Acute myocardial infarction after sildenafil citrate ingestion

Annals of Pharmacotherapy

Volumn 39, Issue 7-8, 2005, Pages 1362-1364

  Kekilli, Murat ^a   Beyazit, Yavuz ^a   Purnak, Tugrul ^a   Dogan, Serkan ^a   Atalar, Enver ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Myocardial infarction, nitrate free patient; Sildenafil

Indexed keywords

ACETYLSALICYLIC ACID; CYCLIC GMP; HEPARIN; METOPROLOL; NITRATE; PHOSPHODIESTERASE V INHIBITOR; SILDENAFIL;

ACUTE HEART INFARCTION; ADULT; ARTICLE; AWARENESS; CASE REPORT; CLINICAL FEATURE; CORPUS CAVERNOSUM; HUMAN; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; NAUSEA; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; PHYSICAL EXAMINATION; PRIORITY JOURNAL; SEXUAL INTERCOURSE; SMOOTH MUSCLE RELAXATION; THORAX PAIN; TRANSLUMINAL CORONARY ANGIOPLASTY; VOMITING;

ACUTE DISEASE; ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY; ELECTROCARDIOGRAPHY; HUMANS; IMPOTENCE; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PHOSPHODIESTERASE INHIBITORS; PIPERAZINES;

EID: 21744445284     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1345/aph.1E665     Document Type: Article

References (17)

1. Ballard SA, Gingell CJ, Tang K, Turner LA, Price ME, Naylor AM. Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes. J Urol 1998;159:2164-71.
2. Boolell M, Allen MJ, Ballard SA, Gepi-Attee S, Muirhead GJ, Naylor AM, et al. Sildenafil: an orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction. Int J Impot Res 1996;8:47-52.
3. Donahue SP, Taylor RJ. Pupil-sparing third nerve palsy associated with sildenafil citrate (Viagra). Am J Ophthalmol 1998;126:476-7.
4. Morales C, Gingell C, Collins M, Wicker PA, Osterloh IH. Clinical safety of oral sildenafil citrate (Viagra) in the treatment of erectile dysfunction. Int J Impot Res 1998;10:69-74.
5. Feldman HA, Goldstein I, Hatzichristou DG, Krane RJ, McKinlay JB. Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. J Urol 1994;151:54-61.
6. Feenstra J, van Drie-Pierik RJ, Lacle CF, Snicker BH. Acute myocardial infarction associated with sildenafil. Lancet 1998;352:957-8.
7. Dakik HA, Al-Sayyed A, Sawaya JI. Viagra, sexual intercourse and acute myocardial infarction (letter). Cardiology 1999;92:220.
8. Porter A, Mager A, Birnbaum Y, Strasberg B, Sclarovsky S, Rechavia E. Acute myocardial infarction following sildenafil citrate (Viagra) intake in a nitrate-free patient. Clin Cardiol 1999;22:762-3.
9. Iglesias ML, Jerico C, Skaf E, Pedro-Botet J. Sildenafil and coronary artery disease (letter). BJU Int 2003;92:824-5.
10. Dumestre-Toulet V, Cirimele V, Gromb S, Belooussoff T, Lavault D, Ludes B, et al. Last performance with VIAGRA: post-mortem identification of sildenafil and its metabolites in biological specimens including hair sample. Forensic Sci Int 2002;126:71-6.
11. Arora RR, Timoney M, Melilli L. Acute myocardial infarction after the use of sildenafil (letter). N Engl J Med 1999;341:700.
12. Eid JF. Sildenafil citrate: current clinical experience. Int J Impot Res 2000;12(suppl 4):S62-6.
13. Webb DJ, Muirhead GJ, Wulf M, Sutton JA, Levi R, Dinsmore WW. Sildenafil citrate potentiates the hypotensive effects of nitric oxide donor drugs in male patients with stable angina. J Am Coll Cardiol 2000; 36:25-31.
14. Arruda-Olson AM, Mahoney DW, Nehra A, Leckel M, Pellikka PA. Cardiovascular effects of sildenafil during exercise in men with known or probable coronary artery disease: a randomized crossover trial. JAMA 2002;287:719-25.
15. Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981;30:239-45.
16. Kloner RA, Brown M, Prisant LM, Collins M. Effect of sildenafil in patients with erectile dysfunction taking antihypertensive therapy. Sildenafil Study Group. Am J Hypertens 2001;14:70-3.
17. Kloner RA. Hypertension as a risk for erectile dysfunction: implications for sildenafil use. J Clin Hypertens 2000;2:33-6.