Nω-hydroxy-L-arginine homologues and hydroxylamine as nitric oxide-dependent vasorelaxant agents

European Journal of Pharmacology

Volumn 516, Issue 3, 2005, Pages 260-267

  Beranova, Petra ^a   Chalupsky, Karel ^a   Kleschyov, Andrei L ^b   Schott, Christa ^a   Boucher, Jean Luc ^a   Mansuy, Daniel ^a   Munzel, Thomas ^b   Muller, Bernard ^a   Stoclet, Jean Claude ^a,c  

^a CNRS   (France)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

^c UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Electron paramagnetic resonance; Hydroxylamine; N hydroxy L arginine homologue; Nitric oxide release; Vasorelaxation

Indexed keywords

12 (N OMEGA HYDROXYARGININE); 1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 2 PHENYL 4,4,5,5 TETRAMETHYLIMIDAZOLINE 1 OXYL 3 OXIDE; 4 (DINOR N OMEGA HYDROXYARGININE); 8 (NOR N OMEGA HYDROXYARGININE); 8 BROMO CYCLIC GMP; 9 (HOMO N OMEGA HYDROXYARGININE); ALPHA AMINO ACID; ARGININE DERIVATIVE; CYTOCHROME P450 INHIBITOR; ETHOXYRESORUFIN; GUANIDINE DERIVATIVE; GUANYLATE CYCLASE; GUANYLATE CYCLASE INHIBITOR; HYDROXYLAMINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SCAVENGER; UNCLASSIFIED DRUG; 1H (1,2,4)OXADIAZOLO(4,3 A)QUINOXALIN 1 ONE; 1H-(1,2,4)OXADIAZOLO(4,3-A)QUINOXALIN-1-ONE; 2-PHENYL-4,4,5,5-TETRAMETHYLIMIDAZOLINE-1-OXYL-3-OXIDE; AMINE OXIDE; ARGININE; CYCLIC GMP; DRUG DERIVATIVE; ENZYME INHIBITOR; IMIDAZOLE DERIVATIVE; N(OMEGA) HYDROXYARGININE; N(OMEGA)-HYDROXYARGININE; OXADIAZOLE DERIVATIVE; QUINOXALINE DERIVATIVE; VASODILATOR AGENT;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; ELECTRON SPIN RESONANCE; ENDOTHELIUM; ENZYME ACTIVATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SEQUENCE HOMOLOGY; VASODILATATION; ANIMAL; CHEMISTRY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; IN VITRO STUDY; PHYSIOLOGY; SIGNAL TRANSDUCTION; THORACIC AORTA; VASCULAR ENDOTHELIUM; WISTAR RAT;

ANIMALS; AORTA, THORACIC; ARGININE; CYCLIC GMP; CYCLIC N-OXIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRON SPIN RESONANCE SPECTROSCOPY; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; GUANYLATE CYCLASE; HYDROXYLAMINE; IMIDAZOLES; MALE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXADIAZOLES; QUINOXALINES; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; VASODILATION; VASODILATOR AGENTS;

EID: 21544438206     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.04.021     Document Type: Article

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