Design and evaluation of an emulsion vehicle for paclitaxel. I. Physicochemical properties and plasma stability

Pharmaceutical Research

Volumn 21, Issue 9, 2004, Pages 1573-1580

  Han, Jihong ^a   Davis, Stanley S ^a   Papandreou, Catherine ^b   Melia, Colin D ^a   Washington, Clive ^a,c  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY   (Greece)

^c ASTRAZENECA   (United Kingdom)

Author keywords

Block copolymer; Emulsion; Paclitaxel; Pegylated phospholipids; Steric stabilization

Indexed keywords

1,2 DIPALMITOYLTIN GLYCERO 3 PHOSPHOETHANOLAMINE N [POLY(ETHYLENE GLYCOL) 5000]; DEOXYCHOLATE SODIUM; DRUG VEHICLE; EMULSIFYING AGENT; MACROGOL; PACLITAXEL; PHOSPHATIDYLCHOLINE; SODIUM; STABILIZING AGENT; UNCLASSIFIED DRUG; ALPHA TOCOPHEROL; ANTINEOPLASTIC AGENT; BILE ACID; MACROGOL DERIVATIVE; POLOXAMER;

ARTICLE; CRYSTAL STRUCTURE; CRYSTALLIZATION; DRUG MIXTURE; DRUG SCREENING; EMULSION; FLUIDIZATION; LIGHT SCATTERING; MICROFLUIDICS; MICROSCOPY; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; ANIMAL; BLOOD; CHEMISTRY; DRUG STABILITY; EVALUATION; VEHICLES;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BILE ACIDS AND SALTS; DRUG STABILITY; EMULSIFYING AGENTS; EMULSIONS; MICROFLUIDICS; PACLITAXEL; POLOXAMER; POLYETHYLENE GLYCOLS; VEHICLES; VITAMIN E;

EID: 21644435623     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:PHAM.0000041451.70367.21     Document Type: Article

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