Structural determinants of factor IX(a) binding in nitrophorin 2, a lipocalin inhibitor of the intrinsic coagulation pathway

Journal of Biological Chemistry

Volumn 280, Issue 26, 2005, Pages 25022-25028

  Gudderra, Nanda P ^a   Ribeiro, José M C ^a   Andersen, John F ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; CALORIMETRY; COAGULATION; ENZYME INHIBITION; SURFACE PLASMON RESONANCE; TITRATION;

ISOTHERMAL TITRATION CALORIMETRY; NITROPHORIN; POTENT INHIBITION; XASE SYSTEM;

NITROGEN COMPOUNDS;

BLOOD CLOTTING FACTOR 9; BLOOD CLOTTING FACTOR 9A; HEME; HISTAMINE; INTRINSIC FACTOR; INTRINSIC FACTOR XASE COMPLEX; LIPOCALIN; MUTANT PROTEIN; NITROPHORIN 2; NITROPHORIN 3; UNCLASSIFIED DRUG; VALINE;

ARTICLE; BETA SHEET; BINDING AFFINITY; BLOOD CLOTTING; COMPLEX FORMATION; GENE MUTATION; INSECT; ISOTHERMAL TITRATION CALORIMETRY; POINT MUTATION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SURFACE PLASMON RESONANCE;

AMINO ACID SEQUENCE; ANIMALS; CALORIMETRY; CARRIER PROTEINS; CELL MEMBRANE; DOSE-RESPONSE RELATIONSHIP, DRUG; FACTOR IX; FACTOR IXA; HEME; HEMEPROTEINS; HISTAMINE; HUMANS; INHIBITORY CONCENTRATION 50; KINETICS; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; POINT MUTATION; PROTEIN BINDING; RHODNIUS; SALIVARY PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SURFACE PLASMON RESONANCE; TIME FACTORS;

INSECTA; RHODNIUS PROLIXUS;

EID: 21644474357     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M504386200     Document Type: Article

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