Differential desensitization of homozygous haplotypes of the β2-adrenergic receptor in lymphocytes

American Journal of Respiratory and Critical Care Medicine

Volumn 172, Issue 3, 2005, Pages 322-328

  Oostendorp, Jaap ^b   Postma, Dirkje S ^b   Volders, Haukeline ^b   Jongepier, Hajo ^b   Kauffman, Henk F ^b   Boezen, H Marike ^b   Meyers, Deborah A ^b   Bleecker, Eugene R ^b   Nelemans, S Adriaan ^b   Zaagsma, Johan ^b   Meurs, Herman ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b NONE

Author keywords

5 leader cistron; cAMP; Cytokine production; Sequestration and downregulation; Single nucleotide polymorphism

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; CYCLIC AMP; ISOPRENALINE;

ADULT; AMINO ACID SUBSTITUTION; ARTICLE; CLINICAL ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DESENSITIZATION; DOWN REGULATION; FAMILY STUDY; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENETIC SUSCEPTIBILITY; HAPLOTYPE; HOMOZYGOSITY; HUMAN; LYMPHOCYTE; MALE; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY MECHANISM; STATISTICAL SIGNIFICANCE;

ADULT; ARGININE; CYCLIC AMP; CYSTEINE; CYTOKINES; DESENSITIZATION, IMMUNOLOGIC; DOWN-REGULATION; FEMALE; GLUTAMIC ACID; GLUTAMINE; GLYCINE; HAPLOTYPES; HOMOZYGOTE; HUMANS; LYMPHOCYTES; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, ADRENERGIC, BETA-2; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 22644439247     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/rccm.200409-1162OC     Document Type: Article

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