Immunostaining of stage-specific embryonic antigen-4 in intratubular germ cell neoplasia unclassified and in testicular germ-cell tumors

Oncology Reports

Volumn 10, Issue 5, 2003, Pages 1097-1104

  Tokuyama, Satoru ^a   Saito, Seiichi ^a   Takahashi, Toshiko ^a   Ohyama, Chikara ^b   Akihiro, I T O ^a   Kanto, Satoru ^a   Satoh, Makoto ^a   Hoshi, Senji ^a   Endoh, Mareyuki ^b   Arai, Yoichi ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b AKITA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Globo series glycolipids; Intratubular germ cell neoplasia unclassified; Spermatogonia; Stage specific embryonic antigen 4; Testicular germ cell tumor

Indexed keywords

GLYCOLIPID; GLYCOSPHINGOLIPID; STAGE SPECIFIC EMBRYO ANTIGEN 4; STAGE-SPECIFIC EMBRYONIC ANTIGEN 4;

ADULT; ARTICLE; BIOSYNTHESIS; BIOTINYLATION; CHEMISTRY; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; MIDDLE AGED; NEOPLASM; SEMINOMA; TESTIS TUMOR; THIN LAYER CHROMATOGRAPHY; YOLK SAC TUMOR;

ADULT; BIOTINYLATION; CHROMATOGRAPHY, THIN LAYER; ENDODERMAL SINUS TUMOR; GLYCOLIPIDS; GLYCOSPHINGOLIPIDS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NEOPLASMS, GERM CELL AND EMBRYONAL; SEMINOMA; TESTICULAR NEOPLASMS;

EID: 2142860757     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.10.5.1097     Document Type: Article

References (36)

1. Richie JP: Neoplasms of the testis. In: Campbell's Urology. Walsh PC, Retik AB, Vaughan ED Jr and Wein AJ (eds). Saunders, Philadelphia, pp2411-2452, 1998.
2. Skakkebaek NE: Possible carcinoma-in situ of the testis. Lancet 2: 516-517, 1972.
3. Dieckmann K-P and Skakkebaek NE: Carcinoma in situ of the testis: review of biological and clinical features. Int J Cancer 83: 815-822, 1999.
4. Ulbright TM and Roth LM: Testicular and paratesticular neoplasms. In: Diagnostic Surgical Pathology. Sternberg SS (ed). Raven, New York, pp1885-1947, 1994.
5. Ulbright TM, Amin MB and Young RH: Tumors of the testis, adnexia, spermatic cord and scrotum. In: Atlas of Tumor Pathology, Third Series, Fascicle 25. Armed Forces Institute of Pathology, Washington, DC, pp41-58, 1999.
6. Friedman NB: The comparative morphogenesis of extragenital and gonadal teratoid tumors. Cancer 4: 265-276, 1951.
7. Mostofi FK and Price EB: Tumors of germ-cell origin: tumors of the male genital system. In: Atlas of Tumor Pathology, Fascicle 8, Series 2. Firminger HI (ed). Armed Forces Institute of Pathology, Washington, DC, pp21-39, 1973.
8. Johnson DE, Appelt G, Samuels ML and Luna M: Metastasis from testicular carcinoma: study of 78 autopsied cases. Urology 8: 234-239, 1976.
9. Bredael JJ, Vugrin D and Whitmore WF Jr: Autopsy findings in 154 patients with germ cell tumors of the testis. Cancer 50: 548-551, 1982. (Pubitemid 12097426)
10. Srigly JR, Mackay B, Toth P and Ayala A: The ultrastructure and histogenesis of male germ cell neoplasia with emphasis on seminoma with early carcinomatous features. Ultrastruct Pathol 12: 67-86, 1988. (Pubitemid 18052788)
11. Oosterhuis JW, Castedo SMMJ, De Jong B, Cornelisse CJ, Sleijfer DTh and Koops HS: Ploidy of primary germ cell tumors of the testis: pathogenetic and clinical relevance. Lab Invest 60: 14-21, 1989. (Pubitemid 19053514)
12. De Jong B, Oosterhuis JW, Castedo SMMJ, Vos AM and Meerman GJ: Pathogenesis of adult testicular germ cell tumors: a cytogenetic model. Cancer Genet Cytogenet 48: 143-167, 1990. (Pubitemid 20310681)
13. Czaja JT and Ulbright TM: Evidence for the transformation of seminoma to yolk sac tumor, with histogenetic consideration. Am J Clin Pathol 97: 468-477, 1992.
14. Hakomori S: Tumor malignancy defined by aberrant glycosylation and sphingo (glyco) lipid metabolism. Cancer Res 56: 5309-5318, 1996.
15. Damjanov I, Fox N, Knowles BB, Solter D, Lange PH and Fraley EE: Immunohistochemical localization of murine stage-specific embryonic antigens in human testicular germ cell tumors. Am J Pathol 108: 225-230, 1982. (Pubitemid 12051682)
16. Ohyama C, Fukushi Y, Satoh M, Saito S, Orikasa S, Nudelman E, Straud M and Hakomori S: Changes in glycolipid expression in human testicular tumor. Int J Cancer 45: 1040-1044, 1990. (Pubitemid 20201572)
17. Kang JL, Rajpert-De Meyts E, Wiels J and Skakkebaek NE: Expression of the glycolipid globotriaosylceramide (Gb3) in testicular carcinoma in situ. Virchows Arch 426: 369-374, 1995.
18. Ohyama C, Orikasa S, Kawamura S, Satoh M, Saito S, Fukushi Y, Levery SB and Hakomori S: Galactosylgloboside expression in seminoma. Inverse correlation with metastatic potential. Cancer 76: 1043-1050, 1995.
19. Wenk J, Andrews PW, Casper J, Hata J, Pera MF, von Keitz A, Damajanov I and Fenderson BA: Glycolipids of germ cell tumors: extended globo-series glycolipids are a hallmark of human embryonal carcinoma cells. Int J Cancer 58: 108-115, 1994. (Pubitemid 24213977)
20. Olie RA, Fenderson BA, Daley K, Oosterhuis JW, Murphy J and Looijienga LHJ: Glycolipids of human primary testicular germ cell tumours. Br J Cancer 74: 133-140, 1996. (Pubitemid 26231991)
21. Fenderson BA, Eddy EM and Hakomori S: Glycoconjugate expression during embryogenesis and its biological significance. Bioessays 12: 173-179, 1990. (Pubitemid 120034352)
22. Shevinsky LH, Knowles BB, Damajanov I and Solter D: Monoclonal antibody to murine embryos defines a stage-specific embryonic antigen on mouse embryos and human teratocarcinoma cells. Cell 30: 697-705, 1982. (Pubitemid 13204659)
23. Kannagi R, Cochran NA, Ishigami F, Hakomori S, Andrews PW, Knowles BB and Solter D: Stage-specific embryonic antigens (SSEA-3 and -4) are epitopes of a unique globo-series ganglioside isolated from human teratocarcinoma cells. EMBO J 2: 2355-2361, 1983.
24. Saito S, Levery SB, Salyan MEK, Goldberg RI and Hakomori S: Common tetrasaccharide epitope NeuAcα2-→3Galß1- →3(NeuAcα2→6)GalNAc, presented by different carrier glycosylceramide or O-linked peptides, is recognized by different antibodies and ligands having distinct specificities. J Biol Chem 269: 5644-5652, 1994.
25. Boden G and Gibb R: Radiotherapy and testicular neoplasms. Lancet 261: 1195-1197, 1951.
26. Folch J, Less M and Sloane Stanley GH: A simple method for the isolation and purification of total lipid from animal tissues. J Biol Chem 226: 497-509, 1957.
27. Beckstead JH: Alkaline phosphatase histochemistry in human germ cell neoplasms. Am J Surg Pathol 7: 341-349, 1983.
28. Burke AP and Mostofi FK: Intratubular malignant germ cells in testicular biopsies: clinical course and identification by staining for placental alkaline phosphatase. Mod Pathol 1: 475-479, 1988.
29. Giwercman A, Andrews PW, Jorgensen N, Müller J, Graem N and Skakkebaek NE: Immunohistochemical expression of embryonal marker TRA-1-60 in carcinoma in situ and germ cell tumors of the testis. Cancer 72: 1308-1314, 1993. (Pubitemid 23225001)
30. Rajpert-De Meyts and Skakkebaek NE: Expression of the c-kit protein in carcinoma-in situ and invasive testicular germ cell tumours. Int J Androl 17: 85-92, 1994.
31. Kojima Y, Fukumoto S, Furukawa K, Okajima T, Wiels J, Yokoyama K, Suzuki Y, Urano T, Ohta M and Furukawa K: Molecular cloning of globotriaosylceramide/ CD77 synthase, a glycosyltransferase that initiates the synthesis of globo series glycosphingolipids. J Biol Chem 275: 15152-15156, 2000. (Pubitemid 30337238)
32. Zhou D, Henion TR, Jungalwala FB, Berger EG and Hennet T: The β1,3-galactosyltransferase b3GalT-V is a stage-specific embryonic antigen-3 (SSEA-3) synthase. J Biol Chem 275: 22631-22634, 2000. (Pubitemid 30646144)
33. Saito S, Orikasa S, Satoh M, Ohyama C, Ito A and Takahashi T: Expression of globo-series gangliosides in human renal cell carcinoma. Jpn J Cancer Res 88: 652-659, 1997. (Pubitemid 27394049)
34. Fukushi Y, Ohtani H and Orikasa S: Expression of lacto-series type 2 antigens in human renal cell carcinoma and its clinical significance. J Natl Cancer Inst 81: 352-358, 1989. (Pubitemid 19065068)
35. Thompson JA, Kalishman J, Golos TG, Durning M, Harris CP, Becker RA and Hearn JP: Isolation of a primate embryonic stem cell line. Proc Natl Acad Sci USA 92: 7844-7848, 1995.
36. Shamblott MJ, Axelman J, Wang S, Bugg EM, Littlefield JW, Donovan PJ, Blumenthal PD, Huggins GR and Gearhart JD: Derivation of pluripotent stem cells from cultured human primordial germ cells. Proc Natl Acad Sci USA 95: 13726-13731, 1988.