Subtype C is associated with increased vaginal shedding of HIV-1

Journal of Infectious Diseases

Volumn 192, Issue 3, 2005, Pages 492-496

  John Stewart, Grace C ^a,c   Nduati, Ruth W ^c   Rousseau, Christine M ^b   Mbori Ngacha, Dorothy A ^c   Richardson, Barbra A ^a,b   Rainwater, Stephanie ^b   Panteleeff, Dana D ^b   Overbaugh, Julie ^b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

^c UNIVERSITY OF NAIROBI   (Kenya)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; VIRUS RNA;

ADULT; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION RISK; KENYA; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; VAGINA MUCOSA; VERTICAL TRANSMISSION; VIRUS LOAD; VIRUS SHEDDING; VIRUS STRAIN;

COLOSTRUM; DISEASE TRANSMISSION, VERTICAL; FEMALE; HIV SEROPOSITIVITY; HIV-1; HUMANS; INFANT, NEWBORN; PHYLOGENY; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; RNA, VIRAL; VAGINA; VIRAL LOAD; VIRUS SHEDDING;

EID: 22544479096     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/431514     Document Type: Article

References (15)

1. Kaleebu P, French N, Mahe C, et al. Effect of human immunodeficiency virus (HIV) type 1 envelope subtypes A and D on disease progression in a large cohort of HIV-1-positive persons in Uganda. J Infect Dis 2002; 185:1244-50.
2. Kanki PJ, Hamel DJ, Sankale JL, et al. Human immunodeficiency virus type 1 subtypes differ in disease progression. J Infect Dis 1999; 179: 68-73.
3. Kunanusont C, Foy HM, Kreiss JK, et al. HIV-1 subtypes and male-to-female transmission in Thailand. Lancet 1995; 345:1078-83.
4. Eshleman SH, Becker-Pergola G, Desyve M, Guay LA, et al. Impact of human immunodeficiency virus type 1 (HIV-1) subtype on women receiving single-dose nevirapine prophylaxis to prevent HIV-1 transmission (HIV Network for Prevention Trials 012 Study). J Infect Dis 2001; 184:914-7.
5. Blackard JT, Renjifo B, Fawzi W, et al. HIV-1 LTR subtype and perinatal transmission. Virology 2001; 287:261-5.
6. Nduati R, John G, Mbori-Ngacha D, et al. Effect of breastfeeding and formula feeding on transmission of HIV-1: a randomized clinical trial. JAMA 2000; 283:1167-74.
7. John GC, Nduati RW, Mbori-Ngacha DA, et al. Correlates of mother-to-child human immunodeficiency virus type 1 (HIV-1) transmission: association with maternal plasma HIV-1 RNA load, genital HIV-1 DNA shedding, and breast infections. J Infect Dis 2001; 183:206-12.
8. Panteleeff DD, Emery S, Richardson B, et al. Validation of the performance of the Gen-Probe HIV-1 viral load assay for genital swabs and breastmilk samples. J Clin Microbiol 2002; 40:3929-37.
9. Emery S, Bodrug S, Richardson B, et al. Evaluation of performance of the Gen-Probe human immunodeficiency virus type 1 viral load assay using primary subtype A, C, and D isolates from Kenya. J Clin Microbiol 2000; 38:2688-95.
10. Rousseau CM, Nduati RW, Richardson BA, et al. Longitudinal analysis of human immunodeficiency virus type 1 RNA in breast milk and of its relationship to infant infection and maternal disease. J Infect Dis 2003; 187:741-7.
11. Neilson JR, John GC, Carr JK, et al. Subtypes of human immunodeficiency virus type 1 and disease stage among women in Nairobi, Kenya. J Virol 1999; 73:4393-403.
12. Panteleeff DD, John G, Nduati R, et al. Rapid method for screening dried blood samples on filter paper for human immunodeficiency virus type 1 DNA. J Clin Microbiol 1999; 37:350-3.
13. Burns CC, Gleason LM, Mozaffarian A, Giachetti C, Carr JK, Overbaugh J. Sequence variability of the integrase protein from a diverse collection of HIV type 1 isolates representing several subtypes. AIDS Res Hum Retroviruses 2002; 18:1031-41.
14. Ghys PD, Fransen K, Diallo MO, et al. The associations between cervicovaginal HIV shedding, sexually transmitted diseases and immunosuppression in female sex workers in Abidjan, Cote d'Ivoire. AIDS 1997; 11:F85-93.
15. Adjorlolo-Johnson G, De Cock K, Ekpini E, et al. Prospective comparison of mother-to-child transmission of HIV-1 and HIV-2 in Abidjan, Ivory Coast. JAMA 1994; 272:462-6.