Interactions of macromolecules with salt ions: An electrostatic theory for the Hofmeister effect

Proteins: Structure, Function and Genetics

Volumn 61, Issue 1, 2005, Pages 69-78

  Zhou, Huan Xiang ^a  

^a Florida State University   (United States)

Author keywords

Debye H ckel theory; Hofmeister effect; Protein solubility; Protein stability; Salting out

Indexed keywords

AMINO ACID; AMMONIUM SULFATE; CARBOXYHEMOGLOBIN; CITRATE SODIUM; COLD SHOCK PROTEIN; HEMOGLOBIN; MAGNESIUM SULFATE; PEPTIDE; POTASSIUM CHLORIDE; PROTEIN; SODIUM CHLORIDE; SODIUM SULFATE; WATER;

ARTICLE; CRYSTALLIZATION; DEBYE HUCKEL THEORY; DIELECTRIC CONSTANT; ELECTRIC POTENTIAL; HOFMEISTER EFFECT; IONIC STRENGTH; MACROMOLECULE; MATHEMATICAL MODEL; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STABILITY; SALTING OUT; SEPARATION TECHNIQUE; SOLUBILITY; SOLVATION; SURFACE TENSION; THEORY;

ANIMALS; COLD; ELECTROSTATICS; HEMOGLOBINS; HORSES; IONS; MODELS, CHEMICAL; NONLINEAR DYNAMICS; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEINS; SALTS; SOLUBILITY;

EID: 22144448052     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.20500     Document Type: Article

References (44)

1. Hofmeister F. Zur Lehre von der Wirkung der Salze. Zweite Mittheilung. Arch Exp Pathol Pharmakol 1888;24:247-260.
2. Cohn EJ, Ferry JD. Interactions of proteins with ions and dipolar ions. In: Cohn EJ and Edsall JT, editors. Proteins, amino acids and peptides as ions and dipolar ions. New York: Reinhold Publishing Corporation; 1943. p 586-622.
3. Nandi PK, Robinson DR. Effects of salts on the free energy of the peptide group. J Am Chem Soc 1972;94:1299-1308.
4. Green AA. Studies in the physical chemistry of the proteins. VIII. The solubility of hemoglobin in concentrated salt solutions. A study of the salting-out of proteins. J Biol Chem 1931;93:495-516.
5. Green AA. Studies in the physical chemistry of the proteins. X. The solubility of hemoglobin in chlorides and sulphates of varying concentration. J Biol Chem 1932;95:47-66.
6. Baldwin RL. How Hofmeister ion interactions affect protein stability. Biophys J 1996;71:2056-2063.
7. Debye P, MacAulay IJ. Das Elektrische Feld Der Ionen Und Die Neutralsalzwirking. Physik Z 1925;131:22-29.
8. Kirkwood JG. The theoretical interpretation of the properties of solutions of dipolar ions. In: Cohn EJ, Edsall JT, editors. Proteins, amino acids and peptides as ions and dipolar ions. New York: Reinhold Publishing Corporation, 1943. p 586-622.
9. Kirkwood JG. Theory of solutions of molecules containing widely separated charges with special application to zwitterions. J Chem Phys 1934;2:351-361.
10. Tanford C, Kirkwood JG. Theory of protein titration curves. I. General equations for impenetrable spheres. J Am Chem Soc 1957;79:5333-5339.
11. Zhou H-X. Brownian dynamics study of the influences of electrostatic interaction and diffusion on protein-protein association kinetics. Biophys J 1993;64:1711-1726.
12. Collins KD, Washabaugh MW. The Hofmeister effect and the behavior of water at interfaces. Q. Rev. Biophys. 1985;18:323-422.
13. Onsager L, Samaris NNT. The surface tension of Debye-Hückel electrolytes. J Chem Phys 1934;2:528-536.
14. Wagner C. The surface tension of dilute solutions of electrolytes. Phys Z 1924;25:474-477.
15. Washabaugh MW, Collins KD. The systematic characterization by aqueous chromatography of solutes which affect protein stability. J Biol Chem 1986;261:12477-12485.
16. von Hippel PH, Wong K-Y. On the conformational stability of globular proteins. The effects of various electrolytes and nonelectrolytes on the thermal ribonuclease transition. J Biol Chem 1965;240:3909-3923.
17. Perl D, Schmid FX. Electrostatic stabilization of a thermophilic cold shock protein. J Mol Biol 2001;313:343-357.
18. Ramos CH, Baldwin RL. Sulfate anion stabilization of native ribonuclease A both by anion binding and by the Hofmeister effect. Protein Sci 2002;11:1771-1778.
19. Perez-Jimenez R, Godoy-Ruiz R, Ibarra-Molero B, Sanchez-Ruiz JM. The efficiency of different salts to screen charge interactions in proteins: A Hofmeister effect? Biophys J 2004;86:2414-2429.
20. Zhou H-X, Dong F. Electrostatic contributions to the stability of a thermophilic cold shock protein. Biophys J 2003;84:2216-2222.
21. Zhou H-X. Macromolecular electrostatic energy within the nonlinear Poisson-Boltzmann equation. J Chem Phys 1994;100:3152-3162.
22. Sharp KA, Honig B. Calculating total electrostatic energies with the nonlinear Poisson-Boltzmann equation. J Phys Chem 1990;94: 7684-7692.
23. Chen T, Hefter G, Buchner R. Dielectric spectroscopy of aqueous solutions of KCl and CsCl. J Phys Chem A 2003;107:4025-4031.
24. Madura JD, Briggs JM, Wade RC, Davis ME, Luty BA, Ilin A, Antosiewicz J, Gilson MK, Bagheri B, Scott LR, et al. Electrostatics and diffusion of molecules in solution: simulations with the University of Houston Brownian Dynamics program. Comput Phys Commun 1995;91:57-95.
25. Mueser TC, Rogers PH, Arnone A. Interface sliding as illustrated by the multiple quaternary structures of liganded hemoglobin. Biochemistry 2000;39:15353-15364.
26. Brooks BR, Bruccoleri RE, Olafson BD, States DJ, Swaminathan S, Karplus M. CHARMM: a program for macromolecular energy, minimization, and dynamics calculations. J Comput Chem 1983;4: 187-217.
27. Tanford C. Physical chemistry of macromolecules. New York: John Wiley & Sons, Inc.; 1961.
28. Gibbs JW. On the equilibrium of heterogeneous substances. In: Longley WR, Van Name RG, editors. The collected works of J. Willard Gibbs, 1st ed. pp. 434. New York: Longmans, Green and Co.; 1928.
29. Johansson K, Eriksson JC. γ and dγ/dτ measurements on aqueous-solutions of 1,1-electrolytes. J Colloid Interface Sci 1974;49:469-480.
30. Bhuiyan LB, Bratko D, Outhwaite CW. Electrolyte surface tension in the modified Poisson-Boltzmann approximation. J Phys Chem 1991;95:336-340.
31. Levin Y, Flores-Mena JE. Surface tension of strong electrolytes. Europhys Lett 2001;56:187-192.
32. Ohshima H, Matsubara H. Surface tension of electrolyte solutions. Colloid Polym Sci 2004;282:1044-1048.
33. Jarvis NL, Scheiman MA. Surface potentials of aqueous electrolyte solutions. J Phys Chem 1968;72:74-78.
34. Weissenborn PK, Pugh RJ. Surface tension of aqueous solutions of electrolytes: relationship with ion hydration, oxygen solubility, and bubble coalescence. J Colloid Interface Sci 1996;184:550-563.
35. Bostrom M, Williams DRM, Ninham BW. Surface tension of electrolytes: specific ion effects explained by dispersion forces. Langmuir 2001;17:4475-4478.
36. Zhou H-X. A Gaussian-chain model for treating residual charge-charge interactions in the unfolded state of proteins. Proc Natl Acad Sci USA 2002;99:3569-3574.
37. Dominy BN, Perl D, Schmid FX, Brooks CLr. The effects of ionic strength on protein stability: the cold shock protein family. J Mol Biol 2002;319:541-554.
38. Spencer DS, Xu K, Logan TM, Zhou H-X. Effects of pH, salt, and macromolecular crowding on the stability of FK506-binding protein: an integrated experimental and theoretical study. J Mol Biol 2005;351:219-232.
39. Chitra R, Smith PE. Molecular dynamics simulations of the properties of cosolvent solutions. J Phys Chem B 2000;104:5854-5864.
40. Kalra A, Tugcu N, Cramer SM, Garde S. 2001. Salting-in and salting-out of hydrophobic solutes in aqueous salt solutions. J Phys Chem B 105:6380-6386.
41. Hribar B, Southall NT, Vlachy V, Dill KA. How ions affect the structure of water. J Am Chem Soc 2002;124:12302-12311.
42. Jungwirth P, Tobias DJ. Ions at air/water interface. J Phys Chem B 2002;106:6361-6373.
43. Bhatt D, Newman J, Radke CJ. Molecular dynamics simulations of surface tensions of aqueous elelctrolytic solutions. J Phys Chem B 2004;108:9077-9084.
44. Mason PE, Neilson GW, Ednderby JE, Saboungi M-L, Dempsey CE, MacKerell ADJ, Brady JW. The structure of aqueous guanidinium chloride solution. J Am Chem Soc 2004;126:11462-11470.