Neuropharmacological evaluation of diethylether extract and xanthones of Gentiana kochiana

Pharmacology Biochemistry and Behavior

Volumn 81, Issue 3, 2005, Pages 535-542

  Tomić, Mirko ^a   Tovilović, Gordana ^a   Butorović, Biljana ^a   Krstić, Dijana ^a   Janković, Teodora ^a   Aljančić, Ivana ^b   Menković, Nebojša ^c  

^a UNIVERSITY OF BELGRADE   (Serbia)

^b Institute for Chemistry   (Serbia)

^c Institute for Medicinal Plants Research   (Serbia)

Author keywords

Antidepressant activity; Behavioral tests; Gentaiana kochiana; MAO inhibitor; Rodents; Xanthones

Indexed keywords

1,7 DIHYDROXY 3,8 DIMETHOXYXANTHONE; 1,7,8 TRIHYDROXY 3 METHOXYXANTHONE; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; DOPAMINE RECEPTOR; ETHER; GENTIANA KOCHIANA EXTRACT; IMIPRAMINE; MICROSOME ENZYME; PLANT EXTRACT; SEROTONIN RECEPTOR; UNCLASSIFIED DRUG; XANTHONE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASSAY; BEHAVIOR; BRAIN; BRAIN MITOCHONDRION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG POTENCY; DRUG SCREENING; ENZYME ACTIVITY; ENZYME INHIBITION; EX VIVO STUDY; EXAMINATION; FORCED SWIMMING TEST; GENTIANA KOCHIANA; IC 50; IMMOBILIZATION; IN VITRO STUDY; MALE; MEDICINAL PLANT; MOBILIZATION; NERVE ENDING; NEUROPHARMACOLOGY; NONHUMAN; OPEN FIELD TEST; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; RAT; RODENT; SCORING SYSTEM; SEROTONIN UPTAKE; STEREOTYPY; SYNAPTOSOME; TISSUE PREPARATION;

GENTIANA; RODENTIA;

EID: 22044442694     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2005.03.019     Document Type: Article

References (34)

1. B. Baragatti, V. Calderone, L. Testai, E. Martinotti, S. Chericoni, and I. Morelli Vasodilator activity of crude methanolic extract of Gentiana kokiana Perr. et Song. (Gentianaceae) J Ethnopharmacol 79 2002 369 372
2. P. Blier, N. Haddjeri, and C. de Montigny Enhancement of 5-HT transmission by sustained administration of the reversible and selective MAO-A inhibitor befloxatone Biol Psychiatry 42 1997 67S
3. M. Brocco, A. Dekeyne, S. Veiga, S. Girardon, and M.J. Millan Induction of hyperlocomotion in mice exposed to a novel environment by inhibition of serotonin reuptake. A pharmacological characterization of diverse classes of antidepressant agents Pharmacol Biochem Behav 71 2002 667 680
4. S. Chericoni, L. Testai, V. Calderone, G. Flamini, P. Nieri, and I. Morelli The xanthones gentiacaulein and gentiakochianin are responsible for the vasodilator action of the roots of Gentiana kochiana Planta Med 69 2003 770 772
5. S. Dall'Acqua, G. Innocenti, G. Viola, A. Piovan, R. Caniato, and E.M. Cappelletti Cytotoxic compounds from Polygala vulgaris Chem Pharm Bull 50 2002 1499 1501
6. M.J. Detke, J. Johnson, and I. Lucki Acute and chronic antidepressive drug treatment in the rat forced swimming test model of depression Clin Psychopharmacol 5 1997 107 112
7. I. Fagervall, and S.B. Ross Inhibition of mono amine oxidase in monoaminergic neurones in the rat brain by irreversible inhibitors Biochem Pharmacol 35 1986 1381 1387
8. A.E. Felner, and P.C. Waldmeier Cumulative effects of irreversible MAO inhibitors in vivo Biochem Pharmacol 28 1979 995 1002
9. S. Ghosal, P.V. Sharma, R.K. Chaudhuri, and S.K. Bhattacharya Chemical constituents of gentianaceae: XIV. Tetraoxygenated and pentaoxygenated xanthones of Swertia purpurascens Wall J Pharm Sci 64 1975 80 83
10. A. Holt, D.F. Sharman, G.B. Baker, and M.M. Palcic A continuous spectrophotometric assay for monoamine oxidase and related enzymes in tissue homogenates Anal Biochem 244 1997 384 392
11. M. Jastrzebska-Wiesek, T. Librowski, R. Czarnecki, H. Marona, and G. Nowak Central activity of new xanthone derivatives with chiral center in some pharmacological tests in mice Pol J Pharmacol 55 2003 461 465
12. R. Jovanović-Dunjić Gentiana L M. Josifović Flore de la Republique Socialiste de Serbie V 1973 Academie Serbe des Sciences et des Arts Beograd
13. T. Kameyama, M. Nagasaka, and K. Yamada Effects of antidepressant drugs on a quickly-learned conditioned-suppression response in mice Neuropharmacology 24 1985 285 290
14. W. Mahabusarakam, J. Proudfoot, W. Taylor, and K. Croft Inhibition of lipoprotein oxidation by prenylated xanthones derived from mangostin Free Radic Res 33 2000 643 659
15. M.A.K. Markwell, S.M. Haas, L.L. Bieber, and N.E. Tolbert Modification of Lowry procedure to simplify protein determination in membrane and lipoprotein samples Anal Biochem 87 1978 206 210
16. D. Meltzer, and P.A. Fox Increases in spontaneous activity following intermittent imipramine administration Psychopharmacologia 21 1971 187 191
17. N. Menković, K. Šavikin-Fodulović, V. Bulatović, I. Aljančić, N. Juranić, and S. Macura Xanthones from Swertia punctata Phytochemistry 61 2002 415 420
18. S. Meszaros Evolutionary significance of xanthones in Gentianaceae: a reappraisal Biochem Syst Ecol 22 1994 85 94
19. J. Mogensen, T.K. Pedersen, and S. Holm Effects of chronic imipramine on exploration, locomotion, and food/water intake in rats Pharmacol Biochem Behav 47 1994 427 435
20. A.V. Muruganandam, S. Ghosal, and S.K. Bhattacharya The role of xanthones in the antidepressant activity of Hypericum perforatum involving dopaminergic and serotonergic systems Biog Amines 15 2000 553 567
21. N. Ohishi, T. Suzuki, T. Ogasawara, and K. Yagi Xanthone derivatives as inhibitors for monoamine oxidase J Mol Catal B Enzym 10 2000 291 294
22. V. Peres, and T.J. Nagem Trioxygenated naturally occurring xanthones Phytochemistry 44 1997 191 214
23. V. Peres, T.J. Nagem, and F.F. de Oliveira Tetraoxygenated naturally occurring xanthones Phytochemistry 55 2000 683 710
24. R.D. Porsolt, G. Anton, N. Blavet, and M. Jalfre Behavioural despair in rats: a new model sensitive to antidepressant treatments Eur J Pharmacol 47 1978 379 391
25. P. Rivaille, J. Massicot, M. Guyot, and V. Plouvier Les xanthones de Gentiana kochiana, Swertia decussata et S. perennis (gentianacees) Phytochemistry 8 1969 1533 1541
26. D. Schaufelberger, and K. Hostettmann Flavonoid glycosides and a bitter principle from Lomatogonium carinthiacum Phytochemistry 23 1984 787 789
27. O. Suzuki, Y. Katsumata, M. Oya, V.M. Chari, R. Klapfenberger, and H. Wagner Inhibition of type A and type B monoamine oxidase by isogentisin and its 3-O-glucoside Planta Med 39 1980 19 23
28. O. Suzuki, Y. Katsumata, M. Oya, V.M. Chari, B. Vermes, and H. Wagner Inhibition of type A and type B monoamine oxidases by naturally occurring xanthones Planta Med 42 1981 17 21
29. U. Thull, and B. Testa Screening of unsubstituted cyclic compounds as inhibitors of monoamine oxidases Biochem Pharmacol 47 1994 2307 2310
30. G. Tovilović, B. Butorović, T. Janković, D. Krstić, and M. Tomić Neurochemical screening of xanthones from Gentiana kochiana Third Conference AMAPSEEC, Nitra, Slovak Republik, IX; Book of Abstracts P 111 2004
31. R.E. Uncini Manganelli, S. Chericoni, and B. Baragatti Ethnopharmacobotany in Tuscany: plants used as antihypertensives Fitoterapia 71 Suppl. 1 2000 95 100
32. G.H. Vogel Drug discovery and evaluation-pharmacological assays 2002 Springer-Verlag Berlin
33. P.H. Yu, and L. Hertz Differential expression of type A and type B monoamine oxidase of mouse astrocytes in primary cultures J Neurochem 39 1982 1492 1495
34. J. Wenzel, and K. Kuschinsky Interactions between imipramine and morphine on motility in rats: possible relation to antidepressant effects? Pharmacopsychiatry 23 1990 274 278