Gender differences in trabecular bone architecture of the distal radius assessed with magnetic resonance imaging and implications for mechanical competence

Osteoporosis International

Volumn 16, Issue 9, 2005, Pages 1124-1133

  Hudelmaier, Martin ^a,b   Kollstedt, A ^c   Lochmuller E M ^b   Kuhn, V ^b   Eckstein, F ^a,b   Link, T M ^c,d  

^a PARACELSUS MEDICAL UNIVERSITY   (Austria)

^b UNIVERSITY OF MUNICH   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Dual X ray absorptiometry (DXA); High resolution MRI (hrMRI); Mechanical competence; Structural indices; Trabecular bone

Indexed keywords

FORMALDEHYDE;

AGED; ARTICLE; AUTOPSY; BONE DENSITY; FALLING; FEMALE; GENDER; HUMAN; HUMAN TISSUE; IN VIVO STUDY; MALE; METAPHYSIS; MULTIPLE REGRESSION; NUCLEAR MAGNETIC RESONANCE IMAGING; OSTEOPENIA; OSTEOPOROSIS; PARAMETER; PRIORITY JOURNAL; RADIUS FRACTURE; RISK ASSESSMENT; TRABECULAR BONE; X RAY ANALYSIS;

ACCIDENTAL FALLS; AGED; AGED, 80 AND OVER; ANTHROPOMETRY; BIOMECHANICS; BONE DENSITY; DENSITOMETRY, X-RAY; FEMALE; FRACTALS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; OSTEOPOROSIS; OSTEOPOROSIS, POSTMENOPAUSAL; RADIUS; SEX CHARACTERISTICS;

EID: 21844443988     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-004-1823-y     Document Type: Article

References (40)

1. Jensen GF, Christiansen C, Boesen J, Hegedus V, Transbol I (1982) Epidemiology of postmenopausal spinal and long bone fractures. A unifying approach to postmenopausal osteoporosis. Clin Orthop 166:75-81
2. Owen RA, Melton LJ III, Johnson KA, Ilstrup DM, Riggs BL (1982) Incidence of Colles' fracture in a North American community. Am J Public Health 72:605-607
3. Cuddihy MT, Gabriel SE, Crowson CS, O'Fallon WM, Melton LJ III (1999) Forearm fractures as predictors of subsequent osteoporotic fractures. Osteoporos Int 9:469-475
4. Spadaro JA, Werner FW, Brenner RA, Fortino MD, Fay LA, Edwards WT (1994) Cortical and trabecular bone contribute strength to the osteopenic distal radius. J Orthop Res 12:211-218
5. Augat P, Iida H, Jiang Y, Diao E, Genant HK (1998) Distal radius fractures: mechanisms of injury and strength prediction by bone mineral assessment. J Orthop Res 16:629-635
6. Gordon CL, Webber CE, Nicholson PS (1998) Relation between image-based assessment of distal radius trabecular structure and compressive strength. Can Assoc Radiol J 49:390-397
7. Wigderowitz CA, Paterson CR, Dashti H, McGurty D, Rowley DI (2000) Prediction of bone strength from cancellous structure of the distal radius: can we improve on DXA? Osteoporos Int 11:840-846
8. Wu C, Hans D, He Y, Fan B, Njeh CF, Augat P, Richards J, Genant HK (2000) Prediction of bone strength of distal forearm using radius bone mineral density and phalangeal speed of sound. Bone 26:529-533
9. Lochmüller EM, Lill CA, Kuhn V, Schneider E, Eckstein F (2002) Radius bone strength in bending, compression, and falling and its correlation with clinical densitometry at multiple sites. J Bone Miner Res 17:1629-1638
10. Hudelmaier M, Kuhn V, Lochmuller EM, Well H, Priemel M, Link TM, Eckstein F (2004) Can geometry-based parameters from pQCT and material parameters from quantitative ultrasound (QUS) improve the prediction of radial bone strength over that by bone mass (DXA)? Osteoporos Int 15:375-381
11. Muller ME, Webber CE, Bouxsein ML (2003) Predicting the failure load of the distal radius. Osteoporos Int 14:345-352
12. Ouyang X, Selby K, Lang P, Engelke K, Klifa C, Fan B, Zucconi F, Hottya G, Chen M, Majumdar S, Genant HK (1997) High-resolution magnetic resonance imaging of the calcaneus: age-related changes in trabecular structure and comparison with dual X-ray absorptiometry measurements. Calcif Tissue Int 60:139-147
13. Link TM, Majumdar S, Grampp S, Guglielmi G, van Kuijk C, Imhof H, Glueer C, Adams JE (1999) Imaging of trabecular bone structure in osteoporosis. Eur Radiol 9:1781-1788
14. Majumdar S, Link TM, Augat P, Lin JC, Newitt D, Lane NE, Genant HK (1999) Trabecular bone architecture in the distal radius using magnetic resonance imaging in subjects with fractures of the proximal femur. Magnetic Resonance Science Center and Osteoporosis and Arthritis Research Group. Osteoporos Int 10:231-239
15. Newitt DC, Majumdar S, van RB, von IG, Harris ST, Genant HK, Chesnut C, Garnero P, MacDonald B (2002) In vivo assessment of architecture and micro-finite element analysis derived indices of mechanical properties of trabecular bone in the radius. Osteoporos Int 13:6-17
16. Laib A, Newitt DC, Lu Y, Majumdar S (2002) New model-independent measures of trabecular bone structure applied to in vivo high-resolution MR images. Osteoporos Int 13:130-136
17. Majumdar S, Newitt D, Mathur A, Osman D, Gies A, Chiu E, Lotz J, Kinney J, Genant H (1996) Magnetic resonance imaging of trabecular bone structure in the distal radius: relationship with X-ray tomographic microscopy and biomechanics. Osteoporos Int 6:376-385
18. Link TM, Vieth V, Langenberg R, Meier N, Lotter A, Newitt D, Majumdar S (2003) Structure analysis of high-resolution magnetic resonance imaging of the proximal femur: in vitro correlation with biomechanical strength and BMD. Calcif Tissue Int 72:156-165
19. Link TM, Majumdar S, Augat P, Lin JC, Newitt D, Lu Y, Lane NE, Genant HK (1998) In vivo high-resolution MRI of the calcaneus: differences in trabecular structure in osteoporosis patients. J Bone Miner Res 13:1175-1182
20. Jiang Y, Zhao J, Augat P, Ouyang X, Lu Y, Majumdar S, Genant HK (1998) Trabecular bone mineral and calculated structure of human bone specimens scanned by peripheral quantitative computed tomography: relation to biomechanical properties. J Bone Miner Res 13:1783-1790
21. Majumdar S, Kothari M, Augat P, Newitt DC, Link TM, Lin JC, Lang T, Lu Y, Genant HK (1998) High-resolution magnetic resonance imaging: three-dimensional trabecular bone architecture and biomechanical properties. Bone 22:445-454
22. Hwang SN, Wehrli FW, Williams JL (1997) Probability-based structural parameters from three-dimensional nuclear magnetic resonance images as predictors of trabecular bone strength. Med Phys 24:1255-1261
23. Melton LJ III (1995) Epidemiology of fractures. In: Riggs BL, Melton LJ (eds) Osteoporosis: Etiology, diagnosis and management, 2nd edn. Lippincott-Raven, Philadelphia, 225-249
24. Riggs BL, Melton LJ III (1995) The worldwide problem of osteoporosis: insights afforded by epidemiology. Bone 17:505-511
25. MacIntyre NJ, Adachi JD, Webber CE (1999) Gender differences in normal age-dependent patterns of radial bone structure and density: a cross-sectional study using peripheral quantitative computed tomography. J Clin Densitom 2:163-173
26. World Health Organization (1994) Definition of osteoporosis. Technical Report Series 843
27. Glüer CC, Blake G, Lu Y, Blunt BA, Jergas M, Genant HK (1995) Accurate assessment of precision errors: how to measure the reproducibility of bone densitometry techniques. Osteoporos Int 5:262-270
28. Newitt DC, Van Rietbergen B, Majumdar S (2002) Processing and analysis of in vivo high-resolution MR images of trabecular bone for longitudinal studies: reproducibility of structural measures and micro-finite element analysis derived mechanical properties. Osteoporos Int 13:278-287
29. Hayes WC, Bouxsein ML (1997) Biomechanics of cortical and trabecular bone: Implications for assessment of fracture risk. In: Mow VC, Hayes WC (eds) Basic orthopaedic biomechanics, 2nd edn. Lippincott-Raven, Philadelphia, pp 69-111
30. van der Meulen MC, Jepsen KJ, Mikic B (2001) Understanding bone strength: size isn't everything. Bone 29:101-104
31. Muller ME, Webber CE, Bouxsein ML (2003) Predicting the failure load of the distal radius. Osteoporos Int 14:345-352
32. Lochmüller EM, Krefting N, Bürklein D, Eckstein F (2001) Effect of fixation, soft tissues, and scan projection on bone mineral measurements with dual energy X-ray absorptiometry (DXA). Calcif Tissue Int 68:140-145
33. Augat P, Reeb H, Claes LE (1996) Prediction of fracture load at different skeletal sites by geometric properties of the cortical shell. J Bone Miner Res 11:1356-1363
34. Edmondston SJ, Singer KP, Day RE, Breidahl PD, Price RI (1994) Formalin fixation effects on vertebral bone density and failure mechanics: an in vitro study of human and sheep vertebrae. Clin Biomech (Bristol Avon) 9:175-179
35. Grampp S, Genant HK, Mathur A, Lang P, Jergas M, Takada M, Glüer CC, Lu Y, Chavez M (1997) Comparisons of non-invasive bone mineral measurements in assessing age-related loss, fracture discrimination, and diagnostic classification. J Bone Miner Res 12:697-711
36. Myers ER, Sebeny EA, Hecker AT, Corcoran TA, Hipp JA, Greenspan SL, Hayes WC (1991) Correlations between photon absorption properties and failure load of the distal radius in vitro. Calcif Tissue Int 49:292-297
37. Njeh CF, Wu C, Fan B, Hans D, Fuerst T, He Y, Genant HK (2000) Estimation of wrist fracture load using phalangeal speed of sound: an in vitro study. Ultrasound Med Biol 26:1517-1523
38. Vieth V, Link TM, Lotter A, Persigehl T, Newitt D, Heindel W, Majumdar S (2001) Does the trabecular bone structure depicted by high-resolution MRI of the calcaneus reflect the true bone structure? Invest Radiol 36:210-217
39. Lin JC, Amling M, Newitt DC, Selby K, Srivastav SK, Delling G, Genant HK, Majumdar S (1998) Heterogeneity of trabecular bone structure in the calcaneus using magnetic resonance imaging. Osteoporos Int 8:16-24
40. Benhamou CL, Poupon S, Lespessailles E, Loiseau S, Jennane R, Siroux V, Ohley W, Pothuaud L (2001) Fractal analysis of radiographic trabecular bone texture and bone mineral density: two complementary parameters related to osteoporotic fractures. J Bone Miner Res 16:697-704