Preparation of a water-in-oil-in-water (w/o/w) type microcapsules by a single-droplet-drying method and change in encapsulation efficiency of a hydrophilic substance during storage

Bioscience, Biotechnology and Biochemistry

Volumn 67, Issue 6, 2003, Pages 1376-1381

  Adachi, Shuji ^a   Imaoka, Hanaho ^a   Hasegawa, Yuri ^a   Matsuno, Ryuichi ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Encapsulation efficiency; Microcapsule; Microencapsulation; Water in oil in water (W O W) emulsion

Indexed keywords

ACACIA SENEGAL;

1,3,6,8 PYRENE TETRASULFONATE; 1,3,6,8-PYRENE TETRASULFONATE; OCTANOIC ACID DERIVATIVE; OIL; OLIVE OIL; POLYSACCHARIDE; PYRENE DERIVATIVE; TRIACYLGLYCEROL; TRIOCTANOIN; VEGETABLE OIL; WATER;

ARTICLE; CHEMISTRY; DRUG FORMULATION; DRUG STORAGE; ELECTRICITY; EMULSION; METHODOLOGY; MICROCAPSULE; STANDARD; SYNTHESIS; TECHNIQUE;

CAPSULES; DRUG COMPOUNDING; DRUG STORAGE; ELECTROSTATICS; EMULSIONS; METHODS; OCTANOIC ACIDS; OILS; PLANT OILS; POLYSACCHARIDES; PYRENES; TRIGLYCERIDES; WATER;

EID: 2142803675     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.67.1376     Document Type: Article

References (11)

1. Nakhara, S., and Vyas, S. P., Prolonged release of diclofenac sodium from multiple w/o/w emulsion systems. Pharmazie, 49, 842-845 (1994).
2. Sela, Y., Magdassi, S., and Garti, N., Release of markers from the inner water phase of W/O/W emulsions stabilized by silicone-based polymeric surfactants. J. Controlled Release, 33, 1-12 (1995).
3. Cunha, S. A., Grossiord, J. L., Puisieu, F., and Seiller, M., Insulin in wjo/w multiple emulsions: preparation, characterization and determination of stability towards proteases in vitro. J. Microencapsulation, 14, 311-319 (1997).
4. Ww and w/o/w emulsifications as preparation methods. J. Microencapsulation, 15, 185-195 (1998).
5. Muranishi, S., Absorption enhancers. Crit. Rev. Ther. Drug., 7, 1-33 (1990).
6. Musashino, K., Hasegawa, Y., Imaoka, H., Adachi, S., and Matsuno, R., Preparation of W/O/W multiple emulsions with polymers in the outer aqueous phase. Food Sci. Technol. Res., 7, 78-83 (2001).
7. Charlesworth, D. H., and Marshall, W. R. Jr., Evaporation from drops containing dissolved solids. AIChEJ, 6, 9-23 (1960).
8. Tokgoz, N. S., Grossiord, J. L., Fructus, A., Seiller, M., and Prognon, P., Evaluation of two fluorescent probes for the characterization of W/O/W emulsions. Int. J. Pharm., 141, 27-37 (1996).
9. Rockland, L. B., Saturated salt solutions for static control of relative humidity between 5° and 40°C. Anal. Chem., 32, 1375-1376 (1960).
10. Minemoto, Y., Adachi, S., and Matsuno, R., Comparison of oxidation of methyl linoleate encapsulated with gum aarabic by hot-air-drying and freeze-drying. J. Agric. Food Chem., 45, 4530-4534 (1997).
11. “Yushikagaku Binran”, Japan Oil Chemists’ Society, Maruzen, Tokyo, p. 104 (1990).