Repeated ovarian stimulations induce oxidative damage and mitochondrial DNA mutations in mouse ovaries

Annals of the New York Academy of Sciences

Volumn 1042, Issue , 2005, Pages 148-156

  Chao, Hsiang Tai ^a   Lee, Shu Yu ^b   Lee, Horng Mo ^b   Liao, Tien Ling ^b   Wei, Yau Huei ^c   Kao, Shu Huei ^b  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Aging; mtDNA mutations; Oocyte; Ovarian stimulation; Oxidative damage

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; CARBONYL DERIVATIVE; CARBONYL PROTEIN; GONADOTROPIN; LIPID PEROXIDE; MITOCHONDRIAL DNA; PEPTIDE FRAGMENT; UNCLASSIFIED DRUG;

ADOLESCENT; AGING; ANEUPLOIDY; ANIMAL CELL; CELL FUNCTION; CONFERENCE PAPER; CONGENITAL MALFORMATION; DNA DAMAGE; EMBRYO; EMBRYO MORTALITY; EMBRYO TRANSFER; FEMALE; FERTILITY; INTRAUTERINE GROWTH RETARDATION; MITOCHONDRION; MOUSE; MUTATION; NONHUMAN; OOCYTE; OOCYTE COMPETENCE; OVARY; OVARY HYPERSTIMULATION; OXIDATIVE STRESS; SUPEROVULATION;

EID: 22044450684     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1338.016     Document Type: Conference Paper

References (18)

1. BOLAND, M.P., D. GOULDING & J.F. ROCHE. 1991. Alternative gonadotropins for super-ovulation in cattle. Theoriogenology 35: 5-17.
2. McKIERNAN, S. & B. BAVISTER. 1998. Gonadotropin stimulation of donor females decreases post-implantation viability of cultured one-cell hamster embryos. Hum. Reprod. 13: 724-729.
3. VOGEL, R. & H. SPIELMANN. 1992. Genotoxic and embryotoxic effects of gonadotropin-hyperstimulated ovulation of murine oocytes and preimplantation embryos, and term fetuses. Reprod. Toxicol. 6: 329-333.
4. MAILHES, J., F. MARCHETTI & D. YOUNG. 1995. Synergism between gonadotropins and vinblastine relative to the frequencies of metaphase I, diploid and aneuploid mouse oocytes. Mutagenesis 10: 185-188.
5. MA, S., D. KALOUSEK, B. YUEN & Y. MOON. 1997. Investigation of effects of pregnant mare serum gonadotropin (PMSG) on the chromosomal complement of CD-1 mouse embryos. J. Assist. Reprod. Genet. 14: 162-169.
6. DE BOER, P., F. VAN DER HOEVEN, E. WOLTERS & J. MATTHEIJ. 1991. Embryo loss, blastomere development and chromosomal constitution after human chorionic gonadotropin-induced ovulation in mice and rats with regular cycles. Gynecol. Obstet. Invest. 32: 200-205.
7. NAVOT, D., P.A. BERGH, M.A. WILLIAMS, et al. 1991. Poor oocyte quality rather than implantation failure as a cause of age-related decline in female fertility. Lancet 337: 1375-1377.
8. KLINE, J., A. KINNEY, B. LEVIN & D. WARBURTON. 2000. Trisomic pregnancy and earlier age menopause. Am. J. Hum. Genet. 67: 395-404.
9. COPPERMAN, A.B., C.E. SELICK, L. GRUNFELD, et al. 1995. Cumulative number and morphological score of embryos resulting in success: realistic expectations from in vitro fertilization-embryo transfer. Fertil. Steril. 64: 88-92.
10. VAN BLERKOM, J. & P. DAVIS. 2001. Differential effects of repeated ovarian stimulation on cytoplasmic and spindle organization in metaphase II mouse oocytes matured in vivo and in vitro. Hum. Reprod. 16: 757-764.
11. KEEFE, D.L., T. NIVEN-FAIRCHILD, S. POWELL & S. BURADAGUNTA. 1995. Mitochondrial deoxyribonucleic acid deletions in oocytes and reproductive aging in women. Fertil. Steril. 64: 577-583.
12. WAN, Q.H., H. Wu, T. FUJIHARA & S.G. FANG. 2004. Which genetic marker for which conservation genetics issue? Electrophoresis 25: 2165-2176.
13. SZOLTYS, M., J. GALAS, A. JABLONKA & Z. TABAROWSKI. 1994. Some morphological and hormonal aspects of ovulation and superovulation in the rat. J. Endocrinol. 141: 91-100.
14. ZIEBE, S., S. BANGSBOLL, K.L.T. SCHMIDT, et al. 2004. Embryo quality in natural versus stimulated IVF cycles. Hum. Reprod. 19: 1457-1460.
15. COMBELLES, C.M.H. & D.F. ALBERTINI. 2003. Assessment of oocyte quality following repeated gonadotropin stimulation in the mouse. Biol. Reprod. 68: 812-821.
16. WHELAN, J.G., III & N.F. VLAHOS. 2000. The ovarian hyperstimulation syndrome. Fertil. Steril. 73: 883-896.
17. TARÍN, J.J., S. PÉREZ-ALBALÁ & A. CANO. 2001. Cellular and morphological traits of ooytes retrieved from aging mice after exogenous ovarian stimulation. Biol. Reprod. 65: 141-150.
18. WILDING, M., B. DALE, M. MARINO, et al. 2001. Mitochondrial aggregation patterns and activity in human oocytes and preimplantation embryos. Hum. Reprod. 16: 909-917.