The ultrastructure of human tubulo-interstitial fibrosis

Journal of Submicroscopic Cytology and Pathology

Volumn 35, Issue 2, 2003, Pages 147-160

  Ru, Y ^a   Eyden, B ^a  

^a CHRISTIE HOSPITAL   (United Kingdom)

Author keywords

Human; Kidney; Tubulo interstitial fibrosis; Ultrastructure

Indexed keywords

ACTIN FILAMENT; CELL INFILTRATION; CHRONIC KIDNEY DISEASE; EXTRACELLULAR MATRIX; FIBROSING ALVEOLITIS; INFLAMMATORY CELL; KIDNEY FAILURE; LEUKOCYTE; MESENCHYME; REVIEW; ULTRASTRUCTURE; ELECTRON MICROSCOPY; EPITHELIUM CELL; FIBROSIS; HUMAN; INTERSTITIAL NEPHRITIS; KIDNEY TUBULE; PATHOLOGY;

EPITHELIAL CELLS; FIBROSIS; HUMANS; KIDNEY TUBULES; MICROSCOPY, ELECTRON; NEPHRITIS, INTERSTITIAL;

EID: 2142663198     PISSN: 11229497     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (26)

1. BADID C., VINCENT M., FOUQUE D., LAVILLE M. and DESMOULIERE A., 2001. Myofibroblast: a prognostic marker and target cell in progressive renal disease. Ren. Fail., 23, 543-549.
2. BRITO P.L., FIORETTO P., DRUMMOND K., KIM Y., STEFFES M., BASGEN J.M., SISSON-ROSS S. and MAUER M., 1998. Proximal tubular basement membrane width in insulin-dependent diabetes mellitus. Kidney Int., 53, 754-761.
3. BUTKOWSKI R.J., CARONE F.A., GRANTHAM J.J. and HUDSON B.G., 1985. Tubular basement membrane changes in 2-amino-4, 5-diphenylthiazole-induced polycystic disease. Kidney Int., 28, 744-751.
4. CHOI Y.J., CHAKRABORTY S., NGUYEN V., NGUYEN C., KIM B.K., SHIM S.I., SUKI W.N. and TRUONG L.D., 2000. Peritubular capillary loss is associated with chronic tubulointerstitial injury in human kidney: altered expression of vascular endothelial growth factor. Hum. Pathol., 31, 1491-1497.
5. CREELY J.J., DIMARI S.J., HOWE A.M. and HARALSON M.A., 1992. Effects of transforming growth factor-beta on collagen synthesis by normal rat kidney epithelial cells. Am. J. Pathol., 140, 45-55.
6. DIXON A.J., WINEARLS C.G. and DUNNILL M.S., 1981. Interstitial nephritis. J. Clin. Pathol., 34, 616-624.
7. EYDEN B., 2000. Smooth-muscle-type myofilaments and actin in reactive and neoplastic nonmuscle cells. Ultrastruct. Pathol., 24, 347-351.
8. EYDEN B., 2001. The myofibroblast: an assessment of controversial issues and a definition useful in diagnosis and research. Ultrastruct. Pathol., 25, 39-50.
9. JINDE K., NIKOLIC-PATERSON D.J., HUANG X.R., SAKAI H., KUROKAWA K., ATKINS R. C. and LAN H.Y., 2001. Tubular phenotypic change in progressive tubulointerstitial fibrosis in human glomerulonephritis. Am. J. Kidney Dis., 38, 761-769.
10. LI Y. and HUARD J., 2002. Differentiation of muscle-derived cells into myofibroblasts in injured skeletal muscle. Am. J. Pathol., 161, 895-907.
11. MØLLER J.C., SKRIVER E., OLSEN S. and MAUNSBACH A.B., 1984. Ultrastructural analysis of human proximal tubules and cortical interstitium in chronic renal disease (hydronephrosis). Virchows Arch. A Pathol. Anat. Histopathol., 402, 209-237.
12. MØLLER J.C. and SKRIVER E., 1985. Quantitative ultrastructure of human proximal tubules and cortical interstitium in chronic renal disease (hydronephrosis). Virchows Arch. A Pathol. Anat. Histopathol., 406, 389-406.
13. NG Y.Y., HUANG T.P., YANG W.C., CHEN Z.P., YANG A.H., MU W., NIKOLIC-PATERSON D.J., ATKINS R.C. and LAN H.Y., 1998. Tubular epithelial-myofibroblast transdifferentiation in progressive tubulointerstitial fibrosis in 5/6 nephrectomized rats. Kidney Int., 54, 864-876.
14. OHASHI R., KITAMURA H. and YAMANAKA N., 2000. Peritubular capillary injury during the progression of experimental glomerulonephritis in rats. J. Am. Soc. Nephrol., 11, 47-56.
15. OLSEN T.S., OLSEN H.S. and HANSEN H.E., 1984. Hypertrophy of actin bundles in tubular cells in acute renal failure. Ultrastruct. Pathol., 7, 241-250.
16. OLSEN T.S., WASSEF N.F., OLSEN H.S. and HANSEN H.E., 1986. Ultrastructure of the kidney in acute interstitial nephritis. Ultrastruct. Pathol., 10, 1-16.
17. OLSEN T.S. and HANSEN H.E., 1990. Ultrastructure of medullary tubules in ischemic acute tubular necrosis and acute interstitial nephritis in man. APMIS, 98, 1139-1148.
18. PORT F.K., FENTON S.S.A. and MAZZUCHI N., 2000. ESRD throughout the world: morbidity, mortality and quality of life. Kidney Int., 57, S1-S2.
19. RACUSEN L.C., 1994. Cell shape changes and detachment in cell culture: models of renal injury. Nephrol. Dial. Transplant., 4 (Suppl.), 4, 22-25.
20. REMUZZI G., RUGGENENTI P. and BENIGNI A., 1997. Understanding the nature of renal disease progression. Kidney Int., 51, 2-15.
21. SINNIAH R. and KHAN T.N., 1999. Renal tubular basement membrane changes in tubulointerstitial damage in patients with glomerular diseases. Ultrastruct. Pathol., 23, 359-368.
22. SOLEZ K., MOREL-MAROGER L. and SRAER J.D., 1979. The morphology of 'acute tubular necrosis' in man: analysis of 57 renal biopsies and a comparison with the glycerol model. Medicine (Baltimore), 58, 362-376.
23. STRUTZ F. and MULLER G.A., 1999. Interstitial pathomechanisms underlying progressive tubulointerstitial damage. Kidney Blood Press. Res., 22, 71-80.
24. SUZUKI T., KIMURA M., ASANO M., FUJIGAKI Y. and HISHIDA A., 2001. Role of atrophic tubules in development of interstitial fibrosis in microembolism-induced renal failure in rat. Am. J. Pathol., 158, 75-85.
25. YANG J. and LIU Y., 2001. Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis. Am. J. Pathol , 159, 1465-1475.
26. YANG J. and LIU Y., 2002. Blockage of tubular epithelial to myofibroblast transition by hepatocyte growth factor prevents renal interstitial fibrosis. J. Am. Soc. Nephrol., 13, 96-107.