Lack of proinflammatory effects of free fatty acids on human umbilical cord vein endothelial cells and leukocytes

Acta Obstetricia et Gynecologica Scandinavica

Volumn 84, Issue 7, 2005, Pages 672-678

  Holthe, Mette Ree ^a   Andersson, Yvonne ^b   Lyberg, Torstein ^a  

^a ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

Adhesion molecules; CD11b; CD62L; E selectin; Endothelial cells; Free fatty acids; ICAM 1; Leukocytes; Preeclampsia; Reactive oxygen species; VCAM 1

Indexed keywords

CD11B ANTIGEN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; FATTY ACID; HYDROGEN PEROXIDE; INTERCELLULAR ADHESION MOLECULE 1; L SELECTIN; LINOLEIC ACID; LIPOPOLYSACCHARIDE; MESSENGER RNA; OLEIC ACID; PALMITIC ACID; REACTIVE OXYGEN METABOLITE; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; CELL CULTURE; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; LEUKOCYTE ACTIVATION; NUCLEOTIDE SEQUENCE; PREECLAMPSIA; PREGNANCY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UMBILICAL VEIN;

ANALYSIS OF VARIANCE; CELLS, CULTURED; E-SELECTIN; ENDOTHELIAL CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FATTY ACIDS, NONESTERIFIED; FEMALE; FLOW CYTOMETRY; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; LEUKOCYTES; PRE-ECLAMPSIA; PREGNANCY; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; UMBILICAL VEINS; VASCULAR CELL ADHESION MOLECULE-1;

EID: 21444461565     PISSN: 00016349     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0001-6349.2005.00799.x     Document Type: Article

References (33)

1. Roberts JM, Taylor RN, Musci TJ, Rodgers GM, Hubel CA, McLaughlin MK. Preeclampsia: an endothelial cell disorder. Am J Obstet Gynecol 1989; 161: 1200-4.
2. Lim KH, Zhou Y, Janatpour M, McMaster M, Bass K, Chun SH et al. Human cytotrophoblast differentiation/invasion is abnormal in pre-eclampsia. Am J Pathol 1997; 151: 1809-18.
3. Redman CW, Sacks GP, Sargent IL. Preeclampsia: an excessive maternal inflammatory response to pregnancy. Am J Obstet Gynecol 1999; 180: 499-506.
4. McEver RP. Adhesive interactions of leukocytes, platelets, and the vessel wall during hemostasis and inflammation. Thromb Haemost 2001; 86: 746-56.
5. Krauss T, Kuhn W, Lakoma C, Augustin HG. Circulating endothelial cell adhesion molecules as diagnostic markers for the early identification of pregnant women at risk for development of preeclampsia. Am J Obstet Gynecol 1997; 177: 443-9.
6. Lorentzen B, Endresen MJ, Clausen T, Henriksen T. Fasting srum free fatty acids and triglycerides are increased before 20 weeks of gestation in women who later develope preeclampsia. Hypertens Pregnancy 1994; 13: 103-9.
7. Lorentzen B, Henriksen T. Plasma lipids and vascular dysfunction in preeclampsia. Semin Reprod Endocrinol 1998; 16: 33-9.
8. Lorentzen B, Endresen MJ, Hovig T, Haug E, Henriksen T. Sera from preeclamptic women increase the content of triglycerides and reduce the release of prostacyclin in cultured endothelial cells. Thromb Res 1991; 63: 363-72.
9. Endresen MJ, Morris JM, Nobrega AC, Buckley D, Linton EA, Redman CW. Serum from preeclamptic women induces vascular cell adhesion molecule-1 expression on human endothelial cells in vitro: a possible role of increased circulating levels of free fatty acids. Am J Obstet Gynecol 1998; 179: 665-70.
10. Steinberg HO, Tarshoby M, Monestel R, Hook G, Cronin J, Johnson A et al. Elevated circulating free fatty acid levels impair endothelium-dependent vasodilation. J Clin Invest 1997; 100: 1230-9.
11. Jaffe EA, Nachman RL, Becker CG, Minick CR. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J Clin Invest 1973; 52: 2745-56.
12. Endresen MJ, Tosti E, Heimli H, Lorentzen B, Henriksen T. Effects of free fatty acids found increased in women who develop pre-eclampsia on the ability of endothelial cells to produce prostacyclin, cGMP and inhibit platelet aggregation. Scand J Clin Lab Invest 1994; 54: 549-57.
13. Haraldsen G, Kvale D, Lien B, Farstad IN, Brandtzaeg P. Cytokine-regulated expression of E-selectin, intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1) in human microvascular endothelial cells. J Immunol 1996; 156: 2558-65.
14. McLean IW, Nakane PK. Periodate-lysine-paraformaldehyde fixative. A new fixation for immunoelectron microscopy. J Histochem Cytochem 1974; 22: 1077-83.
15. Holthe MR, Staff AC, Berge LN, Lyberg T. Leukocyte adhesion molecules and reactive oxygen species in preeclampsia. Obstet Gynecol 2004; 103: 913-22.
16. Saetre T, Kahler H, Foster SJ, Lyberg T. Peptidoglycan and lipoteichoic acid, components of the streptococcal cell wall, have marked and differential effects on adhesion molecule expression and the production of reactive oxygen species in human whole blood leukocytes. Scand J Clin Lab Invest 2000; 60(4): 311-21.
17. Altman DG. Practical Statistics for Medical Research (Chapter 8). London: Chapman & Hall, 1999.
18. Reissig D, Rassoul F, Salvetter J, Wagner O, Richter V. Effect of fatty acids on expression of endothelial leukocyte adhesion molecules. Eur J Nutr 2003; 42: 224-7.
19. Carluccio MA, Massaro M, Bonfrate C, Siculella L, Maffia M, Nicolardi G et al. Oleic acid inhibits endothelial activation: a direct vascular antiatherogenic mechanism of a nutritional component in the mediterranean diet. Arterioscler Thromb Vasc Biol 1999; 19: 220-8.
20. De Wolf F, Robertson WB, Brosens I. The ultrastructure of acute atherosis in hypertensive pregnancy. Am J Obstet Gynecol 1975; 123: 164-74.
21. Khong TY, Mott C. Immunohistologic demonstration of endothelial disruption in acute atherosis in pre-eclampsia. Eur J Obstet Gynecol Reprod Biol 1993; 51: 193-7.
22. Budak E, Madazli R, Aksu MF, Benian A, Gezer A, Palit N et al. Vascular cell adhesion molecule-1 (VCAM-1) and leukocyte activation in pre-eclampsia and eclampsia. Int J Gynecol Obstet 1998; 63: 115-21.
23. Austgulen R, Lien E, Vince G, Redman CW. Increased maternal plasma levels of soluble adhesion molecules (ICAM-1, VCAM-1, E-selectin) in preeclampsia. Eur J Obstet Gynecol Reprod Biol 1997; 71: 53-8.
24. Heyl W, Handt S, Reister F, Gehlen J, Mittermayer C, Rath W. The role of soluble adhesion molecules in evaluating endothelial cell activation in preeclampsia. Am J Obstet Gynecol 1999; 180: 68-72.
25. Hwang SJ, Ballantyne CM, Sharrett AR, Smith LC, Davis CE, Gotto AMJ et al. Circulating adhesion molecules VCAM-1, ICAM-1, and E-selectin in carotid atherosclerosis and incident coronary heart disease cases: the Atherosclerosis Risk In Communities (ARIC) study. Circulation 1997; 96: 4219-25.
26. Leeuwenberg JF, Smeets EF, Neefjes JJ, Shaffer MA, Cinek T, Jeunhomme TM et al. E-selectin and intercellular adhesion molecule-1 are released by activated human endothelial cells in vitro. Immunology 1992; 77: 543-9.
27. Hooper NM, Karran EH, Turner AJ. Membrane protein secretases. Biochem J 1997; 321: 265-79.
28. Garton KJ, Gough PJ, Philalay J, Wille PT, Blobel CP, Whitehead RH et al. Stimulated shedding of vascular cell adhesion molecule 1 (VCAM-1) is mediated by tumor necrosis factor-alpha-converting enzyme (ADAM 17). J Biol Chem 2003; 278: 37459-64.
29. Sacks GP, Studena K, Sargent K, Redman CW. Normal pregnancy and preeclampsia both produce inflammatory changes in peripheral blood leukocytes akin to those of sepsis [see comments]. Am J Obstet Gynecol 1998; 179: 80-6.
30. von Dadelszen P, Wilkins T, Redman CW. Maternal peripheral blood leukocytes in normal and pre-eclamptic pregnancies. Br J Obstet Gynaecol 1999; 106: 576-81.
31. Haeger M, Unander M, Norder-Hansson B, Tylman M, Bengtsson A. Complement, neutrophil, and macrophage activation in women with severe preeclampsia and the syndrome of hernolysis, elevated liver enzymes, and low platelet count. Obstet Gynecol 1992; 79: 19-26.
32. Akamatsu H, Komura J, Miyachi Y, Asada Y, Niwa Y. Suppressive effects of linoleic acid on neutrophil oxygen metabolism and phagocytosis. J Invest Dermatol 1990; 95: 271-4.
33. Sampson MJ, Davies IR, Brown JC, Morgan V, Richardson T. James AJ et al. n-3 polyunsaturated fatty acid supplementation, monocyte adhesion molecule expression and pro-inflammatory mediators in Type 2 diabetes mellitus. Diabet Med 2001; 18: 51-8.