Adherence to and invasion of human brain microvascular endothelial cells are promoted by fibrinogen-binding protein FbsA of Streptococcus agalactiae

Infection and Immunity

Volumn 73, Issue 7, 2005, Pages 4404-4409

  Tenenbaum, Tobias ^a   Bloier, Christiane ^a   Adam, Rüdiger ^a   Reinscheid, Dieter J ^b   Schroten, Horst ^a,c  

^a UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

^b UNIVERSITY OF ULM   (Germany)

^c HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; BINDING PROTEIN; EPITOPE; FIBRINOGEN; FIBRINOGEN BINDING PROTEIN; HYBRID PROTEIN; INTERLEUKIN 8; MONOCLONAL ANTIBODY; PROTEIN FBSA; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GENE; BACTERIAL MENINGITIS; BACTERIUM ADHERENCE; BRAIN; CELL INVASION; CONTROLLED STUDY; CYTOKINE RELEASE; ENDOTHELIUM CELL; FBSA GENE; GENE EXPRESSION; HOST CELL; HUMAN; HUMAN CELL; LACTOCOCCUS LACTIS; NEWBORN SEPSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; STREPTOCOCCUS AGALACTIAE; WILD TYPE;

BACTERIAL ADHESION; BACTERIAL PROTEINS; BLOOD-BRAIN BARRIER; BRAIN; CARRIER PROTEINS; ENDOTHELIAL CELLS; HUMANS; INTERLEUKIN-8; STREPTOCOCCUS AGALACTIAE;

EID: 21544480286     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.73.7.4404-4409.2005     Document Type: Article

References (36)

1. Badger, J. L., M. F. Stins, and K. S. Kim. 1999. Citrobacter freundii invades and replicates in human brain microvascular endothelial cells. Infect. Immun. 67:4208-4215.
2. Baker, C. J., and M. S. Edwards. 1995. Group B streptococcal infections, p. 980-1054. In J. S. Remington and J. O. Klein (ed.), Infectious disease of the fetus and newborn infant. The W. B. Saunders Co., Philadelphia, Pa.
3. Beckmann, C., J. D. Waggoner, T. O. Harris, G. S. Tamura, and C. E. Rubens. 2002. Identification of novel adhesins from group B streptococci by use of phage display reveals that C5a peptidase mediates fibronectin binding. Infect. Immun. 70:2869-2876.
4. Butler, K. M., C. J. Baker, and M. S. Edwards. 1987. Interaction of soluble fibronectin with group B streptococci. Infect. Immun. 55:2404-2408.
5. Cheng, Q., D. Stafslien, S. S. Purushothaman, and P. Cleary. 2002. The group B streptococcal C5a peptidase is both a specific protease and an invasin. Infect. Immun. 70:2408-2413.
6. Courtney, H. S., Y. Li, J. B. Dale, and D. L. Hasty. 1994. Cloning, sequencing, and expression of a fibronectin/fibrinogen-binding protein from group A streptococci. Infect. Immun. 62:3937-3946.
7. Doran, K. S., J. C. Chang, V. M. Benoit, L. Eckmann, and V. Nizet. 2002. Group B streptococcal β-hemolysin/cytolysin promotes invasion of human lung epithelial cells and the release of interleukin-8. J. Infect. Dis. 185:196-203.
8. Doran, K. S., G. Y. Liu, and V. Nizet. 2003. Group B streptococcal β-hemolysin/cytolysin activates neutrophil signaling pathways in brain endothelium and contributes to development of meningitis. J. Clin. Investig. 112:736-744.
9. Eckmann, L., H. C. Jung, C. Schurer-Maly, A. Panja, E. Morzycka-Wroblewska, and M. F. Kagnoff. 1993. Differential cytokine expression by human intestinal epithelial cell lines: regulated expression of interleukin 8. Gastroenterology 105:1689-1697.
10. Elsinghorst, E. A. 1994. Measurement of invasion by gentamycin resistance, p. 405-419. In J. N. Abelson and M. I. Simon (ed.), Bacterial pathogenesis, part B. Academic Press, New York, N.Y.
11. Ferrieri, P., B. Burke, and J. Nelson. 1980. Production of bacteremia and meningitis in infant rats with group B streptococcal serotypes. Infect. Immun. 27:1023-1032.
12. Greiffenberg, L., W. Goebel, K. S. Kim, I. Weiglein, A. Bubert, F. Engelbrecht, M. Stins, and M. Kuhn. 1998. Interaction of Listeria monocytogenes with human brain microvascular endothelial cells: InlB-dependent invasion, long-term intracellular growth, and spread from macrophages to endothelial cells. Infect. Immun. 66:5260-5267.
13. Gutekunst, H., B. J. Eikmanns, and D. J. Reinscheid. 2003. Analysis of RogB-controlled virulence mechanisms and gene expression in Streptococcus agalactiae. Infect. Immun. 71:5056-5064.
14. Gutekunst, H., B. J. Eikmanns, and D. J. Reinscheid. 2004. The novel fibrinogen-binding protein FbsB promotes Streptococcus agalactiae invasion into epithelial cells. Infect. Immun. 72:3495-3504.
15. Kotarsky, H., A. Thern, G. Lindahl, and U. Sjöbring. 2000. Strain-specific restriction of the antiphagocytic property of group A streptococcal M proteins. Infect. Immun. 68:107-112.
16. McDevitt, D., P. Francois, P. Vaudaux, and T. J. Foster. 1994. Molecular characterization of the clumping factor (fibrinogen receptor) of Staphylococcus aureus. Mol. Microbiol. 11:237-248.
17. Ni Eidhin, D., S. Perkins, P. Francois, P. Vaudaux, M. Höök, and T. J. Foster. 1998. Clumping factor B (ClfB), a new surface-located fibrinogen-binding adhesin of Staphylococcus aureus. Mol. Microbiol. 30:245-257.
18. Nizet, V., R. L. Gibson, E. Y. Chi, P. E. Framson, M. Hulse, and C. E. Rubens. 1996. Group B streptococcal beta-hemolysin expression is associated with injury of lung epithelial cells. Infect. Immun. 64:3818-3826.
19. Nizet, V., K. S. Kim, M. Stins, M. Jonas, E. Y. Chi, D. Nguyen, and C. E. Rubens. 1997. Invasion of brain microvascular endothelial cells by group B streptococci. Infect. Immun. 65:5074-5081.
20. Pietrocola, G., A. Schubert, L. Visai, M. Torti, J. R. Fitzgerald, T. J. Foster, D. J. Reinscheid, and P. SpeziaIe. 2005. FbsA, a fibrinogen-binding protein from Streptococcus agalactiae, mediates platelet aggregation. Blood 105: 1052-1059.
21. Prasadarao, N. V., C. A. Wass, J. N. Weiser, M. F. Stins, S.-H. Huang, and K. S. Kim. 1996. Outer membrane protein A of Escherichia coli contributes to invasion of brain microvascular endothelial cells. Infect. Immun. 64:146-153.
22. Rubens, C. E., S. Smith, M. Hulse, E. Y. Chi, and G. van Belle. 1992. Respiratory epithelial cell invasion by group B streptococci. Infect. Immun. 60:5157-5163.
23. Samen, U., B. Gottschalk, B. J. Eikmanns, and D. J. Reinscheid. 2004. Relevance of peptide uptake systems to the physiology and virulence of Streptococcus agalactiae. J. Bacteriol. 186:1398-1408.
24. 2-microglobulin detected in strains of group B streptococci. Infect. Immun. 31:856-861.
25. Schroten, H., B. Spors, C. Hucke, M. Stins, K. S. Kim, R. Adam, and W. Daubener. 2001. Potential role of human brain microvascular endothelial cells in the pathogenesis of brain abscess: inhibition of Staphylococcus aureus by activation of indoleamine 2,3-dioxygenase. Neuropediatrics 32:206-210.
26. Schubert, A., K. Zakikhany, M. Schreiner, R. Frank, B. Spellerberg, B. J. Eikmanns, and D. J. Reinscheid. 2002. A fibrinogen receptor from group B Streptococcus interacts with fibrinogen by repetitive units with novel ligand binding sites. Mol. Microbiol. 46:557-569.
27. Schubert, A., K. Zakikhany, G. Pietrocola, A. Meinke, P. Speziale, B. J. Eikmanns, and D. J. Reinscheid. 2004. The fibrinogen receptor FbsA promotes adherence of Streptococcus agalactiae to human epithelial cells. Infect. Immun. 72:6197-6205.
28. Spellerberg, B., E. Rozdzinski, S. Martin, J. Weber-Heynemann, N. Schnitzler, R. Lütticken, and A. Podbielski. 1999. Lmb, a protein with similarities to the LraI adhesin family, mediates attachment of Streptococcus agalactiae to human laminin. Infect. Immun. 67:871-878.
29. Stins, M., F. Gilles, and K. S. Kim. 1997. Selective expression of adhesion molecules on human brain microvascular endothelial cells. J. Neuroimmunol. 76:81-90.
30. Stins, M. F., N. V. Prasadarao, J. Zhou, M. Arditi, and K. S. Kim. 1997. Bovine brain microvascular endothelial cells transfected with SV40-large T antigen: development of an immortalized cell line to study pathophysiology of CNS disease. In Vitro Cell. Dev. Biol. Anim. 33:243-247.
31. Stins, M. F., J. Badger, and K. Sik Kim. 2001. Bacterial invasion and transcytosis in transfected human brain microvascular endothelial cells. Microb. Pathog. 30:19-28.
32. Tamura, G. S., and C. E. Rubens. 1995. Group B streptococci adhere to a variant of fibronectin attached to a solid phase. Mol. Microbiol. 15:581-589.
33. Thern, A., M. Wastfelt, and G. Lindahl. 1998. Expression of two different antiphagocytic M proteins by Streptococcus pyogenes of the OF+ lineage. J. Immunol. 160:860-869.
34. Valenti-Weigand, P., P. Benkel, M. Rohde, and G. S. Chhatwal. 1996. Entry and intracellular survival of group B streptococci in J774 macrophages. Infect. Immun. 64:2467-2473.
35. Waite, D. C., E. J. Alper, and B. J. Mady. 1996. Adult group B streptococcal disease. Ann. Intern. Med. 125:152-153.
36. Zysk, G., B. K. Schneider-Wald, J. H. Hwang, L. Bejo, K. S. Kim, T. J. Mitchell, R. Hakenbeck, and H.-P. Heinz. 2001. Pneumolysin is the main inducer of cytotoxicity to brain microvascular endothelial cells caused by Streptococcus pneumoniae. Infect. Immun. 69:845-852.