Preparation of W/O/W Multiple Emulsions with Polymers in the Outer Aqueous Phase

Food Science and Technology Research

Volumn 7, Issue 1, 2001, Pages 78-83

  Musashino, Kaoru ^a   Hasegawa, Yuri ^a   Imaoka, Hanaho ^a   Adachi, Shuji ^a   Matsuno, Ryuichi ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Encapsulation efficiency; Polymer; Surfactant; W O W emulsion

Indexed keywords

ACACIA SENEGAL; GLYCINE MAX;

EID: 0347663583     PISSN: 13446606     EISSN: None     Source Type: Journal    
DOI: 10.3136/fstr.7.78     Document Type: Article

References (11)

1. Giunchedi, R, Alpar, H.O. and Conte, U. (1998). PDLLA microspheres containing steroids: spray-drying, o/w and w/o/w emulsifications as preparation methods. J. Microencapsulation, 15, 185-195.
2. Matsuzawa, A., Morishita, M., Takayama, K. and Nagai, T. (1995). Absorption of insulin using water-in-oil-in-water emulsion from an enterai loop in rats. Biol. Pharm. Bull., 18, 1718-1723.
3. Nakhare, S. and Vyas, S.P. (1994). Prolonged release of diclofenac sodium from multiple w/o/w emulsion systems. Pharmazie, 49, 842-845.
4. Okochi, H. and Nakano, M. (1996). Basic studies on formulation, method of preparation and characterization of water-in-oil-in-water type multiple emulsions containing vancomycin. Chem. Pharm. Bull., 44, 180-186.
5. Sekine, M., Sasahara, K., Kojima, T., Hasegawa, K., Okada, R. and Awazu, S. (1984). Improvement of bioavailability of poorly absorbed drugs. I. Effect of medium chain glyceride base on the rectal absorption of cefmetazole sodium in rats. J. Pharm. Dyn., 7, 856-863.
6. Shima, M., Yohdou, K., Yamaguchi, M., Kimura, Y., Adachi, S. and Matsuno, R. (1997), Effects of medium chain fatty acids and their acylglycerols on transport of penicillin V across Caco-2 cell monolayers. Biosci. Biotechnol. Biochem., 61, 1150-1155.
7. Silva Cunha, A., Grossiord, J.L., Puisieux, F. and Seiller, M. (1997). Insulin in w/o/w multiple emulsions: preparation, characterization and determination of stability towards proteases in vitro. J. Microencapsulation 14, 311-319.
8. Tokgoz, N.S., Grossiord, J.L., Fructus, A., Seiller, M. and Prognon, P. (1996). Evaluation of two fluorescent probes for the characterizaion of W/O/W emulsions. Int. J. Pharm., 141, 27-37.
9. Uchida, T., Nagareya, N., Sakakibara S., Konishi, Y., Nakai, A., Nishikata., M., Matsuyama, K. and Yoshida, K. (1997). Preparation and characterization of polylactic acid microspheres containing bovine insulin by a w/o/w emulsion solvent evaporation method. Chem. Pharm. Bull., 45, 1539-1543.
10. Uno, T., Yamaguchi, T., Li, X.K., Suzuki, Y., Hashimoto, H., Harada, Y., Kimura, T. and Kazui, T. (1997). The pharmacokinetics of water-in-oil-in-water-type multiple emulsion of a new tacrolimus formulation. Lipids, 32, 543-548.
11. Yan, C., Resau, J.H., Hewetson, J., West, M., Rill, W.L. and Kende, M. (1994). Characterization and morphological analysis of protein-loaded poly(lactide-co-glycolide) microparticles prepared by water-in-oil-in-water emulsion technique. J. Control. Release, 32, 231-241.