Intrahepatic cytokine profile in renal-transplant patients infected by hepatitis C virus

Journal of Medical Virology

Volumn 76, Issue 4, 2005, Pages 482-488

  Kamar, Nassim ^a,b   Rostaing, Lionel ^a   Sandres Saune, Karine ^b   Selves, Janick ^b   Barthe, Carole ^b   Dubois, Martine ^b   Alric, Laurent ^b   Durand, Dominique ^a   Izopet, Jacques ^a  

^a CHU RANGUEIL   (France)

^b CHU PURPAN   (France)

Author keywords

Hepatitis C virus; Intrahepatic cytokine; Liver fibrosis; Renal transplantation; T helper 1

Indexed keywords

AZATHIOPRINE; BETA ACTIN; CYCLOSPORIN A; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 8; MESSENGER RNA; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; STEROID; TACROLIMUS; TRANSFORMING GROWTH FACTOR BETA; VIRUS RNA;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; DISEASE ACTIVITY; GENOTYPE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN TISSUE; IMMUNOPATHOGENESIS; KIDNEY GRAFT; LIVER; LIVER BIOPSY; LIVER FIBROSIS; LIVER INJURY; REAL TIME POLYMERASE CHAIN REACTION; TH1 CELL; VIRUS GENE;

ADULT; AGED; CYTOKINES; FEMALE; HEPACIVIRUS; HEPATITIS C; HUMANS; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-8; KIDNEY TRANSPLANTATION; LIVER; LIVER CIRRHOSIS; MALE; MIDDLE AGED; RNA, MESSENGER; RNA, VIRAL; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA;

HEPATITIS C VIRUS;

EID: 21744438958     PISSN: 01466615     EISSN: None     Source Type: Journal    
DOI: 10.1002/jmv.20387     Document Type: Article

References (29)

1. Alric L, Di-Martino V, Selves J, Cacoub P, Charlotte F, Reynaud D, Piette JC, Peron JM, Vinel JP, Durand D, Izopet J, Poynard T, Duffaut M, Rostaing L. 2002. Long-term impact of renal transplantation on liver fibrosis during hepatitis C virus infection. Gastroenterology 123:1494-1499.
2. Bedossa P, Poynard T. 1996. An algorithm for the grading of activity in chronic hepatitis C. The METAVIR Cooperative Study Group. Hepatology 24:289-293.
3. Bertoletti A, D'Elios MM, Boni C, De Carli M, Zignego AL, Durazzo M, Missale G, Penna A, Fiaccadori F, Del Prete G, Ferrari C. 1997. Different cytokine profiles of intraphepatic T cells in chronic hepatitis B and hepatitis C virus infections. Gastroenterology 112:193-199.
4. Chisari FV. 1997. Cytotoxic T cells and viral hepatitis. J Clin Invest 99:1472-1477.
5. Conti F, Calmus Y, Rouer E, Gaulard P, Louvel A, Houssin D, Zafrani ES. 1999. Increased expression of interleukin-4 during liver allograft rejection. J Hepatol 30:935-943.
6. Fehr T, Riehl HM, Nigg L, Grüte E, Ammann P, Renner EL, Ambühl PM. 2003. Evaluation of hepatitis B and hepatitis C virus-infected renal allograft recipients with liver biopsy and noninvasive parameters. Am J Kidney Dis 42:193-201.
7. Fukuda R, Ishimura N, Ishihara S, Chowdhury A, Morlyama N, Nogami C, Miyake T, Niigaki M, Tokuda A, Satoh S, Sakai S, Akagi S, Watanabe M, Fukumoto S. 1996. Intrahepatic expression of proinflammatory cytokine mRNAs and interferon efficacy in chronic hepatitis C. Liver 16:390-399.
8. Hill DB, Marsano LS, McClain CJ. 1993. Increased plasma interleukin-8 concentrations in alcoholic hepatitis. Hepatology 18:576-580.
9. Hiroishi K, Kita H, Kojima M, Okamoto H, Moriyama T, Kaneko T, Ishikawa T, Ohnishi S, Aikawa T, Tanaka N, Yazaki Y, Mitamura K, Imawari M. 1997. Cytotoxic T lymphocyte response and viral load in hepatitis C virus infection. Hepatology 25:705-712.
10. Kamar N, Rostaing L, Selves J, Sandres-Sauné K, Alric L, Durand D, Izopet J. Natural history of hepatitis C virus-related liver fibrosis after renal transplantation. Am J Transplant (in press)
11. Kaplanski G, Farnarier C, Payan MJ, Bongrand P, Durand JM. 1997. Increased levels of soluble adhesion molecules in the serum of patients with hepatitis C. Correlation with cytokine concentrations and liver inflammation and fibrosis. Dig Dis Sci 42:2277-2284.
12. Kita H, Moriyama T, Kaneko T, Harase I, Nomura M, Miura H, Nakamura I, Yazaki Y, Imawari M. 1993. HLA B44-restricted cytotoxic T lymphocytes recognizing an epitope on hepatitis C virus nucleocapsid protein. Hepatology 18:1039-1044.
13. Koziel MJ, Dudley D, Wong JT, Dienstag J, Houghton M, Ralston R, Walker BD. 1992. Intrahepatic cytotoxic T lymphocytes specific for hepatitis C virus in persons with chronic hepatitis. J Immunol 149:3339-3344.
14. Koziel MJ, Dudley D, Afdhal N, Choo QL, Houghton M, Ralston R, Walker BD. 1993. Hepatitis C virus (HCV)-specific cytotoxic T lymphocytes recognize Epitopes in the core and envelope proteins of HCV. J Virol 67:7522-7532.
15. Legendre C, Garrigue V, Le Bihan C, Mamzer-Bruneel MF, Chaix ML, Landais P, Kreis H, Pol S. 1998. Harmful long-term impact of hepatitis C virus infection in kidney transplant recipients. Transplantation 65:667-670.
16. Li CP, Lee FY, Tsai YT, Lin HC, Lu RH, Hou MC, Wang TF, Chen LS, Wang SS, Lee SD. 1996. Plasma interleukin-8 levels in patients with post-hepatitic cirrhosis: Relationship to severity of liver disease, portal hypertension and hyperdynamic circulation. J Gastroenterol Hepatol 11:635-640.
17. Liaw YF, Lee CS, Tsai SL, Liaw BW, Chen TC, Sheen IS, Chu CM. 1995. T-cell-mediated autologous hepatocytotoxicity in patients with chronic hepatitis C virus infection. Hepatology 22:1368-1373.
18. Mahmood S, Sho M, Yasuhara Y, Kawanaka M, Niiyama G, Togawa K, Ito T, Takahashi N, Kinoshita M, Yamada G. 2002. Clinical significance of intrahepatic interleukin-8 in chronic hepatitis C patients. Hepatol Res 24:413-419.
19. Napoli J, Bishop GA, McCaughan GW. 1994. Increased intrahepatic messenger RNA expression of interleukins 2, 6, and 8 in human cirrhosis. Gastroenterology 107:789-798.
20. Napoli J, Bishop GA, McGuinness PH, Painter DM, McCaughan GW. 1996. Progressive liver injury in chronic hepatitis C infection correlates with increased intrahepatic expression of Th1-associated cytokines. Hepatology 24:759-765.
21. Nelson DR, Gonzalez-Peralta RP, Qian K, Xu Y, Marousis CG, Davis GL, Lau JY. 1997. Transforming growth factor-beta 1 in chronic hepatitis C. J Viral Hepat 4:29-35.
22. Ray S, Broor SL, Vaishnav Y, Sarkar C, Girish R, Dar L, Seth P, Broor S. 2003. Transforming growth factor beta in hepatitis C virus infection: In vivo and in vitro findings. J Gastroenterol Hepatol 18:393-403.
23. Roth D, Reddy KR, Kupin W, Burke G, Ciancio G, Garces G, Colona J, Petrin D, Miller J. 2004. Long-term impact of HCV on clinical outcomes and liver histology in kidney recipients. Am J Transplant A 478:289.
24. Roulot D, Durand H, Coste T, Rautureau J, Strosberg AD, Benarous R, Marullo S. 1995. Quantitative analysis of transforming growth factor beta 1 messenger RNA in the liver of patients with chronic hepatitis C: Absence of correlation between high levels and severity of disease. Hepatology 21:298-304.
25. Schirren CA, Jung M, Worzfeld T, Mamin M, Baretton GB, Gruener NH, Gerlach JT, Diepolder HM, Zachoval R, Pape GR. 2000. Cytokine profile of liver- and blood-derived nonspecific T cells after liver transplantation: T helper cells type 1/0 lymphokines dominate in recurrent hepatitis C virus infection and rejection. Liver Transpl 6:222-228.
26. Schroder JM. 1989. The monocyte-derived neutrophil activating peptide (NAP/interleukin 8) stimulates human neutrophil arachidonate-5-lipoxygenase, but not the release of cellular arachidonate. J Exp Med 170:847-863.
27. Shimoda K, Begum NA, Shibuta K, Mori M, Bonkovsky HL, Banner BF, Barnard GF. 1998. Interleukin-8 and hIRH (SDF1-alpha/PBSF) mRNA expression and histological activity index in patients with chronic hepatitis C. Hepatology 28:108-115.
28. Taniguchi H, Kato N, Otsuka M, Goto T, Yoshida H, Shiratori Y, Omata M. 2004. Hepatitis C virus core protein upregulates transforming growth factor-beta 1 transcription. J Med Virol 72: 52-59.
29. Zekry A, Bishop GA, Bowen DG, Gleeson MM, Guney S, Painter DM, McCaughan GW. 2002. Intrahepatic cytokine profiles associated with posttransplantation hepatitis C virus-related liver injury. Liver Transpl 8:292-301.