Spermatogenic defects in a new inbred strain SD/gShi male rat with small testes

Journal of Reproduction and Development

Volumn 45, Issue 6, 1999, Pages 375-385

  Kaneto, Masako ^a   Kanamori, Susumu ^a   Kishi, Kurajiro ^a  

^a SHIONOGI AND CO LTD   (Japan)

Author keywords

Puberty; SD gShi rat; Small testis; Spermatogenesis

Indexed keywords

EID: 22544453266     PISSN: 09168818     EISSN: 13484400     Source Type: Journal    
DOI: 10.1262/jrd.45.375     Document Type: Article

References (23)

1. Russell LD, Gardner PJ. Testicular ultrastructure and fertility in the restricted color (Hre) rat. Biol Reprod 1974; 11: 631-643.
2. Gill III TJ, Kunz HW. Gene complex controlling growth and fertility linked to the major histocompatibility complex in the rat. Am J Patol 1979; 96: 185-206.
3. Hakamata Y, Kikukawa K, Kamei T, Suzuki K, Taya K, Sasamoto S. A new male hypogonadism mutant rat (hgn/hgn): Concentrations of testosterone (T), luteinizing hormone (LH), and follicle-stimulating hormone (FSH) in the serum and the responsiveness of accessory sex organs to exogenous T, FSH, human chorionic gonadotropin, and luteinizing hormone-releasing hormone. Biol Reprod 1988; 38: 1145-1153.
4. Ikadai H, Ajisawa C, Tsujimura S, Watanabe G, Taya K, Imamichi T. A new male pseudohermaphrodite rat mutant with androgen deficiency. J Reprod Fert 1988; 84: 303-312.
5. Noguchi J, Yoshida M, Ikadai H, Imamichi T, Watanabe G, Taya K. Age-related changes in blood concentrations of FSH, LH and testosterone and testicular morphology in a new sterile mutant with hereditary aspermia. J Reprod Fert 1993; 97: 433-439.
6. Nakao H, Seko S, Sugimori Y, Makino S, Mikazuki K, Inoue T. Establishment of spontaneous hydronephrosis in Sprague-Dawley rats. Exp Anim 1972; 21: 146-147 (in Japanese).
7. Meistrich ML. Evaluation of reproductive toxicity by testicular sperm head counts. J Am Coll Toxicol 1989; 8: 551-567.
8. Clermont Y. Quantitative analysis of spermatogenesis of the rat: a revised model for the renewal of spermatogonia. Am J Anat 1962; 111: 111-129.
9. Sharpe RM. Regulation of spermatogenesis. In: Knobil E, Neill JD (eds.), The Physiology of Reproduction. New York: Raven Press; 1994: 1363-1434.
10. Berndtson WE, Thompson TL. Changing relationships between testis size, Sertoli cell number and spermatogenesis in Sprague-Dawley rats. J Androl 1990; 11: 429-435.
11. Orth JM, Gunsalus GL, Lamperti AA. Evidence from Sertoli cell-depleted rats indicates that spermatid numbers in adults depends on numbers of Sertoli cells produced during perinatal development. Endocrinology 1988; 122: 787-794.
12. Hess RA, Cooke PS, Bunick D, Kirby JD. Adult testicular enlargement induced by neonatal hypothyroidism is accompanied by increased Sertoli and germ cell numbers. Endocrinology 1993; 132: 2607-2613.
13. Meachem SJ, McLachlan RI, Kretser DM, Robertson DM, Wreford NG. Neonatal exposure of rats to recombinant follicle stimulating hormone increases adult Sertoli and spermatogenic cell numbers. Biol Reprod 1996; 54: 36-44.
14. Steinberger A, Steinberger E. Replication pattern of Sertoli cells in maturing rat testis in vivo and in organ culture. Biol Reprod 1971; 4: 84-87.
15. Nagy F. Cell division kinetics and DNA synthesis in immature Sertoli cells of the rat testis. J Reprod Fert 1972; 28: 389-395.
16. Orth JM. Proliferation of Sertoli cells in fetal and postnatal rats: A quantitative autradiographic study. Anat Rec 1982; 203: 485-492.
17. Orth JM. The role of follicle-stimulating hormone in controlling Sertoli cell proliferation in testes of fetal rats. Endocrinology 1984; 115: 1248-1255.
18. Kerr JB, Millar M, Maddocks S, Sharpe RM. Stage-dependent changes in spermatogenesis and Sertoli cells in relation to the onset of spermatogenic failure following withdrawal of testosterone. Anat Rec 1993; 235: 547-559.
19. Henriksén K, Hakovirta H, Parvinen M. Testosterone inhibits and induces apoptosis in rat seminiferous tubules in a stage-specific manner: In situ quantification in squash preparations after administration of ethane dimethane sulfonate. Endocrinology 1995; 136: 3285-3291.
20. Brinkworth MH, Weinbauer GF, Schlatt S, Nieschlag E. Identification of male germ cells undergoing apoptosis in adult rats. J Reprod Fert 1995; 105: 25-33.
21. Vale W, Bilezikjian LM, Rivier C. Reproductive and other roles of inhibins and activins. In: Knobil E, Neill JD (eds.), The Physiology of Reproduction. New York: Raven Press; 1994: 1861-1878.
22. Henriksén K, Kangasniemi M, Parvinen M, Kaipia A, Hakovirta H. In vitro, follicle-stimulating hormone prevents apoptosis and stimulates deoxyribonucleic acid synthesis in the rat seminiferous epithelium in a stage-specific fashion. Endocrinology 1996; 137: 2141-2149.
23. Shetty J, Marathe GK, Dighe RR. Specific immunoneutralization of FSH leads to apoptotic cell death of the pachytene spermatocytes and spermatogonial cells in the rat. Endocrinology 1996; 137:2179-2182.