Phosphorylation of the yeast choline kinase by protein kinase C: Identification of Ser25 and Ser30 as major sites of phosphorylation

Journal of Biological Chemistry

Volumn 280, Issue 28, 2005, Pages 26105-26112

  Choi, Mal Gi ^a   Kurnov, Vladlen ^a   Kersting, Michael C ^a   Sreenivas, Avula ^a   Carman, George M ^a,b  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CORRELATION METHODS; PHOSPHORS; SYNTHESIS (CHEMICAL); YEAST;

PHOSPHATIDYLCHOLINE SYNTHESIS; PHOSPHORYLATION; PROTEIN KINASE; YEAST CHOLINE KINASE;

ENZYMES;

ADENOSINE TRIPHOSPHATE; ALANINE; CHOLINE KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE; MUTANT PROTEIN; PROTEIN KINASE C; SERINE; SERYLARGINYLSERYLSERYLSERYLGLUTAMINYLARGINYLARGINYLHISTIDYLSERINE; SERYLGLUTAMINYLARGINYLARGINYLHISTIDYLLEUCYLTHREONYLARGINYLGLUTAMINE; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; KENNEDY PATHWAY; MUTATION; NONHUMAN; PEPTIDE MAPPING; PHOSPHOLIPID SYNTHESIS; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE CK11; YEAST;

ADENOSINE TRIPHOSPHATE; ALANINE; ALLELES; AMINO ACID MOTIFS; BINDING SITES; BIOCHEMISTRY; CHOLINE KINASE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; HYDROLYSIS; IMMUNOBLOTTING; IMMUNOGLOBULIN G; IMMUNOPRECIPITATION; KINETICS; MODELS, BIOLOGICAL; MUTATION; PEPTIDE MAPPING; PEPTIDES; PHOSPHATIDYLCHOLINES; PHOSPHORYLATION; PLASMIDS; POLYMERASE CHAIN REACTION; PROTEIN BINDING; PROTEIN KINASE C; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE; SERINE; SUBSTRATE SPECIFICITY; TIME FACTORS;

SACCHAROMYCES CEREVISIAE;

EID: 22544467022     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M503551200     Document Type: Article

References (91)

1. Vance, D. E. (1996) in Biochemistry of Lipids, Lipoproteins and Membranes (Vance, D. E., and Vance, J., eds) pp. 153-181, Elsevier Science Publishers B. V., Amsterdam
2. Kent, C. (1997) Biochim. Biophys. Acta 1348, 79-90
3. Kent, C., and Carman, G. M. (1999) Trends Biochem. Sci. 24, 146-150
4. Carman, G. M., and Henry, S. A. (1999) Prog. Lipid Res. 38, 361-399
5. Spector, A. A., and Yorek, M. A. (1985) J. Lipid Res. 26, 1015-1035
6. Rooney, S. A. (1985) Am. Rev. Respir. Dis. 131, 439-460
7. Vance, J. E., and Vance, D. E. (1985) Can. J. Biochem. Cell Biol. 63, 870-881
8. Agellon, L. B., Walkey, C. J., Vance, D. E., Kuipers, F., and Verkade, H. J. (1999) Hepatology 30, 725-729
9. Cui, Z., Houweling, M., Chen, M. H., Record, M., Chap, H., Vance, D. E., and Terce, F. (1996) J. Biol. Chem. 271, 14668-14671
10. Anthony, M. L., Zhao, M., and Brindle, K. M. (1999) J. Biol. Chem. 274, 19686-19692
11. Wright, M. M., Henneberry, A. L., Lagace, T. A., Ridgway, N. D., and McMaster, C. R. (2001) J. Biol. Chem. 276, 25254-25261
12. Cui, Z., and Houweling, M. (2002) Biochim. Biophys. Acta 1585, 87-96
13. Ratnam, S., and Kent, C. (1995) Arch. Biochem. Biophys. 323, 313-322
14. Aboagye, E. O., and Bhujwalla, Z. M. (1999) Cancer Res. 59, 80-84
15. Street, J. C., Szwergold, B. S., Matei, C., Kappler, F., Mahmood, U., Brown, T. R., and Koutcher, J. A. (1997) Magn. Reson. Med. 38, 769-775
16. Paltauf, F., Kohlwein, S. D., and Henry, S. A. (1992) in The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression (Jones, E. W., Pringle, J. R., and Broach, J. R., eds) pp. 415-500, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
17. McMaster, C. R., and Bell, R. M. (1994) J. Biol. Chem. 269, 14776-14783
18. Patton-Vogt, J. L., Griac, P., Sreenivas, A., Bruno, V., Dowd, S., Swede, M. J., and Henry, S. A. (1997) J. Biol. Chem. 272, 20873-20883
19. Xie, Z. G., Fang, M., Rivas, M. P., Faulkner, A. J., Sternweis, P. C., Engebrecht, J., and Bankaitis, V. A. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 12346-12351
20. Morash, S. C., McMaster, C. R., Hjelmstad, R. H., and Bell, R. M. (1994) J. Biol. Chem. 269, 28769-28776
21. McGee, T. P., Skinner, H. B., Whitters, E. A., Henry, S. A., and Bankaitis, V. A. (1994) J. Cell Biol. 124, 273-287
22. McMaster, C. R., and Bell, R. M. (1994) J. Biol. Chem. 269, 28010-28016
23. McDonough, V. M., Buxeda, R. J., Bruno, M. E. C., Ozier-Kalogeropoulos, O., Adeline, M.-T., McMaster, C. R., Bell, R. M., and Carman, G. M. (1995) J. Biol. Chem. 270, 18774-18780
24. Ostrander, D. B., O'Brien, D. J., Gorman, J. A., and Carman, G. M. (1998) J. Biol. Chem. 273, 18992-19001
25. Dowd, S. R., Bier, M. E., and Patton-Vogt, J. L. (2001) J. Biol. Chem. 276, 3756-3763
26. Boumann, H. A., Damen, M. J., Versluis, C., Heck, A. J., de Kruijff, B., and de Kroon, A. I. (2003) Biochemistry 42, 3054-3059
27. Hosaka, K., Kodaki, T., and Yamashita, S. (1989) J. Biol. Chem. 264, 2053-2059
28. Kim, K.-H., Voelker, D. R., Flocco, M. T., and Carman, G. M. (1998) J. Biol. Chem. 273, 6844-6852
29. Kennedy, E. P. (1986) in Lipids and Membranes: Past, Present, and Future (Op den Kamp, J. A. F., Roelofsen, B., and Wirtz, K. W. A., eds) pp. 171-206, Elsevier Science Publishers B. V., Amsterdam
30. Carman, G. M. (1989) in Phosphatidylcholine Metabolism (Vance, D. E., eds) pp. 165-183, CRC Press, Inc., Boca Raton, FL
31. Wittenberg, J., and Kornberg, A. (1953) J. Biol. Chem. 202, 431-444
32. Peisach, D., Gee, P., Kent, C., and Xu, Z. (2003) Structure (Camb) 11, 703-713
33. Brenner, S. (1987) Nature 329, 21
34. Yuan, C., and Kent, C. (2004) J. Biol. Chem. 279, 17801-17809
35. Yamashita, S., and Hosaka, K. (1997) Biochim. Biophys. Acta 1348, 63-69
36. Ishidate, K. (1997) Biochim. Biophys. Acta 1348, 70-78
37. Nakagami, K., Uchida, T., Ohwada, S., Koibuchi, Y., and Morishita, Y. (1999) Jpn. J. Cancer Res. 90, 1212-1217
38. Hernandez-Alcoceba, R., Fernandez, F., and Lacal, J. C. (1999) Cancer Res. 59, 3112-3118
39. Nakagami, K., Uchida, T., Ohwada, S., Koibuchi, Y., Suda, Y., Sekine, T., and Morishita, Y. (1999) Jpn. J. Cancer Res. 90, 419-424
40. Hernandez-Alcoceba, R., Saniger, L., Campos, J., Nunez, M. C., Khaless, F., Gallo, M. A., Espinosa, A., and Lacal, J. C. (1997) Oncogene 15, 2289-2301
41. Hara, T., Kosaka, N., and Kishi, H. (2002) J. Nucl. Med. 43, 187-199
42. DeGrado, T. R., Baldwin, S. W., Wang, S., Orr, M. D., Liao, R. P., Friedman, H. S., Reiman, R., Price, D. T., and Coleman, R. E. (2001) J. Nucl. Med. 42, 1805-1814
43. Campos, J., Nunez, M. C., Rodriguez, V., Gallo, M. A., and Espinosa, A. (2000) Bioorg. Med. Chem. Lett. 10, 767-770
44. Ramirez, d. M., Rodriguez-Gonzalez, A., Penalva, V., Lucas, L., and Lacal, J. C. (2001) Biochem. Biophys. Res. Commun. 285, 873-879
45. Campos, J. M., Nunez, M. C., Sanchez, R. M., Gomez-Vidal, J. A., Rodriguez-Gonzalez, A., Banez, M., Gallo, M. A., Lacal, J. C., and Espinosa, A. (2002) Bioorg. Med. Chem. 10, 2215-2231
46. Chock, P. B., Rhee, S. G., and Stadtman, E. R. (1980) Annu. Rev. Biochem. 49, 813-843
47. Krebs, E. G., and Beavo, J. A. (1979) Annu. Rev. Biochem. 48, 923-959
48. Kim, K.-H., and Carman, G. M. (1999) J. Biol. Chem. 274, 9531-9538
49. Yu, Y., Sreenivas, A., Ostrander, D. B., and Carman, G. M. (2002) J. Biol. Chem. 277, 34978-34986
50. Nishizuka, Y. (1984) Nature 308, 693-698
51. Nishizuka, Y. (1992) Science 258, 607-614
52. Bell, R, M., and Burns, D. J, (1991) J. Biol. Chem. 266, 4661-4664
53. Levin, D. E., Fields, F. O., Kunisawa, R., Bishop, J. M., and Thorner, J. (1990) Cell 62, 213-224
54. Mellor, H., and Parker, P. J. (1998) Biochem. J. 332, 281-292
55. Levin, D. E., and Bartlett-Heubusch, E. (1992) J. Cell Biol. 116, 1221-1229
56. Rose, M. D., Winston, F., and Heiter, P. (1990) Methods in Yeast Genetics: A Laboratory Course Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
57. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd Ed., Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
58. Ito, H., Yasuki, F., Murata, K., and Kimura, A. (1983) J. Bacteriol. 153, 163-168
59. Schiestl, R. H., and Gietz, R. D. (1989) Curr. Genet. 16, 339-346
60. Innis, M. A., and Gelfand, D. H. (1990) in PCR Protocols: A Guide to Methods and Applications (Innis, M. A., Gelfand, D. H., Sninsky, J. J., and White, T. J., eds) pp. 3-12, Academic Press, Inc., San Diego, CA
61. Kim, K., Kim, K.-H., Storey, M. K., Voelker, D. R., and Carman, G. M. (1999) J. Biol. Chem. 274, 14857-14866
62. Klig, L. S., Homann, M. J., Carman, G. M., and Henry, S. A. (1985) J. Bacteriol. 162, 1135-1141
63. Harlow, E., and Lane, D. (1988) Antibodies: A Laboratory Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
64. Ogita, K., Miyamoto, S., Koide, H., Iwai, T., Oka, M., Ando, K., Kishimoto, A., Ikeda, K., Fukami, Y., and Nishizuka, Y. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 5011-5015
65. Simon, A. J., Milner, Y., Saville, S. P., Dvir, A., Mochly-Rosen, D., and Orr, E. (1991) Proc. Biol. Sci. 243, 165-171
66. Nishizuka, Y. (1988) Nature 334, 661-665
67. Yang, W.-L., and Carman, G. M. (1995) J. Biol. Chem. 270, 14983-14988
68. Yang, W.-L., Bruno, M. E. C., and Carman, G. M. (1996) J. Biol. Chem. 271, 11113-11119
69. Sreenivas, A., Villa-Garcia, M. J., Henry, S. A., and Carman, G. M. (2001) J. Biol. Chem. 276, 29915-29923
70. Laemmli, U. K. (1970) Nature 227, 680-685
71. Yang, W.-L., and Carman, G. M. (1996) J. Biol. Chem. 271, 28777-28783
72. Boyle, W. J., Van der Geer, P., and Hunter, T. (1991) Methods Enzymol. 201, 110-149
73. MacDonald, J. I. S., and Kent, C. (1994) J. Biol. Chem. 269, 10529-10537
74. Porter, T. J., and Kent, C. (1992) Methods Enzymol. 209, 134-146
75. Teegarden, D., Taparowsky, E. J., and Kent, K. (1990) J. Biol. Chem. 265, 6042-6047
76. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
77. Bligh, E. G., and Dyer, W. J. (1959) Can. J. Biochem. Physiol. 37, 911-917
78. Morlock, K. R., Lin, Y.-P., and Carman, G. M. (1988) J. Bacteriol. 170, 3561-3566
79. Perrella, F. (1988) Anal. Biochem. 174, 437-447
80. Segel, I. H. (1970) Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-state Enzyme Systems, John Wiley & Sons, Inc., New York
81. Wang, Y., and Kent, C. (1994) J. Biol. Chem. 270, 17843-17849
82. Iwaki, S., Kihara, A., Sano, T., and Igarashi, Y. (2005) J. Biol. Chem. 280, 6520-6527
83. Roach, P. J. (1991) J. Biol. Chem. 266, 14139-14142
84. Roach, P. J. (1990) FASEB J. 4, 2961-2968
85. Michell, B. J., Chen, Z., Tiganis, T., Stapleton, D., Katsis, F., Power, D. A., Sim, A. T., and Kemp, B. E. (2001) J. Biol. Chem. 276, 17625-17628
86. Choi, M. G., Park, T. S., and Carman, G. M. (2003) J. Biol. Chem. 278, 23610-23616
87. Park, T.-S., Ostrander, D. B., Pappas, A., and Carman, G. M. (1999) Biochemistry 38, 8839-8848
88. Berridge, M. J. (1987) Annu. Rev. Biochem. 56, 159-193
89. Exton, J. H. (1990) J. Biol. Chem. 265, 1-4
90. Downes, C. P., and Macphee, C. H. (1990) Eur. J. Biochem. 193, 1-18
91. Hill, J. E., Myers, A. M., Koerner, T. J., and Tzagoloff, A. (1986) Yeast 2, 163-167