Study on polymethacrylate nanoparticles as delivery system of antisense oligodeoxynucleotides

Yaoxue Xuebao

Volumn 38, Issue 4, 2003, Pages 298-301

  Wang, Wen Xi ^a   Chen, Hai Liang ^a   Liang, Wen Quan ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Antisense oligodeoxynucleotides; Delivery system; Nanoparticles; Polymethacrylate

Indexed keywords

ACRYLIC ACID RESIN; ANTISENSE OLIGONUCLEOTIDE; DRUG CARRIER; EUDRAGIT RS;

ANIMAL; ARTICLE; CHEMISTRY; DRUG DELIVERY SYSTEM; DRUG EFFECT; HEMOLYSIS; METHODOLOGY; NANOTECHNOLOGY; PARTICLE SIZE; PHARMACEUTICS;

ACRYLIC RESINS; ANIMALS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HEMOLYSIS; NANOTECHNOLOGY; OLIGONUCLEOTIDES, ANTISENSE; PARTICLE SIZE; TECHNOLOGY, PHARMACEUTICAL;

EID: 2142688126     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Saghir A, Marcus DH, Alim K, et al. The delivery of antisense therapeutics[J]. Adv Drug Deliv Rev,2000,44(1):3-21.
2. Irina L, Lyuba B, Stein CA, et al. Cellular delivery of antisense oligonucleotides[J]. Eur J Pharm Biopharm, 2000,50(1):101-119.
3. Keith J, Miller, Sudip KD. Antisense oligonucleotides: strategies for delivery[J]. Pharm Sci Tech Today,1998,1(9):377-386.
4. Gregory L, Elias F, Patrick C. Nanoparticulate systems for the delivery of antisense oligonucleotides[J]. Adv Drug Deliv Rev,2001,47(1): 99-112.
5. Lappalainen K, Jaaskelainen I, Syrjanen K, et al. Comparison of cell proliferation and toxicity assays using two cationic liposomes[J]. Pharm Res,1994,11(8):1127-1131.
6. Bragadin M, Antone P. Mitochondrial bioenergetics as affected by cationic detergents[J]. Arch Environm Contam Toxicol,1996,30(2):280-284.
7. Zobel HP, StienekerF, Atmaca-Abdel AS, et al. Evaluation of aminoalkylmethacrylate nanoparticles as colloidal drug carrier systems. Part II: characterization of antisense oligonucleotides loaded copolymer nanoparticles[J]. Eur J Pharm Biopharm,1999,48(1):1-12.
8. Earvin L, Maria N, Preeti S, et al. Biodegradable pH-sensitive surfactants (BPS) in liposome-mediated nucleic acid cellular uptake and distribution[J]. Eur J Pharm Sci,2000,11(2):199-205.
9. Qiang H, Clifford R, Marcel B, et al. Programmable fusogenic vesicles for intracellular delivery of antisense oligodeoxynucleotides: enhanced cellular uptake and biological effects. Biochim Biophys Acta,2001, 1514(1):1-13.