Effect of intravenous nitroglycerin therapy on erythrocyte antioxidant enzymes

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 20, Issue 3, 2005, Pages 293-296

  Alicigüzel, Yakup ^a   Aktaş, Serpil ^a   Bozan, Hayri ^a   Aslan, Mutay ^a  

^a AKDENIZ UNIVERSITY   (Turkey)

Author keywords

Antioxidant enzymes; Erythrocyte; Glyceryl trinitrate; Reactive oxygen species; ROS

Indexed keywords

ANTIOXIDANT; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; ERYTHROCYTE ENZYME; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE PEROXIDASE; GLYCERYL TRINITRATE; NITRIC OXIDE; ORGANIC NITRATE; REACTIVE OXYGEN METABOLITE; S NITROSOTHIOL; SELENIUM; THIOL GROUP;

ADULT; AGED; ANGINA PECTORIS; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG TOLERANCE; DRUG TRANSFORMATION; ENZYME ACTIVITY; ERYTHROCYTE LEVEL; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; OXIDATIVE STRESS; PRIORITY JOURNAL; SCAVENGING SYSTEM; UNSTABLE ANGINA PECTORIS;

ANTIOXIDANTS; CATALASE; ERYTHROCYTES; FEMALE; GLUTATHIONE PEROXIDASE; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MIDDLE AGED; NITRATES; NITROGLYCERIN; SULFHYDRYL COMPOUNDS;

EID: 22544453618     PISSN: 14756366     EISSN: None     Source Type: Journal    
DOI: 10.1080/14756360500073320     Document Type: Article

References (29)

1. Curfman GD, Heinsimer JA, Lozner EC, Fung HL. Intravenous nitroglycerin in the treatment of spontaneous angina pectoris: A prospective, randomized trial. Circulation 1983;67:276-282.
2. Yusuf S, Wittes J, Friedman L. Overview of results of randomized clinical trials in heart disease. I. Treatments following myocardial infarction. JAMA 1988;260:2088-2093.
3. Sweatman T, Strauss G, Selzer A, Cohn KE. The long-acting hemodynamic effects of isosorbide dinitrate. Am J Cardiol 1972;29:475-480.
4. Ignarro LJ. After 130 years, the molecular mechanism of action of nitroglycerin is revealed. Proc Natl Acad Sci USA 2002;99:7816-7817.
5. Ignarro LJ, Lippton H, Edwards JC, Baricos WH, Hyman AL, Kadowitz PJ, Gruetter CA. Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates. J Pharmacol Exp Ther 1981;218:39-49.
6. Brien JF, McLaughlin BE, Kobus SM, Kawamoto JH, Nakatsu K, Marks GS. Mechanism of glyceryl trinitrate-induced vasodilation. I. Relationship between drug biotransformation, tissue cyclic GMP elevation and relaxation of rabbit aorta. J Pharmacol Exp Ther 1988;244:322-327.
7. Chen Z, Zhang J, Stamler JS. Identification of the enzymatic mechanism of nitroglycerin bioactivation. Proc Natl Acad Sci USA 2002;99:8306-8311.
8. Munzel T, Sayegh H, Freeman BA, Tarpey MM, Harrison DG. Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-tolerance. J Clin Investig 1995;95:187-194.
9. Schulz E, Tsilimingas N, Rinze R, Reiter B, Wendt M, Oelze M. Functional and biochemical analysis of endothelial (dys)function and NO/cGMP signaling in human blood vessels with and without nitroglycerin pretreatment. Circulation 2002;105:1170-1175.
10. Wong PS, Eiserich JP, Reddy S, Lopez CL, Cross CE, van der Vliet A. Inactivation of glutathione S-transferases by nitric oxide-derived oxidants: Exploring a role for tyrosine nitration. Arch Biochem Biophys 2001;394:216-228.
11. Bassenge E, Fink N, Skatchkov M, Fink B. Dietary supplement with vitamin C prevents nitrate tolerance. J Clin Investig 1998;102:67-71.
12. Watanabe H, Kakihana M, Ohtsuka S, Sugishita Y. Randomized, double-blind, placebo-controlled study of supplemental vitamin E on attenuation of the development of nitrate tolerance. Circulation 1997;96:2545-2550.
13. Watanabe H, Kakihana M, Ohtsuka S, Sugishita Y. Randomized, double-blind, placebo-controlled study of ascorbate on the preventive effect of nitrate tolerance in patients with congestive heart failure. Circulation 1998;97:886-891.
14. Beutler E, editor. Red Cell Metabolism: A Manual of Biochemical Methods. 3rd edn. Orlando, FL: Grune & Stratton; 1984.
15. Zinkham WH. An in vitro abnormality of glutathione metabolism in erythrocytes from normal newborns: Mechanism and clinical significance. Pediatrics 1959;23:18-32.
16. Bergmeyer HU, editor. Methods of Enzymatic Analysis, vol. 2 Weinheim, Germany: Verlag Chemie; 1974. p 673-678.
17. Misra HP, Fridovich IJ. The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. Biol Chem 1972;247:3170-3175.
18. Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 1967;70:158-169.
19. Bogaert MG. Clinical pharmacokinetics of glyceryl trinitrate following the use of systemic and topical preparations. Clin Pharmacokinet 1987;12:1-11.
20. Bennett BM, Nakatsu K, Brien JF, Marks GS. Biotransformation of glyceryl trinitrate to glyceryl dinitrate by human hemoglobin. Can J Physiol Pharmacol 1984;62:704-706.
21. Bennett BM, Brien JF, Nakatsu K, Marks GS. Role of hemoglobin in the differential biotransformation of glyceryl trinitrate and isosorbide dinitrate by human erythrocytes. J Pharmacol Exp Ther 1985;234:228-232.
22. Mates JM, Perez-Gomez C, Nunez de Castro I. Antioxidant enzymes and human diseases. Clin Biochem 1999;32:595-603.
23. Cooper CE. Nitric oxide and iron proteins. Biochim Biophys Acta 1999;1411:290-309.
24. Asahi M, Fujii J, Suzuki K, Seo HG, Kuzuya T, Hori MJ. Inactivation of glutathione peroxidase by nitric oxide. Implication for cytotoxicity. Biol Chem 1995;270:21035-21039.
25. Brown GC. Reversible binding and inhibition of catalase by nitric oxide. Eur J Biochem 1995;232:188-191.
26. Radi R. Reactions of nitric oxide with metalloproteins. Chem Res Toxicol 1996;9:828-835.
27. Zimrin D, Reichek N, Bogin KT, Aurigemma G, Douglas P, Berko B. Antianginal effects of intravenous nitroglycerin over 24 hours. Circulation 1988;77:1376-1384.
28. Kurz DJ, Naegeli B, Bertel O. A double-blind, randomized study of the effect of immediate intravenous nitroglycerin on the incidence of postprocedural chest pain and minor myocardial necrosis after elective coronary stenting. Am Heart J 2000;139:35-43.
29. Esposito GA, Dunham G, Granger BB, Tudor GE, Granger CB. Converting i.v. nitroglycerin therapy to nitroglycerin ointment therapy: A comparison of two methods. Am J Crit Care 1998;7:123-130.