The effects of the GABAA antagonist bicuculline on cocaine self-administration in rats exposed to lead during gestation/lactation

Pharmacology Biochemistry and Behavior

Volumn 80, Issue 4, 2005, Pages 611-619

  Valles, Rodrigo ^a   Rocha, Angelica ^a   Cardon, Aaron ^a   Bratton, Gerald R ^b   Nation, Jack R ^a,b  

^a TEXAS A AND M UNIVERSITY   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Cocaine; GABA; Lead; Stress

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; BICUCULLINE; COCAINE; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; LEAD;

ANIMAL BEHAVIOR; ARTICLE; BODY WEIGHT; COCAINE DEPENDENCE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG SELF ADMINISTRATION; FEMALE; FOOD INTAKE; INSTRUMENTAL CONDITIONING; NONHUMAN; PREGNANCY; PRENATAL EXPOSURE; PRIORITY JOURNAL; RAT; STRESS; ANIMAL; DOSE RESPONSE; DRUG ANTAGONISM; EATING; NEWBORN; PHYSIOLOGY; PSYCHOLOGICAL ASPECT; REWARD; SPRAGUE DAWLEY RAT;

ANIMALIA;

ANIMALS; ANIMALS, NEWBORN; BICUCULLINE; BODY WEIGHT; COCAINE-RELATED DISORDERS; CONDITIONING, OPERANT; DOSE-RESPONSE RELATIONSHIP, DRUG; EATING; FEMALE; GABA ANTAGONISTS; LEAD; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; REWARD; SELF ADMINISTRATION;

EID: 22444433546     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2005.01.011     Document Type: Article

References (30)

1. Brebner K, Froestl W, Andrews M, Phelan R, Roberts DCS. The GABA-B agonist CGP 44532 decreases cocaine self-administration in rats: demonstration using a progressive ratio and a discrete trials procedure. Neuropharmacology 1999;38:1797-804.
2. Canfield RL, Henderson Jr CR, Cory-Slechta DA, Cox C, Jusko TA, Lanphear BP. Intellectual impairments in children with blood lead concentrations below 10 μg per deciliter. N Engl J Med 2003;348: 1517-26.
3. Covington HE, Miczek KA. Repeated social-defeat stress, cocaine or morphine effects on behavioral sensitization and intravenous cocaine self-administration "binges". Psychopharmacology 2001;158:388-98.
4. David V, Gold LH, Koob GF, Cazala P. Anxiogenic-like effects limit rewarding effects of cocaine in BALB/cByJ mice. Neuropsychopharmacology 2001;24:300-18.
5. Dearth RK, Hiney JK, Srivasta VK, Burdick SB, Bratton GR, Dees WL. Effects of lead (Pb) exposure during gestation and lactation on female pubertal development in the rat. Reprod Toxicol 2003;16:343-52.
6. Ensminger ME, Anthony JC, McCord J. The inner city and drug use: initial findings from an epidemiological study. Drug Alcohol Depend 1997;48: 75-184.
7. Goeders NE. The HPA axis and cocaine reinforcement. Psychoneuroendocrinology 2002;27:13-33.
8. Gonzalez LE, Ouagazzal A, File SE. Stimulation of benzodiazepine receptors in the dorsal hippocampus and medina raphe reveals differential GABAergic control in two animal tests of anxiety. Eur J Neurosci 1998;10:3673-80.
9. A receptor in male rats in association with anxiety and altered pharmacology - a comparison with female rats. Neuropharmacology 2002;43:701-14.
10. Harwell TS, Spence MR, Sands A, Iguchi MY. Substance use in an inner-city family planning population. J Reprod Med 1996;41:704-10.
11. Holson RR, Pearce B. Principles and pitfalls in the analysis of prenatal treatment effects in multiparious species. Neurotoxicol Teratol 1992;14:221-8.
12. Lasley SM, Gilbert ME. Rat hippocampal glutamate and GABA release exhibit biphasic effects as a function of chronic lead exposure level. Toxicol Sci 2002;66:139-47.
13. Lasley SM, Green MC, Gilbert ME. Influence of exposure period on in vivo hippocampal glutamate and GABA release in rats chronically exposed to lead. Neurotoxicology 1999;120:619-29.
14. Leret ML, Garcia-Uceda F, Antonio MT. Effects of maternal lead administration on monamergic, GABAergic and glutamatergic systems. Brain Res Bull 2002;58:469-73.
15. Lynch WJ, Carroll ME. Regulation of drug intake. Exp Clin Psychopharmacol 2001;9:131-43.
16. Moreira EG, Vassilief I, Vassilief VS. Developmental lead exposure: behavioral alterations in the short and long term. Neurotoxicol Teratol 2001;23:489-95.
17. Nation JR, Heard HM, Cardon AL, Valles R, Bratton GR. Perinatal lead exposure and relapse to drug-seeking behavior in the rat: a cocaine reinstatement study. Psychopharmacology 2003;168:236-43.
18. Nation JR, Miller DK, Bratton GR. Perinatal lead exposure alters the stimulatory properties of cocaine at PND 30 and PND 90 in the rat. Neuropsychopharmacology 2000;23:444-54.
19. Nation JR, Smith KR, Bratton GR. Early developmental lead exposure increases sensitivity to cocaine in a self-administration paradigm. Pharmacol Biochem Behav 2004;77:127-35.
20. National Institute of Public Health (NIH) publication no. 85-23 (Revised 1996) Guide for the care and use of laboratory animals (Guide) Bethseda, MD.
21. Nutt DJ, Malizia AL. New insights into the role of the GABA(A)-benzodiazepine receptor in psychiatric disorder. Br J Psychiatr 2001;179:390-6.
22. Pirkle JL, Kaufmann RB, Brody DJ, Hickman T, Gunter EW, Paschal DC. Exposure of the US population to lead, 1991-1994. Environ Health Perspect 1998;106:745-50.
23. Pokora MJ, Richfield EK, Cory-Slechta DA. Preferential vulnerability of nucleus accumbens dopamine binding sites to low-level lead exposure: time course of effects and interactions with chronic dopamine agonist treatments. J Neurochem 1996;67:1540-50.
24. Rocha A, Valles R, Cardon AL, Bratton GR, Nation JR. Self-administration of heroin in rats: effects of low-level lead exposure during gestation and lactation. Neuropsychopharmacology 2004;174:203-10.
25. A receptor gene regulation in the brain and anxiety behavior. Steroids 2002;67:519-28.
26. Thielen SK, Shekhar A. Amygdala priming results in conditioned place avoidance. Pharmacol Biochem Behav 2002;71:401-6.
27. Valles R, Cardon AL, Heard HM, Bratton GR, Nation JR. Morphine conditioned place preference is attenuated by perinatal lead exposure. Pharmacol Biochem Behav 2003;75:295-300.
28. Van de Kar LD, Blair ML. Forebrain pathways mediating stress-induced hormone secretion frontiers. Neuroendocrinology 1999;20:1-48.
29. Yagi K, Onaka T. Chlordiazepoxide discriminates between the neural circuits mediating neuroendocrine responses to fear- and anxiety-producing stimuli in the rat. Neurosci Res 1996;22:151-8.
30. B receptor stimulation induces antianxiety profile in rats. Pharmacol Biochem Behav 2001;69:9-15.