Upregulated hoxC4 induces CD14 expression during the differentiation of acute promyelocytic leukemia cells

Leukemia and Lymphoma

Volumn 46, Issue 7, 2005, Pages 1061-1066

  Kim, Dong Yeon ^a   Choi, So Jung ^a   Kim, Sun Hee ^a   Chung, Hee Yong ^b   Yi, Seok ^c   Kim, Dong Wook ^c   Kim, Chun Chu ^c   Han, Tae Hee ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Hanyang University   (South Korea)

^c The Catholic University of Korea   (South Korea)

Author keywords

Acute promyelocytic leukemia; ATRA; CD14; Hox; NB4 cells

Indexed keywords

CD11B ANTIGEN; CD14 ANTIGEN; HOMEODOMAIN PROTEIN; HOX PROTEIN; HOXA9 PROTEIN; HOXB7 PROTEIN; HOXC4 PROTEIN; HYBRID PROTEIN; PROMYELOCYTIC LEUKEMIA PROTEIN; RETINOIC ACID; RETINOIC ACID RECEPTOR ALPHA; RETROVIRUS VECTOR; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE CLUSTER; GENE EXPRESSION REGULATION; GENETIC TRANSDUCTION; HOMEOBOX; HUMAN; HUMAN CELL; LEUKEMIA CELL; LEUKEMOGENESIS; PHENOTYPIC VARIATION; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; REPRODUCIBILITY; TRANSCRIPTION REGULATION; UPREGULATION;

ANTIGENS, CD14; ANTINEOPLASTIC AGENTS; BONE MARROW CELLS; CELL DIFFERENTIATION; GENE EXPRESSION REGULATION, LEUKEMIC; HOMEODOMAIN PROTEINS; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; NEOPLASM PROTEINS; ONCOGENE PROTEINS, FUSION; PROMOTER REGIONS (GENETICS); TRETINOIN; U937 CELLS; UP-REGULATION;

EID: 22144497814     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.1080/10428190500102589     Document Type: Article

References (18)

1. Thorsteinsdottir U, Sauvageau G, Humphries RK. Hox homeobox genes as regulators of normal and leukemic hematopoiesis. Hematol Oncol Clin N Am 1997;11:1221-1237.
2. Hatano M, Roberts CW, Minden M, Crist WM, Korsmeyer SJ. Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia. Science 1991(5);253:79-82.
3. Perkins A, Kongsuwan K, Visvader J, Adams JM, Cory S. Homeobox gene expression plus autocrine growth factor production elicits myeloid leukemia. Proc Nat Acad Sci USA 1990;87:8398-8402.
4. He LZ, Merghoub T, Pandolfi PP. In vivo analysis of the molecular pathogenesis of acute promyelocytic leukemia in the mouse and its therapeutic implications. Oncogene 1999;20:5278-5292.
5. Ball HJ, Melnick A, Shaknovich R, Kohanski RA, Licht JD. The promyelocytic leukemia zinc finger (PLZF) protein binds DNA in a high molecular weight complex associated with cdc2 kinase. Nucleic Acids Res 1999;27:4106-4113
6. Warrel RP Jr, de The H, Wang ZY, Degos L. Acute promyelocytic leukemia. New Engl J Med 1993;329:177-189.
7. Park DJ, Chumakov AM, Vuong PT, Chih DY, Gombart AF, Miller WH Jr, Koeffler HP. CCAAT/enhancer binding protein epsilon is a potential retinoid target gene in acute promyelocytic leukemia treatment. J Clin Invest 1999;103:1399-1408.
8. Casini T, Pelicci PG. A function of p21 during promyelocytic leukemia cell differentiation independent of CDK inhibition and cell cycle arrest. Oncogene 1999;18:3235-3243.
9. Marshall H, Morrison A, Studer M, Popperl H, Krumlauf R. Retinoids and Hox genes. FASEB J 1996;10:969-978.
10. Pan Z, Hetherington CJ, Zhang DE. CCAAT/enhancer-binding protein activates the CD14 promoter and mediates transforming growth factor beta signaling in monocyte development. J Biol Chem 1999;274:23242-23248.
11. Schnabel CA, Jacobs Y, Cleary ML. HoxA9-mediated immortalization of myeloid progenitors requires functional interactions with TALE cofactors Pbx and Meis. Oncogene 2000;19:608-616.
12. Lill MC, Fuller JF, Herzig R, Crooks GM, Gasson JC. The role of the Homeobox gene, Hox B7, in human myelomonocytic differentiation. Blood 1995;85:692-697.
13. Choi SJ, Park SY, Han TH. 14-3-3tau associates with and activates the MEF2D transcription factor during muscle cell differentiation. Nucleic Acids Res 2001;29:2836-2842.
14. Wotton D, Lo RS, Lee S, Massague J. A Smad transcriptional corepressor. Cell 1999;97:29-39.
15. Lanotte M, Martin-Thouvenin V, Najman S, Balerini P, Valensi F, Berger R. NB4, a maturation inducible cell line with t(15;17) marker isolated from a human acute promyelocytic leukemia (M3). Blood 1991;77:1080-1086.
16. Wright SD, Ramos RA, Tobias PS, Ulevitch RJ, Mathison JC. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 1990;249:1431-1433.
17. Thompson A, Quinn MF, Grimwade D, O'Neill CM, Ahmed MR, Grimes S, McMullin MF, Cotter F, Lappin TRJ. Global down-regulation of Hox gene expression in PML-RARα+ acute promyelocytic leukemia identified by small-array real-time PCR. Blood 2003;101:1558-1565.
18. Zhang DH, Hetherington CJ, Tan S, Dziennis SE, Gonzalez DA, Chen HM, Tenen DG. Sp1 is a critical factor for the monocytic specific expression of human CD14. J Biol Chem 1994;269:11425-11434.