Synthesis of 4-(1-oxo-isoindoline) and 4-(5,6-dimethoxy-1-oxo-isoindoline)- substituted phenoxypropanolamines and their β1-, β2-adrenergic receptor binding studies

Bioorganic Chemistry

Volumn 33, Issue 4, 2005, Pages 310-324

  Jindal, Dharam P ^a   Singh, Babita ^a   Coumar, Mohane S ^a,c   Bruni, Giancarlo ^b   Massarelli, Paola ^b  

^a PANJAB UNIVERSITY   (India)

^b UNIVERSITY OF SIENA   (Italy)

^c NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

Adrenergic blocking agents; Adrenergic receptor binding; 1 Oxo isoindoline; Atenolol; Phenoxypropanolamines; Propranolol

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; ATENOLOL; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; N [4 (2 HYDROXY 3 ISOPROPYLAMINOPROPOXY)PHENYL] 1 OXOISOINDOLINE; N [4 (2 HYDROXY 3 ISOPROPYLAMINOPROPOXY)PHENYL] 5,6 DIMETHOXY 1 OXOISOINDOLINE; N [4 (3 TERT BUTYLAMINO 2 HYDROXYPROPOXY)PHENYL] 1 OXOISOINDOLINE; N [4 (3 TERT BUTYLAMINO 2 HYDROXYPROPOXY)PHENYL] 5,6 DIMETHOXY 1 OXOISOINDOLINE; N [4 [2 HYDROXY 3 (3,4 DIMETHOXY N METHYLPHENYLETHYLAMINO)PROPOXY]PHENYL] 1 OXOISOINDOLINE; N [4 [2 HYDROXY 3 (3,4 DIMETHOXY N METHYLPHENYLETHYLAMINO)PROPOXY]PHENYL] 5,6 DIMETHOXY 1 OXOISOINDOLINE; N [4 [2 HYDROXY 3 (3,4 DIMETHOXYPHENYLETHYLAMINO)PROPOXY]PHENYL] 1 OXOISOINDOLINE; N [4 [2 HYDROXY 3 (3,4 DIMETHOXYPHENYLETHYLAMINO)PROPOXY]PHENYL] 5,6 DIMETHOXY 1 OXOISOINDOLINE; N [4 [2 HYDROXY 3 (4 METHYLPIPERAZINO)PROPOXY]PHENYL] 1 OXOISOINDOLINE; PHENOXYPROPANOLAMINE DERIVATIVE; PROPRANOLOL; UNCLASSIFIED DRUG;

ARTICLE; BETA ADRENERGIC RECEPTOR BLOCKING; DRUG ACTIVITY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SYNTHESIS; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR INTRINSIC ACTIVITY; SUBSTITUTION REACTION;

DIHYDROALPRENOLOL; INDOLES; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; PROPANOLAMINES; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-2;

EID: 21844450212     PISSN: 00452068     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bioorg.2005.05.001     Document Type: Article

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