Transscleral implantation and neurophysiological testing of subretinal polyimide film electrodes in the domestic pig in visual prosthesis development

Journal of Neural Engineering

Volumn 2, Issue 1, 2005, Pages

  Sachs, Helmut G ^a   Schanze, Thomas ^b   Brunner, Ursula ^a   Sailer, Heiko ^c   Wiesenack, Christoph ^a  

^a UNIVERSITY HOSPITAL REGENSBURG   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTRODES; POLYIMIDES; PROSTHETICS;

HUMAN BLINDNESS; RETINITIS PIGMENTOSA; STIMULATION DEVICES; TRANSSCLERAL IMPLANTATION;

NEUROPHYSIOLOGY;

POLYIMIDE; IMIDE;

CONFERENCE PAPER; CONTROLLED STUDY; DOMESTIC PIG; ELECTROSTIMULATION; EVOKED VISUAL RESPONSE; IMPLANTATION; MICROELECTRODE; NEUROPHYSIOLOGY; NONHUMAN; PHOTOSTIMULATION; PRIORITY JOURNAL; RETINA; SCLERA; STIMULUS RESPONSE; SURGICAL TECHNIQUE; VISUAL PROSTHESIS; ANIMAL; ARTICLE; CHEMISTRY; ELECTRODE; EQUIPMENT; GENERAL MEDICAL AIDS; INSTRUMENTATION; METHODOLOGY; PHOTORECEPTOR; PHYSIOLOGY; SWINE; VISUAL CORTEX;

ANIMALIA; SUS SCROFA DOMESTICA;

ANIMALS; ELECTRIC STIMULATION; ELECTRODES, IMPLANTED; EQUIPMENT FAILURE ANALYSIS; EVOKED POTENTIALS, VISUAL; IMIDES; MICROELECTRODES; PHOTORECEPTORS; PROSTHESIS IMPLANTATION; SCLERA; SENSORY AIDS; SWINE; VISUAL CORTEX;

EID: 22044450029     PISSN: 17412560     EISSN: None     Source Type: Journal    
DOI: 10.1088/1741-2560/2/1/008     Document Type: Conference Paper

References (52)

1. Acland G M et al 2001 Gene therapy restores vision in a canine model of childhood blindness Nat. Genet. 28 92-5
2. Age-Related Eye Disease Study Research Group 2001 A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss AREDS Report No 8 Arch. Ophthalmol. 119 1417-36
3. Alteheld N, Roessler G, Vobig M and Walter P 2004 The retina implant - new approach to a visual prosthesis Biomed. Technol. 49 99-103
4. Aramant R B and Seiler M J 2004 Progress in retinal sheet transplantation Prog. Retin. Eye Res. 23 475-94
5. Bak M, Girvin J P, Hambrecht F T, Kufta C V, Loeb G E and Schmidt E M 1990 Visual sensations produced by intracortical microstimulation of the human occipital cortex Med. Biol. Eng. Comput. 28 257-9
6. Berson E L, Rosner B, Sandberg M A, Hayes K C, Nicholson B W, Weigel-DiFranco C and Willet W 1993 Vitamin A supplementation for retinitis pigmentosa Arch. Ophthalmol. 111 1456-9
7. Brindley G S 1973 Sensory effects of electrical stimulation of the visual and paravisual cortex in man Handbook of Sensory Physiology vol 7, ed R Jung, sect 3B R (Berlin: Springer) pp 583-94
8. Brindley G S and Lewin W S 1968 The sensations produced by electrical stimulation of the visual cortex J. Physiol. 196 479-93
9. Chow A Y and Chow V Y 1997 Subretinal electrical stimulation of the rabbit retina Neurosci. Lett. 225 13-6
10. Chow A Y, Chow V Y, Packo K H, Pollak J S, Peyman G A and Schuchard R 2004 The artificial silicon retina microchip for the treatment of vision loss from retinitis pigmentosa Arch. Ophthalmol. 122 460-9
11. Chow A Y, Pardue M T, Chow V Y, Peyman G A, Liang C, Perlman J I and Peachy N S 2001 Implantation of silicon chip microphotodiode arrays into the cat subretinal space IEEE Trans. Neural Syst. Rehabil. Eng. 9 86-95
12. Dobelle W H 2000 Artificial vision for the blind by connecting a television camera to the visual cortex ASAIO J. 46 3-9
13. Dobelle W H, Mladejovsky M G, Evans J K, Roberts T S and Girvin J P 1976 'Braille' reading by a blind volunteer by visual cortex stimulation Nature 259 111-2
14. Dobelle W H, Mladejovsky M G and Girvin J P 1974 Artificial vision for the blind: electrical stimulation of visual cortex offers hope for a functional prosthesis Science 183 440-4
15. Eckmiller R 1995 Towards retina implants for improvement of vision in humans with retinitis pigmentosa - challenges and first results Proc. WCNN 95 vol 1 (Washington, DC: INNS Press) pp 228-33
16. Eckmiller R 1997 Learning retina implants with epiretinal contacts. Ophthalmic. Res. 29 281-9
17. Eckmiller R et al 1994 Final Report of the Feasibility Study for a Neurotechnology Program Neurotechnology Report ed Eckmiller R (Bonn, Germany: BMBF)
18. Gekeler F, Kobuch K, Schwahn H N, Stett A, Shinoda K and Zrenner E 2004 Subretinal electrical stimulation of the rabbit retina with acutely implanted electrode arrays Graefe's Arch. Clin. Exp. Ophthalmol. 242 587-96
19. Girvin J 1988 Current status of artificial vision by electrocortical stimulation Can. J. Neurol. Sci. 15 58-62
20. Grumet A E, Wyatt J L and Rizzo J F 2000 Multi electrode stimulation and recording in the isolated retina J. Neurosci. Methods 101 31-42
21. Haemmerle H, Kobuch K, Kohler K, Nisch W, Sachs H and Stelzle M 2002 Biostability of micro-photodiode arrays for subretinal implantation Biomaterials 23 797-804
22. Hesse L, Schanze T H, Wilms M and Eger M 2000 Implantation of retina stimulation electrodes and recording of electrical stimulation responses in the visual cortex of the cat Graefe's Arch. Clin. Exp. Ophthalmol. 238 840-5
23. Humayun M S et al 2003 Visual perception in a blind subject with a chronic microelectronic retinal prosthesis Vis. Res. 43 2573-81
24. Humayun M S, de Juan E, Dagnelie G, Greenberg R J, Propst R H and Phillips D H 1996 Visual perception elicited by electrical stimulation of retina in blind humans Arch. Ophthalmol. 114 40-6
25. Humayun M, Propst R, de Juan E, McCormick K and Hickingbotham D 1994 Bipolar surface electrical stimulation of the vertebrate retina Arch. Ophthalmol. 112 110-16
26. Ito N, Shirahata A, Yagi T, Matsushima T, Kawase K, Watanabe M and Uchikawa Y 1997 Development of artificial retina using cultured neural cells and photoelectric device: a study on electric current with membrane model ICONIP '97: Proc. 4th Int. Conf. on Neural Information Processing pp 124-7
27. Jensen R J, Rizzo J F, Ziv O R, Grumet A and Wyatt J 2003 Threshold for activation of rabbit ganglion cells with an ultrafine, extracellular microelectrode Invest. Ophthalmol. Vis. Sci. 44 3533-43
28. Krumpazsky H G and Klauss V 1996 Epidemiology of blindness and eye disease Ophthalmologica 210 1-84
29. Laube T H, Schanze T H, Brockmann C, Bolle I, Stieglitz T H and Bornfeld N 2003 Chronically implanted epidural electrodes in Göttinger minipigs allow function tests of epiretinal implants Graefe's Arch. Clin. Exp. Ophthalmol. 241 1013-9
30. Normann R A, Maynard E M, Guillory K S and Warren D J 1996 Cortical implants for the blind IEEE Spectr. 33 54-9
31. Normann R A, Maynard E M, Rousche P J and Warren D J 1999 A neural interface for a cortical vision prosthesis Vis. Res. 39 2577-87
32. Palanker D, Huie P, Vankov A, Aramant R, Seiler M, Fischman H, Marmor M and Blumenkranz M 2004 Migration of retinal cells through a perforated membrane: implications for a high-resolution prosthesis Invest. Ophthalmol. Vis. Sci. 45 3266-70
33. Peterman M C, Bloom D M, Lee C, Bent S F, Marmo M F, Blumenkranz M S and Fishman H A 2003 Localized neurotransmitter release for use in a prototype retinal interface Invest. Ophthalmol. Vis. Sci. 44 3144-9
34. Radtke N D, Aramant R B, Seiler M J, Petry H M and Pidwell D 2004 Vision change after sheet transplant of fetal retina with retinal pigment epithelium to a patient with retinitis pigmentosa Arch. Ophthalmol. 122 1159-65
35. Rizzo J F, Loewenstein J, Kelly S K, Shire D B, Herndon T and Wyatt J L 1999 Electrical stimulation of human retina with a microfabricated electrode array Invest. Ophthalmol. Vis. Sci. 40 S783
36. Rizzo J F and Wyatt J 1997 Prospects for a visual prosthesis Neuroscientist 3 251-62
37. Rizzo J F, Wyatt J, Humayun M, de Juan E, Liu W, Chow A, Eckmiller R, Zrenner E, Yagi T and Abrams G 2001 Retinal prosthesis: an encouraging first decade with major challenges ahead. Ophthalmolgica 108 13-4
38. Rizzo J F, Wyatt J, Loewenstein J, Kelly S and Shire D 2003a Methods and perceptual thresholds for short-term electrical stimulation of human retina with microelectrode arrays Invest. Ophthalmol. Vis. Sci. 44 5355-61
39. Rizzo J F, Wyatt J, Loewenstein J, Kelly S and Shire D 2003b Perceptual efficacy of electrical stimulation of human retina with a microelectrode array during short-term electrical trials Invest. Ophthalmol. Vis. Sci. 44 5362-9
40. Sachs H G and Gabel V P 2004 Retinal replacement - the development of microelectronic retinal prostheses - experience with subretinal implants and new aspects Graefe's Arch. Clin. Exp. Ophthalmol. 242 717-23
41. Sachs H G, Schanze T, Wilms M, Rentzos A, Brunner U, Gekeler F and Hesse L Subretinal implantation and testing of polyimide film electrodes in cats Graefe's Arch. Clin. Exp. Ophthalmol. at press (online December 2004)
42. Schanze T H, Greve N and Hesse L 2003 Towards the cortical representation of form and motion stimuli generated by a retina implant Graefe's Arch. Clin. Exp. Ophthalmol. 241 685-93
43. Schanze T, Wilms M, Eger M, Hesse L and Eckhorn R 2002 Activation zones in cat visual cortex evoked by electrical retina stimulation Graefe's Arch. Clin. Exp. Ophthalmol. 240 947-54
44. Schmidt E M, Bak M J, Hambrecht F T, Kufta C V, O'Rourke D K and Vallabhanath P 1996 Feasibility of a visual prosthesis for the blind based on intracortical microstimulation of the visual cortex Brain 119 507-22
45. Stieglitz T, Blau C, Beutel H, Keller R and Meyer J U 1997 Konzeption und Entwicklung von flexiblen stimulatorstrukturen innerhalb eines retina implant systems (Conception and development of flexible stimulator structures within a retinal implant system) Biomed. Technol. 42 (Suppl.) 458-9
46. Tassiker G E 1956 US Patent 2760783
47. Veraart C, Raftopoulos C, Mortimer J T, Delbeke J, Pins D, Michaux G, Vanlierde A, Parrini S and Wanet-Defalque M C 1998 Visual sensations produced by optic nerve stimulation using an implanted self-sizing spiral cuff electrode Brain Res. 813 181-6
48. Wyatt J and Rizzo J 1996 Ocular implants for the blind IEEE Spectr. 33 47-53
49. Wistow G, Bernstein S L, Wyatt M K, Ray S, Behal A, Touchman J W, Bouffard G, Smith D and Peterson K 2002 Expressed sequence tag analysis of human retina for the NEIBank Project: retbindin, an abundant, novel retinal cDNA and alternative splicing of other retina-preferred gene transcripts Mol. Vis. 15 196-204
50. Zrenner E 2002 Will retinal implants restore vision? Science 295 1022-5
51. Zrenner E et al 1997 The development of subretinal microphotodiodes for replacement of degenerated photoreceptors Ophthalmic Res. 29 269-80
52. Zrenner E, Stett A, Weiss S, Aramant R B, Guenther E, Kohler K, Miliczek K D, Seiler M J and Haemmerle H 1999 Can subretinal microphotodiodes successfully replace degenerated photoreceptors? Vis. Res. 39 2555-67