Effects of galanin-like peptide (GALP) on locomotion, reproduction, and body weight in female and male mice

Hormones and Behavior

Volumn 48, Issue 2, 2005, Pages 141-151

  Kauffman, Alexander S ^a   Buenzle, Jennifer ^a   Fraley, Gregory S ^b   Rissman, Emilie F ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b HOPE COLLEGE   (United States)

Author keywords

Coordination; Energy balance; Exploration; Gonadotropin releasing hormone; Luteinizing hormone; Motor control; Sexual behavior

Indexed keywords

ESTRADIOL BENZOATE; GALANIN LIKE PEPTIDE; GONADORELIN; GONADORELIN RECEPTOR; ITURELIX; PROGESTERONE; PROTEIN FOS;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; CASTRATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOSE RESPONSE; DRUG INFUSION; FEEDING BEHAVIOR; FEMALE; FOOD INTAKE; GONADORELIN RELEASE; HORMONE ACTION; HORMONE INHIBITION; LIBIDO; LOCOMOTION; LORDOSIS; MALE; MOTOR COORDINATION; MOUSE; NONHUMAN; OPEN FIELD BEHAVIOR; OVARIECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSYCHOSEXUAL DEVELOPMENT; ROTAROD TEST; SEX DIFFERENCE; SEXUAL BEHAVIOR; SEXUAL DYSFUNCTION; SPECIES COMPARISON; WEIGHT REDUCTION;

ANIMALS; BODY WEIGHT; ENERGY METABOLISM; FEMALE; GALANIN-LIKE PEPTIDE; GONADOTROPIN-RELEASING HORMONE; INJECTIONS, INTRAVENTRICULAR; LUTEINIZING HORMONE; MALE; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; MUSCULOSKELETAL EQUILIBRIUM; OVARIECTOMY; REPRODUCTION; SEXUAL BEHAVIOR, ANIMAL; STEREOTAXIC TECHNIQUES;

EID: 22544471537     PISSN: 0018506X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yhbeh.2005.01.010     Document Type: Article

References (65)

1. A. Agmo, R.G. Paredes, L. Sierra, and I. Garces The inhibitory effects on sexual behavior and ambulatory activity of the mixed GABAA/GABAB agonist progabide are differentially blocked by GABA receptor antagonists Psychopharmacology (Berl) 129 1 1997 27 34
2. E.M. Apostolakis, J. Garai, C. Fox, C.L. Smith, S.J. Watson, J.H. Clark, and B.W. O'Malley Dopaminergic regulation of progesterone receptors: brain D5 dopamine receptors mediate induction of lordosis by D1-like agonists in rats J. Neurosci. 16 16 1996 4823 4834
3. J.H. Baik, R. Picetti, A. Saiardi, G. Thiriet, A. Dierich, A. Depaulis, M. Le Meur, and E. Borrelli Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptors Nature 377 6548 1995 424 428
4. A. Benelli, R. Arletti, A. Bertolini, B. Menozzi, R. Basaglia, and R. Poggioli Galantide stimulates sexual behaviour in male rats Eur. J. Pharmacol. 260 2-3 1994 279 282
5. G.J. Bloch, P.C. Butler, J.G. Kohlert, and D.A. Bloch Microinjection of galanin into the medial preoptic nucleus facilitates copulatory behavior in the male rat Physiol. Behav. 54 4 1993 615 624
6. G.J. Bloch, P.C. Butler, and J.G. Kohlert Galanin microinjected into the medial preoptic nucleus facilitates female- and male-typical sexual behaviors in the female rat Physiol. Behav. 59 6 1996 1147 1154
7. A.R. Caggiula, J.G. Herndon Jr., R. Scanlon, D. Greenstone, W. Bradshaw, and D. Sharp Dissociation of active from immobility components of sexual behavior in female rats by central 6-hydroxydopamine: implications for CA involvement in sexual behavior and sensorimotor responsiveness Brain Res. 172 3 1979 505 520
8. D. Centonze, C. Grande, E. Saulle, A.B. Martin, P. Gubellini, N. Pavon, A. Pisani, G. Bernardi, R. Moratalla, and P. Calabresi Distinct roles of D1 and D5 dopamine receptors in motor activity and striatal synaptic plasticity J. Neurosci. 23 24 2003 8506 8512
9. J. Chan, S. Ogawa, and D.W. Pfaff Reproduction-related behaviors of Swiss-Webster female mice living in a cold environment Proc. Natl. Acad. Sci. U. S. A. 98 2 2001 700 704
10. M.A. Charles, and M.Y. McGinnis Effects of LY163502, a D2 dopaminergic agonist, on the sexual behavior of male rats Pharmacol. Biochem. Behav. 43 4 1992 1087 1092
11. R.D. Cone, M.A. Cowley, A.A. Butler, W. Fan, D.L. Marks, and M.J. Low The arcuate nucleus as a conduit for diverse signals relevant to energy homeostasis Int. J. Obes. Relat. Metab. Disord. 25 Suppl 5 2001 S63 S67
12. M.J. Cunningham Galanin-like peptide as a link between metabolism and reproduction J. Neuroendocrinol. 16 8 2004 717 723
13. M.J. Cunningham, J.M. Scarlett, and R.A. Steiner Cloning and distribution of galanin-like peptide mRNA in the hypothalamus and pituitary of the macaque Endocrinology 143 3 2002 755 763
14. M.J. Cunningham, M. Shahab, K.L. Grove, J.M. Scarlett, T.M. Plant, J.L. Cameron, M.S. Smith, D.K. Clifton, and R.A. Steiner Galanin-like peptide as a possible link between metabolism and reproduction in the macaque J. Clin. Endocrinol. Metab. 89 4 2004 1760 1766
15. E. Ellingsen, and A. Agmo Sexual-incentive motivation and paced sexual behavior in female rats after treatment with drugs modifying dopaminergic neurotransmission Pharmacol. Biochem. Behav. 77 3 2004 431 445
16. E. Ericson, and S. Ahlenius Suggestive evidence for inhibitory effects of galanin on mesolimbic dopaminergic neurotransmission Brain Res. 822 1-2 1999 200 209
17. G.S. Fraley, I. Shimada, J.W. Baumgartner, D.K. Clifton, and R.A. Steiner Differential patterns of Fos induction in the hypothalamus of the rat following central injections of galanin-like peptide and galanin Endocrinology 144 4 2003 1143 1146
18. G.S. Fraley, S.E. Thomas-Smith, B.V. Acohido, R.A. Steiner, and D.K. Clifton Stimulation of sexual behavior in the male rat by galanin-like peptide (GALP) Horm. Behav. 46 5 2004 551 557
19. C.A. Frye, and J.M. Vongher GABA(A), D1, and D5, but not progestin receptor, antagonist and anti-sense oligonucleotide infusions to the ventral tegmental area of cycling rats and hamsters attenuate lordosis Behav. Brain Res. 103 1 1999 23 34
20. C.A. Frye, A.A. Walf, and K. Sumida Progestins' actions in the VTA to facilitate lordosis involve dopamine-like type 1 and 2 receptors Pharmacol. Biochem. Behav. 78 3 2004 405 418
21. M.L. Gottsch, D.K. Clifton, and R.A. Steiner Galanin-like peptide as a link in the integration of metabolism and reproduction Trends Endocrinol. Metab. 15 5 2004 215 221
22. R. Hamburger-Bar, and H. Rigter Apomorphine: facilitation of sexual behaviour in female rats Eur. J. Pharmacol. 32 02 1975 357 360
23. K.R. Hansen, S.M. Krasnow, M.A. Nolan, G.S. Fraley, J.W. Baumgartner, D.K. Clifton, and R.A. Steiner Activation of the sympathetic nervous system by galanin-like peptide-a possible link between leptin and metabolism Endocrinology 144 11 2003 4709 4717
24. J.G. Hohmann, A. Jureus, D.N. Teklemichael, A.M. Matsumoto, D.K. Clifton, and R.A. Steiner Distribution and regulation of galanin receptor 1 messenger RNA in the forebrain of wild type and galanin-transgenic mice Neuroscience 117 1 2003 105 117
25. E.M. Hull, D. Bitran, E.A. Pehek, R.K. Warner, L.C. Band, and G.M. Holmes Dopaminergic control of male sex behavior in rats: effects of an intracerebrally-infused agonist Brain Res. 370 1 1986 73 81
26. B.J. Jones, and D.J. Roberts The quantitative measurement of motor inco-ordination in naive mice using an acelerating rotarod J. Pharm. Pharmacol. 20 4 1968 302 304
27. S.R.F. Jungnickel, and A.L. Gundlach [125I]-Galanin binding in brain of wildtype, and galanin- and GALR1-knockout mice: strain and species differences in GALR1 density and distribution Neuroscience 131 2005 407 421
28. A. Jureus, M.J. Cunningham, M.E. McClain, D.K. Clifton, and R.A. Steiner Galanin-like peptide (GALP) is a target for regulation by leptin in the hypothalamus of the rat Endocrinology 141 7 2000 2703 2706
29. A. Jureus, M.J. Cunningham, D. Li, L.L. Johnson, S.M. Krasnow, D.N. Teklemichael, D.K. Clifton, and R.A. Steiner Distribution and regulation of galanin-like peptide (GALP) in the hypothalamus of the mouse Endocrinology 142 12 2001 5140 5144
30. A.S. Kauffman, and E.F. Rissman A critical role for the evolutionarily conserved gonadotropin-releasing hormone II: mediation of energy status and female sexual behavior Endocrinology 145 8 2004 3639 3646
31. N.C. Kerr, F.E. Holmes, and D. Wynick Galanin-like peptide (GALP) is expressed in rat hypothalamus and pituitary, but not in DRG NeuroReport 11 17 2000 3909 3913
32. S.M. Krasnow, G.S. Fraley, S.M. Schuh, J.W. Baumgartner, D.K. Clifton, and R.A. Steiner A role for galanin-like peptide in the integration of feeding, body weight regulation, and reproduction in the mouse Endocrinology 144 3 2003 813 822
33. S.M. Krasnow, J.G. Hohmann, A. Gragerov, D.K. Clifton, and R.A. Steiner Analysis of the contribution of galanin receptors 1 and 2 to the central actions of galanin-like peptide Neuroendocrinology 79 5 2004 268 277
34. Kudwa, A.E., Dominguez-Salazar, E., Cabrera, D.M., Sibley, D.R., and Rissman, E.F., in press. Dopamine D5 receptor modulates male and female sexual behavior in mice. Psychopharmacology (Berl).
35. J.A. Larm, and A.L. Gundlach Galanin-like peptide (GALP) mRNA expression is restricted to arcuate nucleus of hypothalamus in adult male rat brain Neuroendocrinology 72 2 2000 67 71
36. J.A. Larm, P.J. Shen, and A.L. Gundlach Differential galanin receptor-1 and galanin expression by 5-HT neurons in dorsal raphe nucleus of rat and mouse: evidence for species-dependent modulation of serotonin transmission Eur. J. Neurosci. 17 3 2003 481 493
37. C.B. Lawrence, F.M. Baudoin, and S.M. Luckman Centrally administered galanin-like peptide modifies food intake in the rat: a comparison with galanin J. Neuroendocrinol. 14 11 2002 853 860
38. S.K. Mani, J.M. Allen, J.P. Lydon, B. Mulac-Jericevic, J.D. Blaustein, F.J. DeMayo, O. Conneely, and B.W. O'Malley Dopamine requires the unoccupied progesterone receptor to induce sexual behavior in mice Mol. Endocrinol. 10 12 1996 1728 1737
39. H. Matsumoto, J. Noguchi, Y. Takatsu, Y. Horikoshi, S. Kumano, T. Ohtaki, C. Kitada, T. Itoh, H. Onda, O. Nishimura, and M. Fujino Stimulation effect of galanin-like peptide (GALP) on luteinizing hormone-releasing hormone-mediated luteinizing hormone (LH) secretion in male rats Endocrinology 142 8 2001 3693 3696
40. Y. Matsumoto, T. Watanabe, Y. Adachi, T. Itoh, T. Ohtaki, H. Onda, T. Kurokawa, O. Nishimura, and M. Fujino Galanin-like peptide stimulates food intake in the rat Neurosci. Lett. 322 1 2002 67 69
41. J.E. McMinn, R.J. Seeley, C.W. Wilkinson, P.J. Havel, S.C. Woods, and M.W. Schwartz NPY-induced overfeeding suppresses hypothalamic NPY mRNA expression: potential roles of plasma insulin and leptin Regul. Pept. 75-76 1998 425 431
42. J.E. McMinn, D.G. Baskin, and M.W. Schwartz Neuroendocrine mechanisms regulating food intake and body weight Obes. Rev. 1 1 2000 37 46
43. M.E. Meyer Effects of intraaccumbens dopamine agonist SK and F38393 and antagonist SCH23390 on locomotor activities in rats Pharmacol. Biochem. Behav. 45 4 1993 843 847
44. M.E. Meyer, G.A. Cottrell, C. Van Hartesveldt, and T.J. Potter Effects of dopamine D1 antagonists SCH23390 and SK and F83566 on locomotor activities in rats Pharmacol. Biochem. Behav. 44 2 1993 429 432
45. M.J. Millan, L. Seguin, A. Gobert, D. Cussac, and M. Brocco The role of dopamine D3 compared with D2 receptors in the control of locomotor activity: a combined behavioural and neurochemical analysis with novel, selective antagonists in rats Psychopharmacology (Berl) 174 3 2004 341 357
46. D.T. Modianos, and D.W. Pfaff Brain stem and cerebellar lesions in female rats: I. Tests of posture and movement Brain Res. 106 1 1976 31 46
47. D.T. Modianos, and D.W. Pfaff Brain stem and cerebellar lesions in female rats. II. Lordosis reflex Brain Res. 106 1 1976 47 56
48. T. Ohtaki, S. Kumano, Y. Ishibashi, K. Ogi, H. Matsui, M. Harada, C. Kitada, T. Kurokawa, H. Onda, and M. Fujino Isolation and cDNA cloning of a novel galanin-like peptide (GALP) from porcine hypothalamus J. Biol. Chem. 274 52 1999 37041 37045
49. R.G. Paredes Medial preoptic area/anterior hypothalamus and sexual motivation Scand. J. Psychol. 44 3 2003 203 212
50. J.G. Pfaus, and A.G. Phillips Role of dopamine in anticipatory and consummatory aspects of sexual behavior in the male rat Behav. Neurosci. 105 5 1991 727 743
51. R. Picetti, A. Saiardi, T. Abdel Samad, Y. Bozzi, J.H. Baik, and E. Borrelli Dopamine D2 receptors in signal transduction and behavior Crit. Rev. Neurobiol. 11 2-3 1997 121 142
52. R. Poggioli, E. Rasori, and A. Bertolini Galanin inhibits sexual behavior in male rats Eur. J. Pharmacol. 213 1 1992 87 90
53. A. Ragnauth, A. Schuller, M. Morgan, J. Chan, S. Ogawa, J. Pintar, R.J. Bodnar, and D.W. Pfaff Female preproenkephalin-knockout mice display altered emotional responses Proc. Natl. Acad. Sci. U. S. A. 98 4 2001 1958 1963
54. N.R. Rustay, D. Wahlsten, and J.C. Crabbe Influence of task parameters on rotarod performance and sensitivity to ethanol in mice Behav. Brain Res. 141 2 2003 237 249
55. A. Sahu, B. Xu, and S.P. Kalra Role of galanin in stimulation of pituitary luteinizing hormone secretion as revealed by a specific receptor antagonist, galantide Endocrinology 134 2 1994 529 536
56. Y. Sakuma Estrogen-induced changes in the neural impulse flow from the female rat preoptic region Horm. Behav. 28 4 1994 438 444
57. A. Seth, S. Stanley, W. Dhillo, K. Murphy, M. Ghatei, and S. Bloom Effects of galanin-like peptide on food intake and the hypothalamo-pituitary- thyroid axis Neuroendocrinology 77 2 2003 125 131
58. A. Seth, S. Stanley, P. Jethwa, J. Gardiner, M. Ghatei, and S. Bloom Galanin-like peptide stimulates the release of gonadotropin-releasing hormone in vitro and may mediate the effects of leptin on the hypothalamo-pituitary- gonadal axis Endocrinology 145 2 2004 743 750
59. R.B. Simerly, and L.W. Swanson Projections of the medial preoptic nucleus: a Phaseolus vulgaris leucoagglutinin anterograde tract-tracing study in the rat J. Comp. Neurol. 270 2 1988 209 242
60. R.L. Smith, D.G. Webster, C. Van Hartesveldt, and M.E. Meyer Effects of estrus, estrogen-progesterone priming, and vaginal stimulation on tonic immobility, dorsal immobility, and lordosis in the female rat Physiol. Behav. 35 4 1985 577 581
61. L.W. Swanson, G.J. Mogenson, R.B. Simerly, and M. Wu Anatomical and electrophysiological evidence for a projection from the medial preoptic area to the 'mesencephalic and subthalamic locomotor regions' in the rat Brain Res. 405 1 1987 108 122
62. Y. Takatsu, H. Matsumoto, T. Ohtaki, S. Kumano, C. Kitada, H. Onda, O. Nishimura, and M. Fujino Distribution of galanin-like peptide in the rat brain Endocrinology 142 4 2001 1626 1634
63. E. Tirelli, and P. Terry Biphasic locomotor effects of the dopamine D1 agonist SKF 38393 and their attenuation in non-habituated mice Psychopharmacology (Berl) 110 1-2 1993 69 75
64. S.R. Wersinger, and E.F. Rissman Oestrogen receptor alpha is essential for female-directed chemo-investigatory behaviour but is not required for the pheromone-induced luteinizing hormone surge in male mice J. Neuroendocrinol. 12 2 2000 103 110
65. F.P. Zemlan, and D.W. Pfaff Lordosis after cerebellar damage in female rats Horm. Behav. 6 1 1975 27 33