Comparative relaxant effects of YC-1 and DETA/NO on spontaneous contractions and the levels of cGMP of isolated pregnant rat myometrium

European Journal of Pharmacology

Volumn 517, Issue 3, 2005, Pages 240-245

  Demirkoprulu, Nihal ^a   Cetin, Meral ^a   Bagcivan, Ihsan ^a   Kaya, Tijen ^a   Soydan, Ahmet Serdar ^a   Karadas, Baris ^a   Cetin, Ali ^a  

^a CUMHURIYET UNIVERSITY   (Turkey)

Author keywords

DETA NO; Myometrium; Nitric oxide donor; Soluble guanylate cyclase activator; YC 1

Indexed keywords

1 BENZYL 3 (5 HYDROXYMETHYL 2 FURYL)INDAZOLE; CYCLIC GMP; DIETHYLENETRIAMINE NITRIC OXIDE; GUANYLATE CYCLASE; METHYLENE BLUE; NITRIC OXIDE DONOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; FEMALE; FETUS; ISOLATED ORGAN; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; RAT; UTERUS CONTRACTION; UTERUS HORN; UTERUS RELAXATION;

ANIMALS; CYCLIC GMP; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; INDAZOLES; MALE; METHYLENE BLUE; MUSCLE RELAXATION; MYOMETRIUM; NITRIC OXIDE DONORS; PREGNANCY; RATS; RATS, WISTAR; TIME FACTORS; TRIAZENES; UTERINE CONTRACTION;

EID: 22144440883     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.05.027     Document Type: Article

References (32)

1. K.K. Bradley, I.L. Buxton, J.E. Barber, T. Mcgaw, and M.E. Bradley Nitric oxide relaxes human myometrium by a cGMP-independent mechanism Am. J. Physiol. 275 1998 1668 1673
2. I. Buhimschi, C. Yallampalli, Y.L. Dong, and R.E. Garfield Involvement of a nitric oxide-cyclic guanosine monophosphate pathway in control of human uterine contractility during pregnancy Am. J. Obstet. Gynecol. 172 1995 1577 1584
3. I.L. Buxton, R.A. Kaiser, N.A. Malmquist, and S. Tichenor NO-induced relaxation of labouring and non-labouring human myometrium is not mediated by cyclic GMP Br. J. Pharmacol. 134 2001 206 214
4. A. Cetin, T. Kaya, N. Demirkoprulu, B. Karadas, B. Duran, and M. Cetin YC-1, a nitric oxide independent activator of soluble guanylate cyclase, inhibits the spontaneous contractions of isolated pregnant rat myometrium J. Pharm. Sci. 94 1 2004 19 24
5. s in human myometrium in term and preterm labor: a mechanism for parturition J. Clin. Endocrinol. Metab. 79 1994 1835 1839
6. J.K. Hennan, and J. Diamond Evidence that spontaneous contractile activity in the rat myometrium is not inhibited by NO-mediated increases in tissue levels of cyclic GMP Br. J. Pharmacol. 123 1998 959 967
7. H. Izumi, and R.E. Garfield Relaxant effects of nitric oxide and cyclic GMP on pregnant rat uterine longitudinal smooth muscle Eur. J. Obstet. Gynecol. Reprod. Biol. 60 1995 171 180
8. G.D. Jones, and L. Poston The role of endogenous nitric oxide synthesis in contractility of term or preterm human myometrium Br. J. Obstet. Gynaecol. 104 1997 241 245
9. D. Koesling, and A. Friebe Soluble guanylyl cyclase: structure and regulation Rev. Physiol., Biochem. Pharmacol. 135 1999 41 65
10. C.A. Koks, H.A. Brolmann, M.J. de Kleine, and P.A. Manger A randomized comparison of nifedipine and ritodrine for suppression of preterm labor Eur. J. Obstet. Gynecol. Reprod. Biol. 77 1998 171 176
11. K.A. Kuenzli, M.E. Bradley, and I.L. Buxton Cyclic GMP-independent effects of nitric oxide on guinea-pig uterine contractility Br. J. Pharmacol. 119 1996 737 743
12. K.A. Kuenzli, I.L. Buxton, and M.E. Bradley Nitric oxide regulation of monkey myometrial contractility Br. J. Pharmacol. 124 1998 63 68
13. C. Lees, S. Campbell, E. Jauniaux, R. Brown, B. Ramsay, D. Gibb, S. Moncada, and J.F. Martin Arrest of preterm labour and prolongation of gestation with glyceryl trinitrate, a nitric oxide donor Lancet 343 1994 1325 1326
14. C.G. Li, and M.J. Rand Nitric oxide and vasoactive intestinal polypeptide mediate non-adrenergic, non-cholinergic inhibitory transmission to smooth muscle of the rat gastric fundus Eur. J. Pharmacol. 191 1990 303 309
15. C.G. Li, and M.J. Rand Evidence that part of the NANC relaxant response of guinea-pig trachea to electrical field stimulation is mediated by nitric oxide Br. J. Pharmacol. 102 1991 91 94
16. T.M. Lincoln Cyclic GMP and mechanisms of vasodilatation Pharmacol. Ther. 41 1989 479 502
17. K.S. Lindeman, D.J. Forrester, C.A. Hirshman, and C.W. Emala Myometrial adenylyl cyclase protein decreases on the last day of pregnancy in the rat Biol. Reprod. 62 2000 1422 1426
18. Bernal A. Lopez, G.N. Europe-Finner, S. Phaneuf, and S.P. Watson Preterm labour: a pharmacological challenge Trends Pharmacol. Sci. 16 1995 129 133
19. S. Moncada, R.M. Palmer, and E.A. Higgs Nitric oxide: physiology, pathophysiology, and pharmacology Pharmacol. Rev. 43 1991 109 142
20. E.S. Natuzzi, P.C. Ursell, M. Harrison, C. Buscher, and R.K. Riemer Nitric oxide synthase activity in the pregnant uterus decreases at parturition Biochem. Biophys. Res. Commun. 194 1993 1 8
21. + 2 and mechanical transients in canine gastric smooth muscle J. Physiol. 445 1992 231 247
22. R.S. Pickard, P.H. Powell, and M.A. Zar The effect of inhibitors of nitric oxide biosynthesis and cyclic GMP formation on nerve-evoked relaxation of human cavernosal smooth muscle Br. J. Pharmacol. 104 1991 755 759
23. B. Ramsay, S.R. Sooranna, and M.R. Johnson Nitric oxide synthase activities in human myometrium and villous trophoblast throughout pregnancy Obstet. Gynecol. 87 1996 249 253
24. K. Schmidt, A. Schrammel, D. Koesling, and B. Mayer Molecular mechanisms involved in the synergistic activation of soluble guanylyl cyclase by YC-1 and nitric oxide in endothelial cells Mol. Pharmacol. 59 2001 220 224
25. S.M. Sladek, and J.M. Roberts Nitric oxide synthase activity in the gravid rat uterus decreases a day before the onset of parturition Am. J. Obstet. Gynecol. 175 1996 1661 1667
26. J.F. Telfer, F. Lyall, J.E. Norman, and I.T. Cameron Identification of nitric oxide synthase in human uterus Hum. Reprod. 10 1995 19 23
27. A.J. Thomson, J.F. Telfer, G. Kohnen, A. Young, I.T. Cameron, I.A. Greer, and J.E. Norman Nitric oxide synthase activity and localization do not change in uterus and placenta during human parturition Hum. Reprod. 12 1997 2546 2552
28. C.P. Weiner, R.G. Knowles, S.E. Nelson, and L.D. Stegink Pregnancy increases guanosine 3′,5′monophosphate in the myometrium independent of nitric oxide synthesis Endocrinology 135 1994 2473 2478
29. E.W. Wolf, A. Banerjee, J. Soble-Smith, F.C. Dohan Jr., R.P. White, and J.T. Robertson Reversal of cerebral vasospasm using an intrathecally administered nitric oxide donor J. Neurosurg. 89 2 1998 279 288
30. C.C. Wu, F.N. Ko, S.C. Kuo, F.Y. Lee, and C.M. Teng YC-1 inhibited human platelet aggregation through NO-independent activation of soluble guanylate cyclase Br. J. Pharmacol. 116 1995 1973 1978
31. C. Yallampalli, R.E. Garfield, and M. Byam-Smith Nitric oxide inhibits uterine contractility during pregnancy but not during delivery Endocrinology 133 1993 1899 1902
32. C. Yallampalli, H. Izumi, M. Byam-Smith, and R.E. Garfield An l-arginine-nitric oxide-cyclic guanosine monophosphate system exists in the uterus and inhibits contractility during pregnancy Am. J. Obstet. Gynecol. 170 1994 175 185