Surfactant-induced depletion of ceramides and other intercellular lipids: Implication for the mechanism leading to dehydration of the stratum corneum

Exogenous Dermatology

Volumn 3, Issue 2, 2004, Pages 81-98

  Imokawa, Genji ^a,b  

^a Kao Biological Science Laboratories   (Japan)

^b Kao Biological Science Laboratories   (Japan)

Author keywords

Amino acids; Bound water; Ceramides; Dehydration; Intercellular lipids; Stratum corneum; Surfactant; Water holding function

Indexed keywords

ACETONE; AMINO ACID; CERAMIDE; ETHER; LIPID; MONOACYLGLYCEROL; WATER;

ARTICLE; ATOPY; CORRELATION ANALYSIS; DEHYDRATION; DIFFERENTIAL SCANNING CALORIMETRY; DRY SKIN; HYDRATION; MOLECULAR INTERACTION; PATHOLOGY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SKIN DISEASE; SKIN SENSATION; STRATUM CORNEUM; WATER RETENTION; X RAY DIFFRACTION;

EID: 22544478779     PISSN: 14244616     EISSN: None     Source Type: Journal    
DOI: 10.1159/000086158     Document Type: Article

References (27)

1. Jacobi OT: About the mechanisms of moisture regulation in the horny layer of the skin. Proc Sci Sect Good Assoc 1959;31:22-24.
2. Imokawa G, Hattori M: A possible function of structural lipid in the water-holding properties of the stratum corneum. J Invest Dermatol 1985;84:282-284.
3. Imokawa G: Stratum corneum moisturizing effect and intercellular lipids. Fragrance J 1987;15:35-41.
4. Imokawa G: Ceramide, Gendai Hifukagaku Taikei. Tokyo, Nakayama Publishing Corp, 2002, pp 34-42.
5. Imokawa G: Properties and function of the stratum corneum lipids and its measurement. Rinshouhifuka 1990;44:583-588.
6. Imokawa G, Akasaki S, Kuno O, Zama M, Kawai M, Minematsu Y, Hattori M, Yoshizuka N, Kawamata A, Yano S, Takaishi N: Function of lipids on human skin. J Dis Sci Tech 1989;10:617-641.
7. Imokawa G: Water and the stratum corneum; in Elsner P, Berardesca E, Maibach HI (eds): Bioengineering of the Skin: In vitro and in vivo Models. Boca Raton, CRC Press, 1993, vol 1, chapt 3, pp 23-47.
8. Imokawa G, Akasaki S, Hattori M, Yoshizuka N: Selective recovery of deranged water-holding properties by stratum corneum lipids. J Invest Dermatol 1986;87:758-761.
9. Akasaki S, Minematsu Y, Yoshizuka N, Imokawa G: The role of intercellular lipids in the water-holding properties of the stratum corneum: Recovery effect on experimentally induced dry skin. Jpn J Dermatol 1988;98:40-51.
10. Imokawa G: Role of stratum corneum components in their moisturizing function. Fragrance J 2000;17:27-39.
11. Imokawa G, Kuno H, Kawai M: Stratum corneum lipids serve as a bound-water modulator. J Invest Dermatol 1991;96:845-851.
12. Imokawa G: Atopic dermatitis: Dry skin mechanism. Jpn Pediatr Dermatol 1997;16:87-99.
13. Pieper J, Charalambopoulou G, Steriotis T, Vasenkov S, Desmedt A, Lechner RE: Water diffusion in fully hydrated porcine stratum corneum. Chem Phys 2003;292:465-476.
14. Bouwstra JA, Gooris GS, van der Spek JA, Bras W: Structural investigations of human stratum corneum by small-angle X-ray scattering. J Invest Dermatol 1991;97:1005-1012.
15. Ohta N, Ban S, Tanaka H, Nakata S, Hatta I: Swelling of intercellular lipid lamellar structure with short repeat distance in hairless mouse stratum corneum as studied by X-ray diffraction. Chem Phys Lipids 2003;123:1-8.
16. Imokawa G: Skin moisturizers: Development and clinical use of ceramides; in Loden M (ed): Dry Skin and Moisturizers. Boca Raton, CRC Press, 1999, pp 269-299.
17. Imokawa G: Moisturizers used in dermatology fields. J Clin Dermatol 1998;56:87-96.
18. Imokawa G: Structure and function of intercellular lipids in the stratum corneum. Yukagaku 1995;44:751-766.
19. 13C-nuclear magnetic resonance spectroscopy. J Invest Dermatol 1995;104:806-812.
20. Nakagawa N, Sakai S, Matsumoto M, Yamada K, Nagano M, Yuki T, Sumida Y, Uchiwa H: Relationship between NMF (lactate and potassium) content and the physical properties of the stratum corneum in healthy subjects. J Invest Dermatol 2004;122:755-763.
21. Kawai M, Imokawa G: The induction of skin tightness by surfactants. J Soc Cosmet Chem 1984;35:147-156.
22. Imokawa G, Mishima Y: Adsorption of surfactants onto human keratin layer in vivo. Contact Dermatitis 1979;5:357-366.
23. Imokawa G, Akasaki S, Minematsu Y, Kawai M: Importance of intercellular lipids in water-retention properties of the stratum corneum: Induction and recovery study of surfactant dry skin. Arch Dermatol Res 1989;281:45-51.
24. Imokawa G: Surfactant mildness; in Rhein LD, Rieger MM (eds): Surfactants in Cosmetics. New York, Dekker, 1995, pp 23-145.
25. Kondo T, Okuda M, Imokawa G: The preventive effect of monoglyceride on the skin roughness induced by dish detergent. Jpn J Dermatol 1995;105:1217-1225.
26. Imokawa G, Akasaki S, Kawamata A, Yano S, Takaishi N: Water-retaining function in the stratum corneum and its recovery properties by synthetic pseudo-ceramides. J Soc Cosmet Chem 1989;40:273-285.
27. Imokawa G: Ceramides as natural moisturizing factors and their efficacy in dry skin; in Leyden JJ, Rawlings AV (eds): Skin Moisturization. New York, Dekker, 2002, pp 267-302.