-
1
-
-
0031031440
-
Primary pulmonary hypertension
-
L.J. Rubin Primary pulmonary hypertension N. Engl. J. Med. 336 1997 111 117
-
(1997)
N. Engl. J. Med.
, vol.336
, pp. 111-117
-
-
Rubin, L.J.1
-
2
-
-
0033817459
-
Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension. the International PPH Consortium
-
K.B. Lane, R.D. Machado, M.W. Pauciulo, J.R. Thomson, J.A. Phillips 3rd, J.E. Loyd, W.C. Nichols, and R.C. Trembath Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension. The International PPH Consortium Nat. Genet. 26 2000 81 84
-
(2000)
Nat. Genet.
, vol.26
, pp. 81-84
-
-
Lane, K.B.1
MacHado, R.D.2
Pauciulo, M.W.3
Thomson, J.R.4
Phillips III, J.A.5
Loyd, J.E.6
Nichols, W.C.7
Trembath, R.C.8
-
3
-
-
0035163071
-
BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension
-
R.D. Machado, M.W. Pauciulo, J.R. Thomson, K.B. Lane, N.V. Morgan, L. Wheeler, J.A. Phillips 3rd, J. Newman, D. Williams, N. Galie, A. Manes, K. McNeil, M. Yacoub, G. Mikhail, P. Rogers, P. Corris, M. Humbert, D. Donnai, G. Martensson, L. Tranebjaerg, J.E. Loyd, R.C. Trembath, and W.C. Nichols BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension Am. J. Hum. Genet. 68 2001 92 102
-
(2001)
Am. J. Hum. Genet.
, vol.68
, pp. 92-102
-
-
MacHado, R.D.1
Pauciulo, M.W.2
Thomson, J.R.3
Lane, K.B.4
Morgan, N.V.5
Wheeler, L.6
Phillips III, J.A.7
Newman, J.8
Williams, D.9
Galie, N.10
Manes, A.11
McNeil, K.12
Yacoub, M.13
Mikhail, G.14
Rogers, P.15
Corris, P.16
Humbert, M.17
Donnai, D.18
Martensson, G.19
Tranebjaerg, L.20
Loyd, J.E.21
Trembath, R.C.22
Nichols, W.C.23
more..
-
4
-
-
0033623296
-
Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family
-
J.R. Thomson, R.D. Machado, M.W. Pauciulo, N.V. Morgan, M. Humbert, G.C. Elliott, K. Ward, M. Yacoub, G. Mikhail, P. Rogers, J. Newman, L. Wheeler, T. Higenbottam, J.S. Gibbs, J. Egan, A. Crozier, A. Peacock, R. Allcock, P. Corris, J.E. Loyd, R.C. Trembath, and W.C. Nichols Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family J. Med. Genet. 37 2000 741 745
-
(2000)
J. Med. Genet.
, vol.37
, pp. 741-745
-
-
Thomson, J.R.1
MacHado, R.D.2
Pauciulo, M.W.3
Morgan, N.V.4
Humbert, M.5
Elliott, G.C.6
Ward, K.7
Yacoub, M.8
Mikhail, G.9
Rogers, P.10
Newman, J.11
Wheeler, L.12
Higenbottam, T.13
Gibbs, J.S.14
Egan, J.15
Crozier, A.16
Peacock, A.17
Allcock, R.18
Corris, P.19
Loyd, J.E.20
Trembath, R.C.21
Nichols, W.C.22
more..
-
5
-
-
0037096836
-
Functional analysis of bone morphogenetic protein type II receptor mutations underlying primary pulmonary hypertension
-
N. Rudarakanchana, J.A. Flanagan, H. Chen, P.D. Upton, R. Machado, D. Patel, R.C. Trembath, and N.W. Morrell Functional analysis of bone morphogenetic protein type II receptor mutations underlying primary pulmonary hypertension Hum. Mol. Genet. 11 2002 1517 1525
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 1517-1525
-
-
Rudarakanchana, N.1
Flanagan, J.A.2
Chen, H.3
Upton, P.D.4
MacHado, R.5
Patel, D.6
Trembath, R.C.7
Morrell, N.W.8
-
6
-
-
0036735752
-
Functional heterogeneity of bone morphogenetic protein receptor-II mutants found in patients with primary pulmonary hypertension
-
A. Nishihara, T. Watabe, T. Imamura, and K. Miyazono Functional heterogeneity of bone morphogenetic protein receptor-II mutants found in patients with primary pulmonary hypertension Mol. Biol. Cell 13 2002 3055 3063
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 3055-3063
-
-
Nishihara, A.1
Watabe, T.2
Imamura, T.3
Miyazono, K.4
-
7
-
-
0041326610
-
Serotonin transporter inhibitors protect against hypoxic pulmonary hypertension
-
E. Marcos, S. Adnot, M.H. Pham, A. Nosjean, B. Raffestin, M. Hamon, and S. Eddahibi Serotonin transporter inhibitors protect against hypoxic pulmonary hypertension Am. J. Respir. Crit. Care Med. 168 2003 487 493
-
(2003)
Am. J. Respir. Crit. Care Med.
, vol.168
, pp. 487-493
-
-
Marcos, E.1
Adnot, S.2
Pham, M.H.3
Nosjean, A.4
Raffestin, B.5
Hamon, M.6
Eddahibi, S.7
-
8
-
-
0036014810
-
Is the serotonin transporter involved in the pathogenesis of pulmonary hypertension?
-
S. Eddahibi, B. Raffestin, M. Hamon, and S. Adnot Is the serotonin transporter involved in the pathogenesis of pulmonary hypertension? J. Lab. Clin. Med. 139 2002 194 201
-
(2002)
J. Lab. Clin. Med.
, vol.139
, pp. 194-201
-
-
Eddahibi, S.1
Raffestin, B.2
Hamon, M.3
Adnot, S.4
-
9
-
-
2442519344
-
Overexpression of the 5-hydroxytryptamine transporter gene: Effect on pulmonary hemodynamics and hypoxia-induced pulmonary hypertension
-
M.R. MacLean, G.A. Deuchar, M.N. Hicks, I. Morecroft, S. Shen, J. Sheward, J. Colston, L. Loughlin, M. Nilsen, Y. Dempsie, and A. Harmar Overexpression of the 5-hydroxytryptamine transporter gene: effect on pulmonary hemodynamics and hypoxia-induced pulmonary hypertension Circulation 109 2004 2150 2155
-
(2004)
Circulation
, vol.109
, pp. 2150-2155
-
-
MacLean, M.R.1
Deuchar, G.A.2
Hicks, M.N.3
Morecroft, I.4
Shen, S.5
Sheward, J.6
Colston, J.7
Loughlin, L.8
Nilsen, M.9
Dempsie, Y.10
Harmar, A.11
-
10
-
-
0034776773
-
Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension
-
S. Eddahibi, M. Humbert, E. Fadel, B. Raffestin, M. Darmon, F. Capron, G. Simonneau, P. Dartevelle, M. Hamon, and S. Adnot Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension J. Clin. Invest. 108 2001 1141 1150
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1141-1150
-
-
Eddahibi, S.1
Humbert, M.2
Fadel, E.3
Raffestin, B.4
Darmon, M.5
Capron, F.6
Simonneau, G.7
Dartevelle, P.8
Hamon, M.9
Adnot, S.10
-
11
-
-
2442696430
-
Serotonin-induced smooth muscle hyperplasia in various forms of human pulmonary hypertension
-
E. Marcos, E. Fadel, O. Sanchez, M. Humbert, P. Dartevelle, G. Simonneau, M. Hamon, S. Adnot, and S. Eddahibi Serotonin-induced smooth muscle hyperplasia in various forms of human pulmonary hypertension Circ. Res. 94 2004 1263 1270
-
(2004)
Circ. Res.
, vol.94
, pp. 1263-1270
-
-
Marcos, E.1
Fadel, E.2
Sanchez, O.3
Humbert, M.4
Dartevelle, P.5
Simonneau, G.6
Hamon, M.7
Adnot, S.8
Eddahibi, S.9
-
12
-
-
0006463359
-
Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region
-
K.P. Lesch, D. Bengel, A. Heils, S.Z. Sabol, B.D. Greenberg, S. Petri, J. Benjamin, C.R. Muller, D.H. Hamer, and D.L. Murphy Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region Science 274 1996 1527 1531
-
(1996)
Science
, vol.274
, pp. 1527-1531
-
-
Lesch, K.P.1
Bengel, D.2
Heils, A.3
Sabol, S.Z.4
Greenberg, B.D.5
Petri, S.6
Benjamin, J.7
Muller, C.R.8
Hamer, D.H.9
Murphy, D.L.10
-
13
-
-
4644295951
-
Primary pulmonary hypertension in children may have a different genetic background than in adults
-
E. Grunig, R. Koehler, G. Miltenberger-Miltenyi, R. Zimmermann, M. Gorenflo, D. Mereles, K. Arnold, B. Naust, H. Wilkens, A. Benz, A. von Hippel, H.E. Ulmer, W. Kubler, H.A. Katus, C.R. Bartram, D. Schranz, and B. Janssen Primary pulmonary hypertension in children may have a different genetic background than in adults Pediatr. Res. 56 2004 571 578
-
(2004)
Pediatr. Res.
, vol.56
, pp. 571-578
-
-
Grunig, E.1
Koehler, R.2
Miltenberger-Miltenyi, G.3
Zimmermann, R.4
Gorenflo, M.5
Mereles, D.6
Arnold, K.7
Naust, B.8
Wilkens, H.9
Benz, A.10
Von Hippel, A.11
Ulmer, H.E.12
Kubler, W.13
Katus, H.A.14
Bartram, C.R.15
Schranz, D.16
Janssen, B.17
-
14
-
-
0032971293
-
Induction of serotonin transporter by hypoxia in pulmonary vascular smooth muscle cells. Relationship with the mitogenic action of serotonin
-
S. Eddahibi, V. Fabre, C. Boni, M.P. Martres, B. Raffestin, M. Hamon, and S. Adnot Induction of serotonin transporter by hypoxia in pulmonary vascular smooth muscle cells. Relationship with the mitogenic action of serotonin Circ. Res. 84 1999 329 336
-
(1999)
Circ. Res.
, vol.84
, pp. 329-336
-
-
Eddahibi, S.1
Fabre, V.2
Boni, C.3
Martres, M.P.4
Raffestin, B.5
Hamon, M.6
Adnot, S.7
|