In vitro expression demonstrates impaired secretion of the γAsn319, Asp320 deletion variant fibrinogen

Thrombosis and Haemostasis

Volumn 94, Issue 1, 2005, Pages 53-59

  Kani, Satomi ^a   Terasawa, Fumiko ^a   Lord, Susan T ^b   Tozuka, Minoru ^a   Ota, Hiroyoshi ^a   Okumura, Nobuo ^a   Katsuyama, Tsutomu ^a  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

chain; Assembly; Dysfibrinogen; Pulse chase analysis; Secretion

Indexed keywords

ASPARAGINE; ASPARTIC ACID; FIBRINOGEN;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL LYSATE; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DENSITOMETRY; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBRINOGEN SYNTHESIS; GENE DELETION; GENETIC TRANSFECTION; GENETIC VARIABILITY; HUMAN; HYPOFIBRINOGENEMIA; IMMUNOBLOTTING; IN VITRO STUDY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN SECRETION;

ANIMALS; BLOTTING, WESTERN; CHO CELLS; CRICETINAE; DENSITOMETRY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBRINOGEN; FIBRINOGENS, ABNORMAL; GENE DELETION; GENETIC VECTORS; HETEROZYGOTE; HUMANS; IMMUNOASSAY; IMMUNOBLOTTING; KINETICS; METHIONINE; RECOMBINANT PROTEINS; TIME FACTORS; TRANSFECTION;

EID: 22144452576     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH05-02-0134     Document Type: Article

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