Pharmacokinetics and tissue distribution of d-alpha-tocopheryl succinate formulations following intravenous administration in the rat

Biopharmaceutics and Drug Disposition

Volumn 26, Issue 5, 2005, Pages 195-203

  Teng, Xiao Wei ^a   Davies, Neal M ^a   Fukuda, Chie ^a   Good, Renee L ^b   Fariss, Marc W ^b  

^a WASHINGTON STATE UNIVERSITY   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

Alpha tocopherol; Alpha tocopheryl hemisuccinate; Pharmacokinetics; Vitamin E; Vitamin E succinate

Indexed keywords

ALPHA TOCOPHEROL; ALPHA TOCOPHEROL SUCCINATE; LIPOSOME; MACROGOL 400;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CATHETER; CONTROLLED STUDY; DISTRIBUTION VOLUME; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG HALF LIFE; DRUG HYDROLYSIS; DRUG TISSUE LEVEL; JUGULAR VEIN; LIVER; LUNG; MALE; NONHUMAN; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SINGLE DRUG DOSE; TISSUE DISTRIBUTION;

ANIMALS; ANTIOXIDANTS; AREA UNDER CURVE; CHEMISTRY, PHARMACEUTICAL; HALF-LIFE; INJECTIONS, INTRAVENOUS; MALE; RATS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION; TOCOPHEROLS; VITAMIN E;

EID: 22144461361     PISSN: 01422782     EISSN: None     Source Type: Journal    
DOI: 10.1002/bdd.451     Document Type: Article

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