The human eye (retina): A site of persistent HCMV infection?

Graefe's Archive for Clinical and Experimental Ophthalmology

Volumn 243, Issue 7, 2005, Pages 671-676

  Vogel, Jens Uwe ^a   Fleckenstein, Corinna ^a   Wagner, Mathias ^b   Gümbel, Hermann O C ^c   Theegarten, Dirk ^b   Cinatl Jr , Jindrich ^a   Doerr, Hans Wilhelm ^a  

^a GOETHE UNIVERSITY   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

^c Bundeswehrkrankenhaus Ulm ^*  (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS ANTIGEN; VIRUS DNA;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; AGED; ARTICLE; DISEASE SEVERITY; DNA EXTRACTION; EYE CANCER; EYE DISEASE; FEMALE; HUMAN; IATROGENIC DISEASE; IMMUNE DEFICIENCY; IMMUNOCYTOCHEMISTRY; IMMUNOPATHOLOGY; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RETINITIS; SERODIAGNOSIS; VIREMIA; VIRUS LATENCY; VIRUS REACTIVATION;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, VIRAL; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS RETINITIS; DNA, VIRAL; EYE ENUCLEATION; FEMALE; HIV SERONEGATIVITY; HUMANS; IMMEDIATE-EARLY PROTEINS; IMMUNOENZYME TECHNIQUES; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; RETINA; VIRUS ACTIVATION; VIRUS LATENCY;

EID: 22144444912     PISSN: 0721832X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00417-004-0965-0     Document Type: Article

References (47)

1. Allen A, Beeman HW, Christensen L (1957) Cytomegalic inclusion disease. Am Arch Opthalmol 57:90-99 1:STN:280:CyiD38jktVM%3D
2. d'Arminio Monforte A, Mainini F, Testa L, Vago L, Balotta L, Nebuloni M, Antinori S, Bini T, Moroni M (1997) Predictors of cytomegalovirus disease, natural history and autopsy findings in a cohort of patients with AIDS. AIDS 11:517-524 10.1097/00002030-199704000-00016
3. Bevan IS, Daw RA, Day PJ, Ala FA, Walker MR (1991) Polymerase chain reaction for detection of human cytomegalovirus infection in a blood donor population. Br J Haematol 78:94-99 1:CAS:528:DyaK3MXlsFansbY%3D
4. Bowen EF, Sabin CA, Wilson P, Griffiths PD, Davey CC, Johnson MA, Emery VC (1997) Cytomegalovirus (CMV) viraemia detected by polymerase chain reaction identifies a group of HIV-positive patients at high risk of CMV disease. AIDS 11:889-893 10.1097/00002030-199707000-00008
5. Chen R, Xiong S, Yang Y, Fu W, Wang Y, Ge J (2003) The relationship between human cytomegalovirus infection and atherosclerosis development. Mol Cell Biochem 249:91-96 10.1023/A:1024759311013
6. Cinatl J Jr, Vogel J-U, Cinatl J, Weber B, Rabenau H, Novak M, Kornhuber B, Doerr HW (1996) Long-term productive human cytomegalovirus infection of a human neuroblastoma cell line. Int J Cancer 65:90-96 10.1002/ (SICI)1097-0215(19960103)65:1<90::AID-IJC16>3.0.CO;2-M
7. Coskuncan NM, Jabs DA, Dunn JP, Haller JA, Green WR, Vogelsang GB, Santos GW (1994) The eye in bone marrow transplantation. VI. Retinal complications. Arch Ophthalmol 112:372-379 1:STN:280:ByuC2srot10%3D
8. Crippa F, Corey L, Chuang EL, Sale G, Boeckh M (2001) Virological, clinical, and ophthalmologic features of cytomegalovirus retinitis after hematopoietic stem cell transplantation. Clin Infect Dis 32:214-219 10.1086/318447
9. Döcke WD, Prösch S, Fietze E, Kimel V, Zuckermann H, Klug C, Syrbe U, Krüger DH, von Baehr R, Volk HD (1994) Cytomegalovirus reactivation and tumour necrosis factor. Lancet 343:268-269 10.1016/ S0140-6736(94)91116-9
10. Egbert PR, Pollard RB, Gallagher JG, Merigan TC (1980) Cytomegalovirus retinitis in immunosuppressed hosts. II. Ocular manifestations. Ann Intern Med 93:664-670 1:STN:280:Bi6C2MfjsFM%3D
11. Fish KN, Söderberg-Naucler C, Mills LK, Stenglein S, Nelson JA (1998) Human cytomegalovirus persistently infects aortic endothelial cells. J Virol 72:5661-5668 1:CAS:528:DyaK1cXjvFGlsL4%3D
12. Fish KN, Stenglein SG, Ibanez C, Nelson JA (1995) Cytomegalovirus persistence in macrophages and endothelial cells. Scand J Infect Dis Suppl 99:34-40 1:STN:280:BymB2cvhvVc%3D
13. Gallant JE, Moore RD, Richman DD, Keruly J, Chaisson RE (1992) Incidence and natural history of cytomegalovirus disease in patients with advanced human immunodeficiency virus disease treated with zidovudine. The Zidovudine Epidemiology Study Group. J Infect Dis 166:1223-1227 1:STN:280:ByyD2MnmvVI%3D
14. Ganly PS, Arthur C, Goldman JM, Schulenburg WE (1988) Foscarnet as treatment for cytomegalovirus retinitis following bone marrow transplantation. Postgrad Med J 64:389-391 1:STN:280:BiaD2s7mtFU%3D
15. Gonzalez CR, Wiley CA, Arevalo JF, Garcia RF, Kuppermann BD, Berry C, Freeman WR (1996) Polymerase chain reaction detection of cytomegalovirus and human immunodeficiency virus-1 in the retina of patients with acquired immune deficiency syndrome with and without cotton-wool spots. Retina 16:305-311 1:STN:280:ByiD3MfnslA%3D
16. Griscelli F, Barrois M, Chauvin S, Lastere S, Bellet D, Bourhis JH (2001) Quantification of human cytomegalovirus DNA in bone marrow transplant recipients by real-time PCR. J Clin Microbiol 39:4362-4369 10.1128/JCM.39.12.4362-4369.2001
17. Halary F, Amara A, Lortat-Jacob H, Messerle M, Delaunay T, Houles C, Fieschi F, Arenzana-Seisdedos F, Moreau JF, Dechanet-Merville J (2002) Human cytomegalovirus binding to DC-SIGN is required for dendritic cell infection and target cell trans-infection. Immunity 17:653-664 10.1016/ S1074-7613(02)00447-8
18. Heinemann MH (1992) Characteristics of cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome. Am J Med 92:12S-16S 10.1016/0002-9343(92)90331-5
19. Hoover DR, Peng Y, Saah A, Semba R, Detels RR, Rinaldo CR Jr, Phair JP (1996) Occurrence of cytomegalovirus retinitis after human immunodeficiency virus immunosuppression. Arch Ophthalmol 114:821-827 1:STN:280:BymB28bjtFc%3D
20. Jabs DA (1995) Ocular manifestations of HIV infection. Trans Am Ophthalmol Soc 93:623-683 1:STN:280:BymA2Mfnt1E%3D
21. Jabs DA, Van Natta ML, Kempen JH, Reed PP, Lim JI, Murphy RL, Hubbard LD (2002) Characteristics of patients with cytomegalovirus retinitis in the era of highly active antiretroviral therapy. Am J Ophthalmol 133:48-61 10.1016/S0002-9394(01)01322-8
22. Jiang HR, Lumsden L, Forrester JV (1999) Macrophages and dendritic cells in IRBP-induced experimental autoimmune uveoretinitis in B10RIII mice. Invest Ophthalmol Vis Sci 40:3177-3185 1:STN:280:DC%2BD3c%2Flt1ahsQ%3D%3D
23. Kercher LB, Mitchell M (2002) Persisting murine cytomegalovirus can reactivate and has unique transcriptional activity in ocular tissue. J Virol 76:9165-9175 10.1128/JVI.76.18.9165-9175.2002
24. Kondo K, Xu J, Mocarski ES (1996) Human cytomegalovirus latent gene expression in granulocyte-macrophage progenitors in culture and in seropositive individuals. Proc Natl Acad Sci USA 93:11137-11142 10.1073/ pnas.93.20.11137
25. Lu J, Huang XJ, Lu DP (2003) Cytomegalovirus retinitis after allogeneic bone marrow transplantation: A case report and literature review. Zhonghua Xue Ye Xue Za Zhi 24:312-315
26. Mendelson M, Monard S, Sissons P, Sinclair J (1996) Detection of endogenous human cytomegalovirus in CD34+ bone marrow progenitors. J Gen Virol 77:3099-3102 1:CAS:528:DyaK2sXhvVOguw%3D%3D
27. Miyamoto T, Gondo H, Miyoshi Y, Shigematsu H, Minematsu T, Takenaka K, Tanimoto K, Horiuchi T, Asano Y, Inaba S, Minamishima Y, Niho Y (1998) Early viral complications following CD34-selected autologous peripheral blood stem cell transplantation for non-Hodgkin's lymphoma. Br J Haematol 100:348-350 10.1046/j.1365-2141.1998.00572.x
28. Okamoto T, Okada M, Mori A, Saheki K, Takatsuka H, Wada H, Tamura A, Fujimori Y, Takemoto Y, Kanamaru A, Kakishita E (1997) Successful treatment of severe cytomegalovirus retinitis with foscarnet and intraocular injection of ganciclovir in a myelosuppressed unrelated bone marrow transplant patient. Bone Marrow Transplant 20:801-803 10.1038/ sj.bmt.1700967
29. Pepose JS, Holland GN, Nestor MS, Cochran AJ, Foos RY (1985) Acquired immune deficiency syndrome. Pathogenic mechanisms of ocular disease. Ophthalmology 92:472-484 1:STN:280:BiqB3MvptVc%3D
30. W Preiser S Buxbaum C Fleckenstein HW Doerr 2003 Measurement of CMV DNA levels and CMV-specific CD4+ lymphocyte counts in patient specimens: requirements for test quality and practibility in a routine diagnostic service S Prösch J Cinatl Jr M Scholz (eds) New aspects of CMV-related immunopathology Karger Basel, pp 133-148
31. Rao NA, Zhang J, Ishimoto S (1998) Role of retinal vascular endothelial cells in development of CMV retinitis. Trans Am Ophthalmol Soc 96:111-123 1:STN:280:DyaK1M3ovVGltw%3D%3D
32. Read RW, Zhang JA, Ishimoto SI, Rao NA (1999) Evaluation of the role of human retinal vascular endothelial cells in the pathogenesis of CMV retinitis. Ocul Immunol Inflamm 7:139-146 10.1076/ocii.7.3.139.4011
33. Saillour F, Bernard N, Dequae-Merchadou L, Marimoutou C, Journot V, Dabis F (1998) Predictive factors of occurrence of cytomegalovirus disease and impact on survival in the Aquitaine Cohort in France, 1985 to 1994. Groupe d'Epidemiologie Clinique du SIDA en Aquitaine. J Acquir Immune Defic Syndr Hum Retrovirol 17:171-178 1:STN:280:DyaK1c7jt1elsA%3D%3D
34. Scholz M, Doerr HW, Cinatl J Jr (2003) Human cytomegalovirus retinitis: pathogenicity, immune evasion and persistence. Trends Microbiol 11:171-178 10.1016/S0966-842X(03)00066-0
35. See RF, Rao NA (2002) Cytomegalovirus retinitis in the era of combined highly active antiretroviral therapy. Ophthalmol Clin North Am 15:529-536
36. Shinkai M, Bozzette SA, Powderly W, Frame P, Spector SA (1997) Utility of urine and leukocyte cultures and plasma DNA polymerase chain reaction for identification of AIDS patients at risk for developing human cytomegalovirus disease. J Infect Dis 175:302-308
37. Simmonds P, Zhang LQ, Watson HG, Rebus S, Ferguson ED, Balfe P, Leadbetter GH, Yap PL, Peutherer JF, Ludlam CA (1990) Hepatitis C quantification and sequencing in blood products, haemophiliacs, and drug users. Lancet 336:1469-1472 10.1016/0140-6736(90)93179-S
38. Skiest DJ (1999) Cytomegalovirus retinitis in the era of highly active antiretroviral therapy (HAART). Am J Med Sci 317:318-335 10.1097/ 00000441-199905000-00009
39. Song MK, Azen SP, Buley A, Torriani F, Cheng L, Chaidhawangul S, Ozerdem U, Scholz B, Freeman WR (2003) Effect of anti-cytomegalovirus therapy on the incidence of immune recovery uveitis in AIDS patients with healed cytomegalovirus retinitis. Am J Ophthalmol 136:696-702 10.1016/ S0002-9394(03)00335-0
40. Söderberg-Naucler C, Nelson JY (1999) Human cytomegalovirus latency and reactivation - a delicate balance between the virus and its host's immune system. Intervirology 42:314-321 10.1159/000053966
41. Speir E, Modali R, Huang ES, Leon MB, Shawl F, Finkel T, Epstein SE (1994) Potential role of human cytomegalovirus and p53 interaction in coronary restenosis. Science 265:391-394 1:CAS:528:DyaK2cXltVGks74%3D
42. Stanier P, Kitchen AD, Taylor DL, Tyms AS (1992) Detection of human cytomegalovirus in peripheral mononuclear cells and urine samples using PCR. Mol Cell Probes 6:51-58 1:STN:280:By2C1cnovFY%3D
43. Studies of ocular complications of AIDS Research Group in collaboration with the AIDS Clinical Trials Group (1997) Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial. 5. Clinical features of cytomegalovirus retinitis at diagnosis. Am J Ophthalmol 124:141-157
44. Sund F, Wahlberg J, Eriksson BM (2001) CMV disease in CMV-mismatched renal transplant recipients with prophylactic low dose valaciclovir. J Clin Virol 23:107-111 10.1016/S1386-6532(01)00213-X
45. Taylor-Wiedeman J, Sissons JG, Borysiewicz LK, Sinclair JH (1991) Monocytes are a major site of persistence of human cytomegalovirus in peripheral blood mononuclear cells. J Gen Virol 72:2059-2064 1:CAS:528:DyaK3MXmslaisLY%3D
46. Tufail A, Moe AA, Miller MJ, Wagar EA, Bruckner DA, Holland GN (1999) Quantitative cytomegalovirus DNA level in the blood and its relationship to cytomegalovirus retinitis in patients with acquired immune deficiency syndrome. Ophthalmology 106:133-141 10.1016/S0161-6420(99)90015-5
47. Wei LL, Park SS, Skiest DJ (2002) Prevalence of visual symptoms among patients with newly diagnosed cytomegalovirus retinitis. Retina 22:278-282 10.1097/00006982-200206000-00004