Histidine residue at position 234 of oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae simultaneously influences cyclization, rearrangement, and deprotonation reactions

ChemBioChem

Volumn 6, Issue 7, 2005, Pages 1177-1181

  Wu, Tung Kung ^a   Liu, Yuan Ting ^a   Chang, Cheng Hsian ^a  

^a NATIONAL CHIAO TUNG UNIVERSITY   (Taiwan)

Author keywords

Cyclization; Homology modeling; Oxidosqualene cyclase; Rearrangement; Sterols; Terpenoids

Indexed keywords

LANOSTEROL SYNTHASE; PROTEIN OXIDOSQUALENE LANOSTEROL CYCLASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CYCLIZATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN STRUCTURE; PROTON TRANSPORT; REACTION ANALYSIS; SACCHAROMYCES CEREVISIAE; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; CYCLIZATION; HISTIDINE; INTRAMOLECULAR TRANSFERASES; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; POLYMERASE CHAIN REACTION; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRITERPENES;

SACCHAROMYCES CEREVISIAE;

EID: 22144474720     PISSN: 14394227     EISSN: None     Source Type: Journal    
DOI: 10.1002/cbic.200500084     Document Type: Article

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