Isolation and comparative expression analysis of the Myc-regulatory proteins Mad1, Mad3, and Mnt during Xenopus development

Developmental Dynamics

Volumn 233, Issue 4, 2005, Pages 1554-1559

  Juergens, Kathrin ^a   Rust, Barbara ^a   Pieler, Tomas ^a   Henningfeld, Kristine A ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Mad; Myc; Neural crest; Neural tube; Notochord; Xenopus laevis

Indexed keywords

BUB1 RELATED PROTEIN; MAX PROTEIN; MYC PROTEIN; PROTEIN MAD1; PROTEIN MNT; REGULATOR PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DIMERIZATION; EMBRYO DEVELOPMENT; NEURAL CREST; NONHUMAN; NOTOCHORD; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN ISOLATION; PROTEIN LOCALIZATION; REPRESSOR GENE; TRANSCRIPTION REGULATION; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; CELL CYCLE PROTEINS; EMBRYO, NONMAMMALIAN; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE LIBRARY; MOLECULAR SEQUENCE DATA; ORGAN SPECIFICITY; PROTO-ONCOGENE PROTEINS C-MYC; REPRESSOR PROTEINS; SEQUENCE ALIGNMENT; XENOPUS LAEVIS; XENOPUS PROTEINS;

XENOPUS LAEVIS;

EID: 22244464505     PISSN: 10588388     EISSN: None     Source Type: Journal    
DOI: 10.1002/dvdy.20470     Document Type: Article

References (36)

1. Ayer DE, Eisenman RN. 1993. A switch from Myc:Max to Mad:Max heterocomplexes accompanies monocyte/macrophage differentiation. Genes Dev 7:2110-2119.
2. Ayer DE, Laherty CD, Lawrence QA, Armstrong AP, Eisenman RN. 1996. Mad proteins contain a dominant transcription repression domain. Mol Cell Biol 16: 5772-5781.
3. Baudino TA, Cleveland JL. 2001. The Max network gone mad. Mol Cell Biol 21:691-702.
4. Bejarano MT, Albihn A, Cornvik T, Brijker SO, Asker C, Osorio LM, Henriksson M. 2000. Inhibition of cell growth and apoptosis by inducible expression of the transcriptional repressor Mad1. Exp Cell Res 260:61-72.
5. Bellmeyer A, Krase J, Lindgren J, LaBonne C. 2003. The protooncogene c-myc is an essential regulator of neural crest formation in Xenopus. Dev Cell 4:827-839.
6. Bouchard C, Dittrich O, Kiermaier A, Dohmann K, Menkel A, Eilers M, Luscher B. 2001. Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter. Genes Dev 15:2042-2047.
7. Gehring S, Rottmann S, Menkel AR, Mertsching J, Krippner-Heidenreich A, Luscher B. 2000. Inhibition of proliferation and apoptosis by the transcriptional represser Mad1. Repression of Fas-induced caspase-8 activation. J Biol Chem 275:10413-10420.
8. Grandori C, Cowley SM, James LP, Eisenman RN 2000. The Myc/Max/Mad network and the transcriptional control of cell behavior. Ann Rev Cell Dev Biol 16: 653-699.
9. Harland RM. 1991. In situ hybridization: an improved whole-mount method for Xenopus embryos. Methods Cell Biol 36: 685-695.
10. Hurlin PJ, Ayer DE, Grandori C, Eisenman RN. 1994. The Max transcription factor network: involvement of Mad in differentiation and an approach to identification of target genes. Cold Spring Harb Symp Quant Biol 59:109-116.
11. Hurlin PJ, Queva C, Koskinen PJ, Steingrimsson E, Ayer DE, Copeland NG, Jenkins NA, Eisenman RN. 1995. Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation. Embo J 14:5646-5659.
12. Hurlin PJ, Queva C, Eisenman RN. 1997. Mnt, a novel Max-interacting protein is coexpressed with Myc in proliferating cells and mediates repression at Myc binding sites. Genes Dev 11:44-58.
13. Hurlin PJ, Zhou Z-Q, Toyo-oka, K, Ota S, Walker, WL, Hirotsune, S, Wynshaw-Boris A. 2003. Deletion of Mnt leads to disrupted cell cycle control and tumorigenesis. Embo J 22:4584-4596.
14. Joseph EM, Melton DA. 1997. Xnr4: a Xenopus nodal-related gene expressed in the Spemann organizer. Dev Biol 184: 367-372.
15. King MW, Roberts JM, Eisenman RN. 1986. Expression of the c-myc proto-oncogene during development of Xenopus laevis. Mol Cell Biol 6:4499-4508.
16. King MW, Blackwood EM, Eisenman RN. 1993. Expression of two distinct homologues of Xenopus Max during early development. Cell Growth Differ 4:85-92.
17. Laherty CD, Yang WM, Sun JM, Davie JR, Seto E, Eisenman RN. 1997. Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression. Cell 89:349-356.
18. Lüscher B. 2001. Function and regulation of the transcription factors of the Myc/ Max/Mad network. Gene 277:1-14.
19. Lüscher B, Larsson LG. 1999. The basic region/helix-loop-helix/ leucine zipper domain of Myc proto-oncoproteins: function and regulation. Oncogene 18:2955-2966.
20. Meroni G, Reymond A, Alcalay M, Borsani G, Tanigami A, Tonlorenzi R, Nigro CL, Messali S, Zollo M, Ledbetter DH, Brent R, Ballabio A, Carrozzo R. 1997. Rox, a novel bHLHZip protein expressed in quiescent cells that heterodimerizes with Max, binds a non-canonical E box and acts as a transcriptional repressor. Embo J 16:2892-2906.
21. Newman CS, Krieg PA. 1999. Alternative splicing and embryonic expression of the Xenopus mad4 bHLH gene. Dev Dyn 215: 170-178.
22. Nieuwkoop PD, Faber J. 1967. Normal table of Xenopus laevis (Daudin). Amsterdam: North-Holland.
23. O'Hagan RC, Schreiber-Agus N, Chen K, David G, Engelman JA, Schwab R, Alland L, Thomson C, Running DR, Sacchettini JC, Meltzer P, DePinho RA. 2000. Gene-target recognition among members of the myc superfamily and implications for oncogenesis. Nat Genet 24: 113-119.
24. Pulverer B, Sommer A, McArthur GA, Eisenman RN, Luscher B. 2000. Analysis of Myc/Max/Mad network members in adipogenesis: inhibition of the proliferative burst and differentiation by ectopically expressed Mad1. J Cell Physiol 183: 399-410.
25. Queva C, Hurlin PJ, Foley KP, Eisenman RN. 1998. Sequential expression of the MAD family of transcriptional repressors during differentiation and development. Oncogene 16:967-977.
26. Roussel MF, Ashmun RA, Sherr CJ, Eisenman RN, Ayer DE. 1996. Inhibition of cell proliferation by the Mad1 transcriptional repressor. Mol Cell Biol 16:2796-2801.
27. Roy B, Reisman D. 1995. Inducible expression of Mad accelerates growth arrest of serum deprived human glioblastoma cells. Cell Biol Int 19:307-313.
28. Sadaghiani B, Thiebaud CH. 1987. Neural crest development in the Xenopus laevis embryo, studied by interspecific transplantation and scanning electron microscopy. Dev Biol 124:91-110.
29. Saka Y, Smith JC. 2001. Spatial and temporal patterns of cell division during early Xenopus embryogenesis. Dev Biol 229:307-318.
30. Schreiber-Agus N, Torres R, Horner J, Lau A, Jamrich M, DePinho RA. 1993. Comparative analysis of the expression and oncogenic activities of Xenopus c-, N-, and L-myc homologs. Mol Cell Biol 13: 2456-2468.
31. Sommer A, Hilfenhaus S, Menkel A, Kremmer E, Seiser C, Loidl P, Luscher B. 1997. Cell growth inhibition by the Mad/ Max complex through recruitment of histone deacetylase activity. Curr Biol 7: 357-365.
32. Toyo-oka K, Hirotsune S, Gambello MJ, Zhou ZQ, Olson L, Rosenfeld MG, Eisenman R, Hurlin P, Wynshaw-Boris A. 2004. Loss of the Max-interacting protein Mnt in mice results in decreased viability, defective embryonic growth and craniofacial defects: relevance to Miller-Dieker syndrome. Hum Mol Genet 13:1057-1067.
33. Vize PD, Vaughan A, Krieg P. 1990. Expression of the N-myc proto-oncogene during the early development of Xenopus laevis. Development 110:885-896.
34. Werner S, Beer HD, Mauch C, Luscher B. 2001. The Mad1 transcription factor is a novel target of activin and TGF-beta action in keratinocytes: possible role of Mad1 in wound repair and psoriasis. Oncogene 20:7494-7504.
35. Xu D, Popov N, Hou M, Wang Q, Bjorkholm M, Gruber A, Menkel AR, Henriksson M. 2001. Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells. Proc Natl Acad Sci USA 98:3826-3831.
36. Zhou ZQ, Hurlin PJ. 2001. The interplay between Mad and Myc in proliferation and differentiation. Trends Cell Biol 11:S10-14.