAGLANDIN; PROTEINASE INHIBITOR; UK ATP 1 POTASSIUM CHANNEL; UK-ATP-1 POTASSIUM CHANNEL;

ANIMAL TISSUE; ARTERY ENDOTHELIUM; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CORONARY ARTERY; CORONARY ARTERY DILATATION; DISSOCIATION CONSTANT; DRUG EFFECT; DRUG RECEPTOR BINDING; HYPOXIA; IN VITRO STUDY; NONHUMAN; PKB; PRIORITY JOURNAL; SCHILD PLOT; SWINE; ANIMAL; ARTERY; DRUG ANTAGONISM; HEART MUSCLE; METABOLISM; MUSCLE CONTRACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VASCULAR SMOOTH MUSCLE; VASODILATATION;

ADENOSINE; ANIMALS; ARTERIES; ATP-BINDING CASSETTE TRANSPORTERS; CALCITONIN GENE-RELATED PEPTIDE; CYCLIC AMP; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; MYOCARDIUM; NITRIC OXIDE SYNTHASE; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROSTAGLANDINS; PROTEASE INHIBITORS; RECEPTORS, CALCITONIN GENE-RELATED PEPTIDE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SWINE; VASODILATION; VASODILATOR AGENTS;

EID: 22744443867     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706232     Document Type: Article

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