Cloning and functional characterization of the rat α2B-adrenergic receptor gene promoter region: Evidence for binding sites for erythropoiesis-related transcription factors GATA1 and NF-E2

Biochemical Pharmacology

Volumn 70, Issue 4, 2005, Pages 606-617

  Schaak, Stéphane ^a   Cussac, Daniel ^a   Labialle, Stéphane ^a   Mignotte, Vincent ^a   Paris, Hervé ^a  

^a INSERM   (France)

Author keywords

2b adrenergic receptor; GATA1; NF E2; Promoter; RNG; Transcription factors

Indexed keywords

ALPHA 2B ADRENERGIC RECEPTOR; DEOXYRIBONUCLEASE I; LUCIFERASE; RIBONUCLEASE; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR NF E2; TRANSCRIPTION FACTOR SP1;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BAY REGION BINDING SITE; BINDING AFFINITY; BLOOD; BRAIN; CHROMATIN; CONTROLLED STUDY; DNA FLANKING REGION; ENZYME ASSAY; ERYTHROPOIESIS; FEMALE; GEL MOBILITY SHIFT ASSAY; GENE FUNCTION; GENE ISOLATION; GENETIC CODE; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; KIDNEY; KIDNEY PROXIMAL TUBULE; LIVER; MOLECULAR CLONING; MOLECULAR GENETICS; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PLACENTA; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAT; REPORTER GENE; RNA PROBE; START CODON; TATA BOX; TISSUE DISTRIBUTION; TRANSCRIPTION INITIATION SITE;

ANIMALS; BASE SEQUENCE; BINDING SITES; CLONING, MOLECULAR; DNA; DNA PRIMERS; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ERYTHROID-SPECIFIC DNA-BINDING FACTORS; GATA1 TRANSCRIPTION FACTOR; MOLECULAR SEQUENCE DATA; NF-E2 TRANSCRIPTION FACTOR; PROMOTER REGIONS (GENETICS); RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, BETA-2; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 22144498489     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.05.024     Document Type: Article

References (49)

1. D.B. Bylund, D.C. Eikenberg, J.P. Hieble, S.Z. Langer, R.J. Lefkowitz, and K.P. Minneman International Union of Pharmacology nomenclature of adrenoceptors Pharmacol Rev 46 1994 121 136
2. L. Hein Transgenic models of α2-adrenergic receptor subtype function Rev Physiol Biochem Pharmacol 142 2001 161 185
3. R.E. Link, K. Desai, L. Hein, M.E. Stevens, A. Chruscinski, and D. Bernstein Cardiovascular regulation in mice lacking α2-adrenergic receptor subtypes b and c Science 273 1996 803 805
4. K.P. Makaritsis, D.E. Handy, C. Johns, B. Kobilka, I. Gavras, and H. Gavras Role of the α2B-adrenergic receptor in the development of salt-induced hypertension Hypertension 33 1999 14 17
5. W. Lorenz, J.W. Lomasney, S. Collins, J.W. Regan, M.G. Caron, and R.J. Lefkowitz Expression of three α2-adrenergic receptor subtypes in rat tissues: implications for α2 receptor classification Mol Pharmacol 38 1990 599 603
6. D.E. Handy, C.S. Flordellis, N.N. Bogdanova, M.R. Bresnahan, and H. Gavras Diverse tissue expression of rat α2-adrenergic receptor genes Hypertension 21 1993 861 865
7. A. Tavares, D.E. Handy, N.N. Bogdanova, D.L. Rosene, and H. Gavras Localization of α2A- and α2B-adrenergic receptor subtypes in brain Hypertension 27 1996 449 455
8. U.H. Winzer-Serhan, and F.M. Leslie α2B-adrenoceptor mRNA expression during rat brain development Brain Res Dev Brain Res 100 1997 90 100
9. D. Cussac, S. Schaak, C. Denis, C. Flordellis, D. Calise, and H. Paris High level of α2-adrenoceptor in rat foetal liver and placenta is due to α2B-subtype expression in haematopoietic cells of the erythrocyte lineage Br J Pharmacol 133 2001 1387 1395
10. M. Philipp, M.E. Brede, K. Hadamek, M. Gessler, M.J. Lohse, and L. Hein Placental α2-adrenoceptors control vascular development at the interface between mother and embryo Nat Genet 31 2002 311 315
11. R. Dawson Jr., and S. Oparil Renal catecholamines and α2-adrenergic receptors in salt-related and genetic hypertension Pharmacology 34 1987 131 142
12. A. El Attari, W. Qing, D. Ben-Ishay, A. Parini, and J.P. Dausse α-adrenoceptor properties in rat strains sensitive or resistant to salt-induced hypertension Fundam Clin Pharmacol 3 1989 483 495
13. C.K. Stanko, and D.D. Smyth Proximal tubular α2-adrenoceptor density in the spontaneously hypertensive rat Am J Hypertens 4 1991 64 67
14. J.C. Muir, L. Huang, J.K. Harrison, D.L. Rosin, and M.D. Okusa Regulation of rat renal α2B-adrenergic receptors by potassium depletion Am J Physiol 266 1994 F316 F324
15. L. Huang, Y.Y. Wei, A. Momose-Hotokezaka, J. Dickey, and M.D. Okusa α2B-adrenergic receptors: immunolocalization and regulation by potassium depletion in rat kidney Am J Physiol 270 1996 F1015 F1026
16. E.P. Nord, M.J. Howard, A. Hafezi, P. Moradeshagi, S. Vaystub, and P.A. Insel α2-adrenergic agonists stimulate Na+ to H+ antiport activity in the rabbit renal proximal tubule J Clin Invest 80 1987 1755 1762
17. L. Diop, A. Parini, J.P. Dausse, and D. Ben-Ishay Dietary sodium regulation of α2-adrenoceptors in Sabra hypertensive (SHB) and normotensive (SBN) rats J Hypertens 2 1984 S163 S165
18. D.E. Handy, M.T. Zanella, A. Kanemaru, A. Tavares, C. Flordellis, and H. Gavras A negative regulatory element in the promoter region of the rat α2A-adrenergic receptor gene overlaps an SP1 consensus binding site Biochem J 311 1995 541 547
19. J.S. Saulnier-Blache, Q. Yang, J.D. Sherlock, and S.M. Lanier Analysis of the α2C-adrenergic receptor gene promoter and its cell-type-specific activity Mol Pharmacol 50 1996 1432 1442
20. D. Cussac, S. Schaak, C. Gales, C. Flordellis, C. Denis, and H. Paris α2b-adrenergic receptors activate MAPK and modulate proliferation of primary cultured proximal tubule cells Am J Physiol Renal Physiol 282 2002 F943 F952
21. P. Chomczynski, and N. Sacchi Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction Anal Biochem 162 1987 156 159
22. S. Schaak, J.C. Devedjian, C. Cayla, Y. Sender, and H. Paris Molecular cloning, sequencing and functional study of the promoter region of the human α2C4-adrenergic receptor gene Biochem J 328 1997 431 438
23. J.D. Dignam, R.M. Lebovitz, and R.G. Roeder Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei Nucl Acids Res 11 1983 1475 1489
24. E. deBoer, M. Antoniou, V. Mignotte, L. Wall, and F. Grosveld The human beta-globin promoter; nuclear protein factors and erythroid specific induction of transcription Embo J 7 1988 4203 4212
25. R. Javahery, A. Khachi, K. Lo, B. Zenzie-Gregory, and S.T. Smale DNA sequence requirements for transcriptional initiator activity in mammalian cells Mol Cell Biol 14 1994 116 127
26. M. Kozak An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs Nucl Acids Res 15 1987 8125 8148
27. D.W. Zeng, J.K. Harrison, D.D. D'Angelo, C.M. Barber, A.L. Tucker, and Z.H. Lu Molecular characterization of a rat α2B-adrenergic receptor Proc Natl Acad Sci USA 87 1990 3102 3106
28. V. Mignotte, L. Wall, E. deBoer, F. Grosveld, and P.H. Romeo Two tissue-specific factors bind the erythroid promoter of the human porphobilinogen deaminase gene Nucl Acids Res 17 1989 37 54
29. C. Cayla, P. Heinonen, L. Viikari, S. Schaak, A. Snapir, and A. Bouloumie Cloning, characterisation and identification of several polymorphisms in the promoter region of the human α2B-adrenergic receptor gene Biochem Pharmacol 67 2004 469 478
30. D.E. Berkowitz, D.T. Price, E.A. Bello, S.O. Page, and D.A. Schwinn Localization of messenger RNA for three distinct α2-adrenergic receptor subtypes in human tissues. Evidence for species heterogeneity and implications for human pharmacology Anesthesiology 81 1994 1235 1244
31. V. Lemarchandel, J. Ghysdael, V. Mignotte, C. Rahuel, and P.H. Romeo GATA and Ets cis-acting sequences mediate megakaryocyte-specific expression Mol Cell Biol 13 1993 668 676
32. C. Rodriguez-Antona, R. Bort, R. Jover, N. Tindberg, M. Ingelman-Sundberg, and M.J. Gomez-Lechon Transcriptional regulation of human CYP3A4 basal expression by CCAAT enhancer-binding protein α and hepatocyte nuclear factor-3 gamma Mol Pharmacol 63 2003 1180 1189
33. S. Deveaux, S. Cohen-Kaminsky, R.A. Shivdasani, N.C. Andrews, A. Filipe, and I. Kuzniak p45 NF-E2 regulates expression of thromboxane synthase in megakaryocytes Embo J 16 1997 5654 5661
34. V. Mignotte, J.F. Eleouet, N. Raich, and P.H. Romeo Cis- and trans-acting elements involved in the regulation of the erythroid promoter of the human porphobilinogen deaminase gene Proc Natl Acad Sci USA 86 1989 6548 6552
35. A. Tugores, S.T. Magness, and D.A. Brenner A single promoter directs both housekeeping and erythroid preferential expression of the human ferrochelatase gene J Biol Chem 269 1994 30789 30797
36. P.J. Amrolia, L. Ramamurthy, D. Saluja, N. Tanese, S.M. Jane, and J.M. Cunningham The activation domain of the enhancer binding protein p45NF-E2 interacts with TAFII130 and mediates long-range activation of the α- and beta-globin gene loci in an erythroid cell line Proc Natl Acad Sci USA 94 1997 10051 10056
37. X. Cheng, M.J. Reginato, N.C. Andrews, and M.A. Lazar The transcriptional integrator CREB-binding protein mediates positive cross talk between nuclear hormone receptors and the hematopoietic bZip protein p45/NF-E2 Mol Cell Biol 17 1997 1407 1416
38. H.L. Hung, A.Y. Kim, W. Hong, C. Rakowski, and G.A. Blobel Stimulation of NF-E2 DNA binding by CREB-binding protein (CBP)-mediated acetylation J Biol Chem 276 2001 10715 10721
39. K. Igarashi, K. Kataoka, K. Itoh, N. Hayashi, M. Nishizawa, and M. Yamamoto Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins Nature 367 1994 568 572
40. R.A. Shivdasani, M.F. Rosenblatt, D. Zucker-Franklin, C.W. Jackson, P. Hunt, and C.J. Saris Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development Cell 81 1995 695 704
41. R.A. Shivdasani, and S.H. Orkin Erythropoiesis and globin gene expression in mice lacking the transcription factor NF-E2 Proc Natl Acad Sci USA 92 1995 8690 8694
42. K.J. Kotkow, and S.H. Orkin Complexity of the erythroid transcription factor NF-E2 as revealed by gene targeting of the mouse p18 NF-E2 locus Proc Natl Acad Sci USA 93 1996 3514 3518
43. J.A. Shavit, H. Motohashi, K. Onodera, J. Akasaka, M. Yamamoto, and J.D. Engel Impaired megakaryopoiesis and behavioral defects in mafG-null mutant mice Genes Dev 12 1998 2164 2174
44. K. Onodera, J.A. Shavit, H. Motohashi, M. Yamamoto, and J.D. Engel Perinatal synthetic lethality and hematopoietic defects in compound mafG:mafK mutant mice Embo J 19 2000 1335 1345
45. S.F. Tsai, D.I. Martin, L.I. Zon, A.D. D'Andrea, G.G. Wong, and S.H. Orkin Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells Nature 339 1989 446 451
46. T. Evans, and G. Felsenfeld The erythroid-specific transcription factor Eryf1: a new finger protein Cell 58 1989 877 885
47. L. Pevny, M.C. Simon, E. Robertson, W.H. Klein, S.F. Tsai, and V. D'Agati Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1 Nature 349 1991 257 260
48. M.J. Weiss, G. Keller, and S.H. Orkin Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells Genes Dev 8 1994 1184 1197
49. Y. Fujiwara, C.P. Browne, K. Cunniff, S.C. Goff, and S.H. Orkin Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1 Proc Natl Acad Sci USA 93 1996 12355 12358