Is the end-game penetration (of the airway)?

Critical Care Medicine

Volumn 33, Issue 7, 2005, Pages 1654-1655

  Lipman, Jeffrey ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Antibiotics; Linezolid; Methicillin resistant staphylococcus aureus; Microdialysis; Pharmacokinetics; Ventilator associated pneumonia

Indexed keywords

ANTIBIOTIC AGENT; DALFOPRISTIN PLUS QUINUPRISTIN; DAPTOMYCIN; LINEZOLID; METICILLIN; PENICILLIN G; RIFAMPICIN; TELAVANCIN; TIGECYCLINE; UNCLASSIFIED DRUG; VANCOMYCIN;

CONCENTRATION RESPONSE; EDITORIAL; HUMAN; INTENSIVE CARE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MICRODIALYSIS; MINIMUM INHIBITORY CONCENTRATION; PENICILLIN RESISTANCE; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; VENTILATOR ASSOCIATED PNEUMONIA;

EID: 22144480306     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000170183.83774.F6     Document Type: Editorial

References (16)

1. Cunha BA: Nosocomial pneumonia. Diagnostic and therapeutic considerations. Med Clin North Am 2001; 85:79-114
2. Cosgrove SE, Sakoulas G, Perencevich EN, et al: Comparison of mortality associated with methicillin-resistant and methicillin-susceptible Staphylococcus aureus bacteremia: A meta-analysis. Clin Infect Dis 2003; 36:53-59
3. Nathwani D, Tillotson GS: Vancomycin for Staphylococcus aureus therapy of respiratory tract infections: The end of an era? Int J Antimicrob Agents 2003; 21:521-524
4. Cruciani M, Gatti G, Lazzarini L, et al: Penetration of vancomycin into human lung tissue. J Antimicrob Chemother 1996; 38:865-869
5. Finder M, Bellomo R, Lipman J: Pharmacological principles of antibiotic prescription in the critically ill. Anaesth Intensive Care 2002; 30:134-144
6. Gous AG, Dance MD, Lipman J, et al: Changes in vancomycin pharmacokinetics in critically ill infants. Anaesth Intensive Care 1995; 23:678-682
7. Bodi M, Ardanuy C, Olona M, et al: Therapy of ventilator-associated pneumonia: The Tarragona strategy. Clin Microbiol Infect 2001; 7:32-33
8. Kollef M, Rello J, Cammarata S, et al: Clinical cure and survival in Gram-positive ventilator-associated pneumonia: Retrospective analysis of two double-blind studies comparing linezolid with vancomycin. Intensive Care Medicine 2004; 30:388-394
9. MacGowan AP: Pharmacokinetic and pharmacodynamic profile of linezolid in healthy volunteers and patients with Gram-positive infections. J Antimicrob Chemother 2003; 51(Suppl 2):ii17-25
10. Stalker DJ, Jungbluth GL: Clinical pharmacokinetics of linezolid, a novel oxazolidinone antibacterial. Clin Pharmacokinet 2003; 42:1129-1140
11. Whitehouse T, Cepeda JA, Shulman R, et al: Pharmacokinetic studies of linezolid and teicoplanin in the critically ill. J Antimicrob Chemother 2005; 55:333-340
12. Boselli E, Breilh D, Rimmelé T, et al: Pharmacokinetics and intrapulmonary concentrations of linezolid administered to critically ill patients with ventilator-associated pneumonia. Crit Care Med 2005; 33:1529-1533
13. Cazzola M, Matera MG, Noschese P: Parenteral antibiotic therapy in the treatment of lower respiratory tract infections. Strategies to minimize the development of antibiotic resistance. Pulm Pharmacol Ther 2000; 13:249-256
14. Muller M: Microdialysis in clinical drug delivery studies. Adv Drug Deliv Rev 2000; 45:255-269
15. Muller M, dela Pena A, Derendorf H: Issues in pharmacokinetics and pharmacodynamics of anti-infective agents: Distribution in tissue. Antimicrob Agents Chemother 2004; 48:1441-1453
16. Joukhadar C, Frossard M, Mayer BX, et al: Impaired target site penetration of beta-lactams may account for therapeutic failure in patients with septic shock. Crit Care Med 2001; 29:385-391