Adenovirus-mediated expression of heparin cofactor II inhibits thrombin-induced cellular responses in fibroblasts and vascular smooth muscle cells

Thrombosis Research

Volumn 116, Issue 4, 2005, Pages 357-363

  Hayakawa, Yumiko ^a   Hirashima, Yutaka ^a   Yamamoto, Hiromichi ^a   Hayashi, Nakamasa ^a   Kurimoto, Masanori ^a   Kuwayama, Naoya ^a   Endo, Shunro ^a  

^a TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Adenovirus; Fibroblasts; Heparin cofactor II; Interleukin 6; Tissue type plasminogen activator; Vascular smooth muscle cells

Indexed keywords

ADENOVIRUS VECTOR; HEPARIN COFACTOR II; INTERLEUKIN 6; THROMBIN; TISSUE PLASMINOGEN ACTIVATOR;

ARTICLE; CELL CULTURE; CELL FUNCTION; CONTROLLED STUDY; CYTOKINE RELEASE; FIBROBLAST; GENE TRANSFER; HUMAN; HUMAN CELL; PHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ADENOVIRIDAE; CELLS, CULTURED; FIBROBLASTS; HEPARIN COFACTOR II; HUMANS; INTERLEUKIN-6; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; THROMBIN; TISSUE PLASMINOGEN ACTIVATOR; TRANSDUCTION, GENETIC;

EID: 22244457948     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2005.01.003     Document Type: Article

References (36)

1. M.A. Shuman Thrombin-cellular interactions Ann. N. Y. Acad. Sci. 485 1986 228 239
2. R. Kranzhofer, S.K. Clinton, K. Ishii, S.R Coughlin, J.W. Fenton II, and P. Libby Thrombin potently stimulates cytokine production in human vascular smooth muscle cells but not in mononuclear phagocytes Circ. Res. 79 1996 286 294
3. V.J. LaMorte, E.D. Kennedy, L.R. Collins, D. Goldstein, A.T. Harootunian, and J.H. Brown A requirement for Ras protein function in thrombin-stimulated mitogenesis in astrocytoma cells J. Biol. Chem. 268 1993 19411 19415
4. C.A. McNamara, I.J. Sarembock, L.W. Gimple, J.W. Fenton II, S.R. Coughlin, and G.K. Owens Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor J. Clin. Invest. 91 1993 94 98
5. A. Ludwicka-Bradley, E. Tourkina, S. Suzuki, E. Tyson, M. Bonner, and J.W. Fenton II Thrombin upregulates interleukin-8 in lung fibroblasts via cleavage of proteolytically activated receptor-I and protein kinase C-γ activation Am. J. Respir. Cell Mol. Biol. 22 2000 235 243
6. D.H. Carney, J. Stirenberg, and J.W. Fenton II Initiation of proliferative events by human α-thrombin requires both receptor binding and enzyme activity J. Cell. Biochem. 26 1984 181 195
7. T. Tokunou, T. Ichiki, K. Takeda, Y. Funakoshi, N. Iino, and A. Takeshita cAMP response element-binding protein mediates thrombin-induced proliferation of vascular smooth muscle cells Arterioscler. Thromb. Vasc. Biol. 21 2001 1764 1769
8. L.M. Biasucci, A. Vitelli, G. Liuzzo, S. Altamura, G. Caligiuri, and C. Monaco Elevated levels of interleukin-6 in unstable angina Circulation 94 1996 874 877
9. G. Liuzzo, A. Buffon, L.M. Biasucci, J.R. Gallimore, G. Caligiuri, and A. Vitelli Enhanced inflammatory response to coronary angioplasty in patients with severe unstable angina Circulation 98 1998 2370 2376
10. Y. Hojo, U. Ikeda, T. Katsuki, O. Mizuno, H. Fukazawa, and K. Kurosaki Interleukin-6 expression in coronary circulation after coronary angioplasty as a risk factor for restenosis Heart 84 2000 83 87
11. L.E. Sower, C.J. Froelich, D.H. Carney, J.W. Fenton II, and G.R. Klimpel Thrombin induces IL-6 production in fibroblasts and epithelial cells: evidence for the involvement of the seven-transmembrane domain (STD) receptor for α-thrombin J. Immunol. 155 1995 895 901
12. T. Tokunou, T. Ichiki, K. Takeda, Y. Funakoshi, N. Iino, and H. Shimokawa Thrombin induces interleukin-6 expression through the cAMP response element in vascular smooth muscle cells Arterioscler. Thromb. Vasc. Biol. 21 2001 1759 1763
13. Y. Hayakawa, S. Tazawa, T.-.I. Ishikawa, K. Niiya, and N. Sakuragawa Thrombin regulation of tissue-type plasminogen activator synthesis in cultured human fetal lung fibroblasts Thromb. Res. 71 1993 457 465
14. Y. Hayakawa, S. Tazawa, T.-.I. Ishikawa, K. Niiya, and N. Sakuragawa Transcriptional regulation of tissue- and urokinase-type plasminogen activator genes by thrombin in human fetal lung fibroblasts Thromb. Haemost. 74 1995 704 710
15. D.M. Tollefsen Antithrombin deficiency C.R. Scriver A.L. Beaudet W.S. Sly D. Valle The metabolic and molecular bases of inherited disease 8th ed. 2001 McGraw-Hill New York 4455 4471
16. D.M. Tollefsen, C.A. Pestka, and W.J. Monafo Activation of heparin cofactor II by dermatan sulfate J. Biol. Chem. 258 1983 6713 6716
17. E.A. McGuire, and D.M. Tollefsen Activation of heparin cofactor II by fibroblasts and vascular smooth muscle cells J. Biol. Chem. 262 1987 169 175
18. H. Niwa, K. Yamamura, and J. Miyazaki Efficient selection for high-expression transfectants with a novel eukaryotic vector Gene 108 1991 193 200
19. S. Miyake, M. Makimura, Y. Kanegae, S. Harada, Y. Sato, and K. Takamori Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome Proc. Natl. Acad. Sci. U. S. A. 93 1996 1320 1324
20. Y. Hayakawa, T. Hayashi, T. Hayashi, K. Niiya, and N. Sakuragawa Selective activation of heparin cofactor II by a sulfated polysaccharide isolated from the leaves of Artemisia princeps Blood Coagul. Fibrinolysis 6 1995 643 649
21. Y. Hayakawa, Y. Hirashima, M. Kurimoto, N. Hayashi, H. Hamada, and N. Kuwayama Contribution of basic residues of the A helix of heparin cofactor II to heparin- or dermatan sulfate-mediated thrombin inhibition FEBS Lett. 522 2002 147 150
22. V. Bhakta, M.E. Begbie, A. Gupta, V. Sandhu, and W.P. Sheffield Heparin cofactor II is more sensitive than antithrombin to secretory impairment arising from mutations introduced into its carboxy-terminal region Thromb. Res. 113 2004 163 173
23. M.M. Maimone, and D.M. Tollefsen Structure of a dermatan sulfate hexasaccharide that binds to heparin cofactor II with high affinity J. Biol. Chem. 265 1990 18263 18271
24. L.C. Rosenberg, H.U. Choi, L.H. Tang, T.L. Johnson, S. Pal, and C. Webber Isolation of dermatan sulfate proteoglycans from mature bovine articular cartilages J. Biol. Chem. 260 1985 6304 6313
25. H.U. Choi, T.L. Johnson, S. Pal, L.H. Tang, L.C. Rosenberg, and PJ. Neame Characterization of the dermatan sulfate proteoglycans, DS-PGI and DS-PGII, from bovine articular cartilage and skin isolated by octyl-sepharose chromatography J. Biol. Chem. 264 1989 2876 2884
26. R.A. Shirk, F.C. Church, and W.D. Wagner Arterial smooth muscle cell heparan sulfate proteoglycans accelerate thrombin inhibition by heparin cofactor II Arterioscler. Thromb. Vasc. Biol. 16 1996 1138 1146
27. F.C. Church, and M.R. Hoffman Heparin cofactor II and thrombin: heparin-binding proteins linking hemostasis and inflammation Trends Cardiovasc. Med. 4 1994 140 146
28. D.M. Tollefsen Insight into the mechanism of action of heparin cofactor II Thromb. Haemost. 74 1995 1209 1214
29. H. Ragg, and G. Preibisch Structure and expression of the gene coding for the human serpin hLS2 J. Biol. Chem. 263 1988 12129 12134
30. P.-.B. Kamp, A. Strathmann, and H. Ragg Heparin cofactor II, antithrombin-β and their complexes with thrombin in human tissues Thromb. Res. 101 2001 483 491
31. T. Hayashi, T. Kaji, Y. Hayakawa, K. Niiya, M. Sakamoto, and N. Sakuragawa Inhibitory effect of heparin cofactor II on thrombin-stimulated prostacyclin production by cultured vascular smooth muscle cells Thromb. Res. 64 1991 321 330
32. R.A. Shirk, N. Parthasarathy, J.D. San Antonio, F.C. Church, and W.D. Wagner Altered dermatan sulfate structure and reduced heparin cofactor II-stimulating activity of biglycan and decorin from human atherosclerotic plaque J. Biol. Chem. 275 2000 18085 18092
33. K. Yamanaga, T. Yuuki, M. Tsukada, H. Koshiba, T. Nakajima, and K. Takechi Heparin cofactor II inhibits thrombus formation in a rat thrombosis model Thromb. Res. 98 2000 95 101
34. L. He, C.P. Vicente, R.J. Westrick, D.T. Eitzman, and D.M. Tollefsen Heparin cofactor II inhibits arterial thrombosis after endothelial injury J. Clin. Invest. 109 2002 213 219
35. N. Takamori, H. Azuma, M. Kato, S. Hashizume, K.-.I. Aihara, and M. Akaike High plasma heparin cofactor II activity is associated with reduced incidence of in-stent restenosis after percutaneous coronary intervention Circulation 109 2004 481 486
36. K.-.I. Aihara, H. Azuma, N. Takamori, Y. Kanagawa, M. Akaike, and M. Fujimura Heparin cofactor II is a novel protective factor against carotid atherosclerosis in elderly individuals Circulation 109 2004 2761 2765