Thiol-disulphide interchange in tubulin: Kinetics and the effect on polymerization

Biochemical Journal

Volumn 389, Issue 2, 2005, Pages 549-558

  Britto, P J ^a   Knipling, Leslie ^a   McPhie, Peter ^a   Wolff, J ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Leaving group; Mixed disulphide; Polymerization; Stop flow kinetics; Thiol disulphide interchange; Tubulin

Indexed keywords

CHEMICAL BONDS; DIMERS; PH EFFECTS; POLYMERIZATION; REACTION KINETICS; UREA;

DISULPHIDE REAGENTS; NUCLEOTIDES; THIOL-DISULPHIDE INTERCHANGE; TUBULIN;

PROTEINS;

2,2' DITHIODIPYRIDINE; 5,5' DITHIOBIS(2 NITROBENZOIC ACID); CYSTEINE; MESYLIC ACID METHYL ESTER; METHYL METHANETHIOSULPHONATE; N OCTYL DITHIO 2 NITROBENZOATE; NITROBENZOIC ACID DERIVATIVE; TRYPTOPHAN; TUBULIN; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION KINETICS; CIRCULAR DICHROISM; DISULFIDE BOND; IONIC STRENGTH; KINETICS; MICROTUBULE; MICROTUBULE ASSEMBLY; PH; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN STRUCTURE;

2,2'-DIPYRIDYL; ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; BIOPOLYMERS; CYSTEINE; DISULFIDES; DITHIONITROBENZOIC ACID; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; KINETICS; METHYL METHANESULFONATE; MOLECULAR STRUCTURE; NITROBENZOATES; PROTEIN DENATURATION; SULFHYDRYL COMPOUNDS; TUBULIN;

EID: 22544440279     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20042118     Document Type: Article

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