5-Fluorouracil selectively inhibits collagen synthesis

Plastic and Reconstructive Surgery

Volumn 116, Issue 1, 2005, Pages 209-221

  Bulstrode, Neil W ^b   Mudera, Vivek ^b   McGrouther, D Angus ^b   Grobbelaar, Adriaan O ^a   Cambrey, Alison D ^b  

^a MOUNT VERNON HOSPITAL   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; FLUOROURACIL; MESSENGER RNA; PROLINE; TRANSFORMING GROWTH FACTOR BETA1;

APONEUROSIS; ARTICLE; AUTOCRINE EFFECT; CELL SECRETION; COLLAGEN METABOLISM; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DUPUYTREN CONTRACTURE; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME RELEASE; EXTRACELLULAR MATRIX; FIBROBLAST; GENE EXPRESSION; HAND DISEASE; HUMAN; HUMAN CELL; ISOTOPE LABELING; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TENDON;

ANTIMETABOLITES; CELLS, CULTURED; COLLAGEN; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DUPUYTREN'S CONTRACTURE; EXTRACELLULAR MATRIX PROTEINS; FIBROBLASTS; FLUOROURACIL; GENE EXPRESSION; GRANULATION TISSUE; HUMANS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TENDONS; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 21744446860     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.PRS.0000169701.16509.D6     Document Type: Article

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