Mitochondrial genotype associated with the occurrence of type 1 diabetes mellitus

Clinical Pediatric Endocrinology

Volumn 9, Issue 1, 2000, Pages 31-35

  Okada, Taisuke ^a,b   Uchigata, Yasuko ^b   Tomoda, Takashi ^a   Iwamoto, Yasuhiko ^b   Tanaka, Masashi ^c   Gong, Jian Sheng ^c  

^a KOCHI MEDICAL SCHOOL   (Japan)

^b TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^c GIFU INTERNATIONAL INSTITUTE OF BIOTECHNOLOGY   (Japan)

Author keywords

Mitochondrial DNA; Oxidative stress; Type 1 diabetes

Indexed keywords

HLA DQ 3 ANTIGEN; HLA DQ 4 ANTIGEN; HLA DQ ANTIGEN; HLA DR 9 ANTIGEN; HLA DR ANTIGEN; HLA DR4 ANTIGEN; MITOCHONDRIAL DNA; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ALU SEQUENCE; ARTICLE; CHILD; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE PHENOTYPE CORRELATION; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

EID: 22544462788     PISSN: 09185739     EISSN: None     Source Type: Journal    
DOI: 10.1297/cpe.9.31     Document Type: Article

References (11)

1. Linnane AW, Maruzuki S, Ozawa T, Tanaka M. Mitochondrial DNA mutations as an important contributor to aging and degenerative diseases. Lancet 1989; i: 642-5.
2. Tanaka M, Gong JS, Zhang J, Yoneda M, et al. Mitochondrial genotype associated with longevity. Lancet 1998; 351: 185-6.
3. Dandona P, Thusu K, Cook S, Snyder B, et al. Oxidative damage to DNA in diabetes mellitus. Lancet 1996; 347: 444-5.
4. Hotta M, Tashiro F, Ikegami H, Niwa H, et al. Pancreatic β cell-specific expression of thioredoxin, an antioxidative and antiapoptotic protein, prevents autoimmune and streptozotocin-induced diabetes. J Exp Med 1998; 188: 1445-51.
5. Takamura T, Kato I, Kimura N, Nakazawa T, et al. Transgenic mice overexpressing type 2 nitric-oxide synthase in pancreatic β cell develop insulin-dependent diabetes without insulitis. J Biol Chem 1998; 273: 2493-6.
6. Cann RL, Stoneking M, Wilson AC. Mitochondrial DNA and human evolution. Nature 1987; 325: 31-6.
7. Tanaka M, Hayakawa M, Ozawa T. Automated sequencing of mitochondrialDNA. Methods Enzymol 1996; 264: 407-21.
8. Kida K, Miura G, Kobayashi T. HLA Immunogenetic heterogeneity in type 1 (insulin-dependent) diabetes among Japanese-HLA antigens and organ-specific autoantibodies. Diabetologia 1989; 32: 34-9.
9. Japan IDDM Epidemiology Study Group. Lack of regional variation in IDDM risk in Japan. Diabetes Care 1993; 16: 796-800.
10. Tajima N, Maruyama M, LaPorte RE. Epidemiology of IDDM. Nippon Rinsho 1997; 55: 527-32.
11. Dominguez C, Gussinye M, Ruiz E, Carrascosa A. Oxidative stress at onset and in early stages of type 1 diabetes in children and adolescents. Diabetes Care 1998; 21: 1736-42.