Prolonged opportunity for ischemic neuroprotection with selective κ-opioid receptor agonist in rats

Stroke

Volumn 35, Issue 5, 2004, Pages 1180-1185

  Chen, Tsung Ying ^a   Goyagi, Toru ^a   Toung, Thomas J K ^a   Kirsch, Jeffrey R ^a,b   Hurn, Patricia D ^a,b   Koehler, Raymond C ^a   Bhardwaj, Anish ^a,c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

Infarct; Ischemia; Kappa(1) opioid receptors; Neuroprotection; Reperfusion

Indexed keywords

1 (3,4 DICHLOROPHENYL)ACETYL 2 (1 PYRROLIDINYL)METHYLPIPERIDINE; BRL 52537; DOPAMINE; KAPPA OPIATE RECEPTOR AGONIST; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANESTHESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; CORPUS STRIATUM; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; EXTRACELLULAR SPACE; IN VIVO STUDY; INFUSION; MALE; MICRODIALYSIS; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RANDOMIZATION; RAT; REPERFUSION; TRANSIENT ISCHEMIC ATTACK; TREATMENT OUTCOME;

ANIMALS; BRAIN ISCHEMIA; CEREBRAL CORTEX; CORPUS STRIATUM; DOPAMINE; ISCHEMIC ATTACK, TRANSIENT; MICRODIALYSIS; NEUROPROTECTIVE AGENTS; PIPERIDINES; PYRROLIDINES; RANDOM ALLOCATION; RATS; RATS, WISTAR; RECEPTORS, OPIOID, KAPPA; REPERFUSION INJURY;

EID: 2142698060     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.0000125011.93188.c6     Document Type: Article

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