-
1
-
-
0024026298
-
The triumvirate: Beta-cells, muscles, liver. A collusion responsible for NIDDM
-
DeFronzo RA. The triumvirate: beta-cells, muscles, liver. A collusion responsible for NIDDM. Diabetes 1988;37:667-87.
-
(1988)
Diabetes
, vol.37
, pp. 667-687
-
-
DeFronzo, R.A.1
-
2
-
-
0028280830
-
Overnight glucose metabolism in obese non-insulin-dependent diabetic patients and in healthy lean individuals
-
Tappy L, Acheson K, Curchod B, Schneiter Ph, Normand S, Pachiaudi C, et al. Overnight glucose metabolism in obese non-insulin-dependent diabetic patients and in healthy lean individuals. Clin Physiol 1994;14:251-65.
-
(1994)
Clin Physiol
, vol.14
, pp. 251-265
-
-
Tappy, L.1
Acheson, K.2
Curchod, B.3
Schneiter, Ph.4
Normand, S.5
Pachiaudi, C.6
-
3
-
-
0030988702
-
Evidence of increased systemic glucose production and gluconeogenesis in an early stage of NIDDM
-
Perriello G, Pampanelli S, Del Sindaco P, Lalli C, Ciofetta M, Volpi E, et al. Evidence of increased systemic glucose production and gluconeogenesis in an early stage of NIDDM. Diabetes 1997;46:1010-6.
-
(1997)
Diabetes
, vol.46
, pp. 1010-1016
-
-
Perriello, G.1
Pampanelli, S.2
Del Sindaco, P.3
Lalli, C.4
Ciofetta, M.5
Volpi, E.6
-
4
-
-
0024511329
-
Predominant role of gluconeogenesis in increased hepatic glucose production in NIDDM
-
Consoli A, Nurjhan N, Capani F, Gerich JE. Predominant role of gluconeogenesis in increased hepatic glucose production in NIDDM. Diabetes 1990;38:550-61.
-
(1990)
Diabetes
, vol.38
, pp. 550-561
-
-
Consoli, A.1
Nurjhan, N.2
Capani, F.3
Gerich, J.E.4
-
5
-
-
0025779624
-
Is muscle the major site of insulin resistance in type 2 (non-insulin-dependent) diabetes mellitus?
-
Gerich JE. Is muscle the major site of insulin resistance in type 2 (non-insulin-dependent) diabetes mellitus? Diabetologia 1991;34:607-10.
-
(1991)
Diabetologia
, vol.34
, pp. 607-610
-
-
Gerich, J.E.1
-
6
-
-
0031952156
-
Non-invasive tracing of liver intermediary metabolism in normal subjects and in moderately hyperglycemic NIDDM subjects. Evidence against increased gluconeogenesis and hepatic fatty acid oxidation in NIDDM
-
Diraison F, Large V, Brunengraber H, Beylot M. Non-invasive tracing of liver intermediary metabolism in normal subjects and in moderately hyperglycemic NIDDM subjects. Evidence against increased gluconeogenesis and hepatic fatty acid oxidation in NIDDM. Diabetologia 1998;41:212-20.
-
(1998)
Diabetologia
, vol.41
, pp. 212-220
-
-
Diraison, F.1
Large, V.2
Brunengraber, H.3
Beylot, M.4
-
7
-
-
0028558591
-
Relationship between hepatic glucose production and fasting plasma glucose concentration in patients with NIDDM
-
Jeng CY, Sheu WHH, Fuh MMT, Chen YD, Reaven GM. Relationship between hepatic glucose production and fasting plasma glucose concentration in patients with NIDDM. Diabetes 1994;43:1440-4.
-
(1994)
Diabetes
, vol.43
, pp. 1440-1444
-
-
Jeng, C.Y.1
Sheu, W.H.H.2
Fuh, M.M.T.3
Chen, Y.D.4
Reaven, G.M.5
-
8
-
-
0023692619
-
Relationship between plasma glucose and insulin concentration, glucose production, and glucose disposal in normal subjects and in patients with non-insulin-dependent diabetes
-
Chen YD, Jeng CY, Hollenbeck CB, Wu MS, Reaven GM. Relationship between plasma glucose and insulin concentration, glucose production, and glucose disposal in normal subjects and in patients with non-insulin-dependent diabetes. J Clin Invest 1988;82:21-5.
-
(1988)
J Clin Invest
, vol.82
, pp. 21-25
-
-
Chen, Y.D.1
Jeng, C.Y.2
Hollenbeck, C.B.3
Wu, M.S.4
Reaven, G.M.5
-
9
-
-
0028181010
-
Pathogenesis of type 2 (non-insulin-dependent) diabetes mellitus: The role of skeletal muscle glucose uptake and hepatic glucose production in the development of hyperglycemia. A critical comment
-
Beck-Nielsen H, Hother-Nielsen O, Vaag A, Alford F. Pathogenesis of type 2 (non-insulin-dependent) diabetes mellitus: the role of skeletal muscle glucose uptake and hepatic glucose production in the development of hyperglycemia. A critical comment. Diabetologia 1994;37:217-21.
-
(1994)
Diabetologia
, vol.37
, pp. 217-221
-
-
Beck-Nielsen, H.1
Hother-Nielsen, O.2
Vaag, A.3
Alford, F.4
-
10
-
-
0025780748
-
Insulin resistance, but not basal rates of hepatic glucose production in patients with newly diagnosed mild diabetes mellitus
-
Hother-Nielsen O, Beck-Nielsen H. Insulin resistance, but not basal rates of hepatic glucose production in patients with newly diagnosed mild diabetes mellitus. Acta Endocrinol 1991;124:637-45.
-
(1991)
Acta Endocrinol
, vol.124
, pp. 637-645
-
-
Hother-Nielsen, O.1
Beck-Nielsen, H.2
-
11
-
-
0035011295
-
Gluconeogenesis in moderately and severely hyperglycemic patients with type 2 diabetes mellitus
-
Boden G, Chen X, Stein P. Gluconeogenesis in moderately and severely hyperglycemic patients with type 2 diabetes mellitus. Am J Physiol Endocrinol Metab 2001;280:E23-30.
-
(2001)
Am J Physiol Endocrinol Metab
, vol.280
-
-
Boden, G.1
Chen, X.2
Stein, P.3
-
12
-
-
0025630056
-
Mechanism of increased gluconeogenesis in non-insulin-dependent diabetes mellitus
-
Consoli A, Nurjhan N, Reilly JJ, Bier DM, Gerich JE. Mechanism of increased gluconeogenesis in non-insulin-dependent diabetes mellitus. J Clin Invest 1990;86:2038-45.
-
(1990)
J Clin Invest
, vol.86
, pp. 2038-2045
-
-
Consoli, A.1
Nurjhan, N.2
Reilly, J.J.3
Bier, D.M.4
Gerich, J.E.5
-
13
-
-
0026488079
-
Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study
-
Magnusson I, Rothman DL, Katz LD, Shulman RG, Shulman GI. Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study. J Clin Invest 1992;90:1323-7.
-
(1992)
J Clin Invest
, vol.90
, pp. 1323-1327
-
-
Magnusson, I.1
Rothman, D.L.2
Katz, L.D.3
Shulman, R.G.4
Shulman, G.I.5
-
14
-
-
0027164528
-
Dose-response effects of lactate infusions on gluconeogenesis from lactate in normal man
-
Jenssen T, Nurjhan N, Consoli A, Gerich JE. Dose-response effects of lactate infusions on gluconeogenesis from lactate in normal man. Eur J Clin Invest 1993;23:448-54.
-
(1993)
Eur J Clin Invest
, vol.23
, pp. 448-454
-
-
Jenssen, T.1
Nurjhan, N.2
Consoli, A.3
Gerich, J.E.4
-
15
-
-
50549202600
-
The glucose fatty-acid cycle: Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
-
Randle PJ, Garland PB, Hales CN, Newsholm EA. The glucose fatty-acid cycle: its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 1963;1:785-9.
-
(1963)
Lancet
, vol.1
, pp. 785-789
-
-
Randle, P.J.1
Garland, P.B.2
Hales, C.N.3
Newsholm, E.A.4
-
16
-
-
0015517384
-
Glucose-lactate interrelation in man
-
Kreisberg R. Glucose-lactate interrelation in man. N Engl J Med 1972;287:132-7.
-
(1972)
N Engl J Med
, vol.287
, pp. 132-137
-
-
Kreisberg, R.1
-
17
-
-
4243408699
-
Insulin inhibition of overnight glucose production and glucoseneogenesis from lactate in NIDDM
-
Yki-Järvinen H, Helve E, Sane T, Nurjahan N, Taskinen MR. Insulin inhibition of overnight glucose production and glucoseneogenesis from lactate in NIDDM. Am J Physiol 1989;256:E732-9.
-
(1989)
Am J Physiol
, vol.256
-
-
Yki-Järvinen, H.1
Helve, E.2
Sane, T.3
Nurjahan, N.4
Taskinen, M.R.5
-
18
-
-
0023260703
-
The pancreatic-adrenocortical-pituitary clamp technique for study of counter-regulation in humans
-
DeFeo PGM, Perriello M, Ventura P, Brunetti F, Santeusanio JJ, Gerich JE, et al. The pancreatic-adrenocortical-pituitary clamp technique for study of counter-regulation in humans. Am J Physiol 1987;252:E565-70.
-
(1987)
Am J Physiol
, vol.252
-
-
DeFeo, P.G.M.1
Perriello, M.2
Ventura, P.3
Brunetti, F.4
Santeusanio, J.J.5
Gerich, J.E.6
-
19
-
-
0025079179
-
Failure of substrate-induced gluconeogenesis to increase overall glucose appearance in normal man: Demonstration of hepatic autoregulation without a change in plasma glucose concentration
-
Jenssen T, Nurjahan N, Consoli A, Gerich JE. Failure of substrate-induced gluconeogenesis to increase overall glucose appearance in normal man: demonstration of hepatic autoregulation without a change in plasma glucose concentration. J Clin Invest 1990;86:489-97.
-
(1990)
J Clin Invest
, vol.86
, pp. 489-497
-
-
Jenssen, T.1
Nurjahan, N.2
Consoli, A.3
Gerich, J.E.4
-
20
-
-
0036739352
-
Autoregulation of endogenous glucose production during hyperglucagonemia
-
Toft I, Gerich JE, Jenssen T. Autoregulation of endogenous glucose production during hyperglucagonemia. Metabolism 2002;51:1128-34.
-
(2002)
Metabolism
, vol.51
, pp. 1128-1134
-
-
Toft, I.1
Gerich, J.E.2
Jenssen, T.3
-
21
-
-
0023589251
-
Role of hyperglucagonemia in maintenance of increased rates of hepatic glucose output in type II diabetics
-
Baron A, Schaeffer D, Shragg L, Kolterman OG. Role of hyperglucagonemia in maintenance of increased rates of hepatic glucose output in type II diabetics. Diabetes 1987;36:274-83.
-
(1987)
Diabetes
, vol.36
, pp. 274-283
-
-
Baron, A.1
Schaeffer, D.2
Shragg, L.3
Kolterman, O.G.4
-
22
-
-
0017166537
-
Effects of arterial versus venous sampling on analysis of glucose kinetics in man
-
McGuire EJ, Halderman J, Tobin R, Andres R, Berman ML. Effects of arterial versus venous sampling on analysis of glucose kinetics in man. J Appl Physiol 1976;41:565-73.
-
(1976)
J Appl Physiol
, vol.41
, pp. 565-573
-
-
McGuire, E.J.1
Halderman, J.2
Tobin, R.3
Andres, R.4
Berman, M.L.5
-
26
-
-
0017664756
-
C-peptide response to glucagon: A test for the residual beta-cell function in diabetes mellitus
-
Faber OK, Binder C. C-peptide response to glucagon: a test for the residual beta-cell function in diabetes mellitus. Diabetes 1977;26:605-10.
-
(1977)
Diabetes
, vol.26
, pp. 605-610
-
-
Faber, O.K.1
Binder, C.2
-
27
-
-
0000802118
-
Glucagon
-
Jaffe B, Behrman H, editors. New York, NY: Academic Press
-
Faloona G, Unger R. Glucagon. In Jaffe B, Behrman H, editors. Methods of hormone radioimmunoassay. New York, NY: Academic Press, 1974: 317-30.
-
(1974)
Methods of Hormone Radioimmunoassay
, pp. 317-330
-
-
Faloona, G.1
Unger, R.2
-
28
-
-
0001794671
-
Growth hormone
-
Jaffe B, Behrman H, editors. New York, NY: Academic Press
-
Peake G. Growth hormone. In Jaffe B, Behrman H, editors. Methods of hormone radioimmunoassay. New York, NY: Academic Press, 1974: 103-21.
-
(1974)
Methods of Hormone Radioimmunoassay
, pp. 103-121
-
-
Peake, G.1
-
29
-
-
78651144990
-
On the hormonal regulation of carbohydrate metabolism: Studies with 14C glucose
-
DeBodo RR, Steele N, Altszuler A, Dunn D, Bishop J. On the hormonal regulation of carbohydrate metabolism: studies with 14C glucose. Recent Prog Horm Res 1963;19:445-8.
-
(1963)
Recent Prog Horm Res
, vol.19
, pp. 445-448
-
-
DeBodo, R.R.1
Steele, N.2
Altszuler, A.3
Dunn, D.4
Bishop, J.5
-
30
-
-
0015308079
-
Determination of lactate kinetics in human analysis of data from single injection vs continuous infusion methods
-
Searle G, Cavalieu R. Determination of lactate kinetics in human analysis of data from single injection vs continuous infusion methods. Proc Soc Exp Biol Med 1972;139:1002-6.
-
(1972)
Proc Soc Exp Biol Med
, vol.139
, pp. 1002-1006
-
-
Searle, G.1
Cavalieu, R.2
-
31
-
-
0017337076
-
Gluconeogenesis: Methodological approaches in vivo
-
Chiasson J, Liljenquist JW, Lacy A, Jennings B, Cherrington A. Gluconeogenesis: methodological approaches in vivo. Fed Proc 1977;36:229-35.
-
(1977)
Fed Proc
, vol.36
, pp. 229-235
-
-
Chiasson, J.1
Liljenquist, J.W.2
Lacy, A.3
Jennings, B.4
Cherrington, A.5
-
32
-
-
0032529147
-
Regulation of endogenous glucose production by glucose per se is impaired in type 2 diabetes mellitus
-
Mevorach M, Giacca A, Aharon Y, Hawkins M, Shamoon H, Rosetti L. Regulation of endogenous glucose production by glucose per se is impaired in type 2 diabetes mellitus. J Clin Invest 1998;102:744-53.
-
(1998)
J Clin Invest
, vol.102
, pp. 744-753
-
-
Mevorach, M.1
Giacca, A.2
Aharon, Y.3
Hawkins, M.4
Shamoon, H.5
Rosetti, L.6
-
33
-
-
0023605591
-
Determination of Krebs cycle metabolic carbon exchange in vivo and its use to estimate the individual contributions of gluconeogenesis and glycogenolysis to overall glucose output in man
-
Consoli A, Kennedy F, Miles J, Gerich JE. Determination of Krebs cycle metabolic carbon exchange in vivo and its use to estimate the individual contributions of gluconeogenesis and glycogenolysis to overall glucose output in man. J Clin Invest 1987;80:1303-10.
-
(1987)
J Clin Invest
, vol.80
, pp. 1303-1310
-
-
Consoli, A.1
Kennedy, F.2
Miles, J.3
Gerich, J.E.4
-
34
-
-
0022048405
-
14C-labelled substrates
-
14C-labelled substrates. Am J Physiol 1986;248:R391-9.
-
(1986)
Am J Physiol
, vol.248
-
-
Katz, J.1
-
35
-
-
0020063476
-
Correction for the metabolic exchange of 14C for 12C in the pathway of gluconeogenesis in vivo
-
Hetenyi G Jr. Correction for the metabolic exchange of 14C for 12C in the pathway of gluconeogenesis in vivo. Federation Proc 1985;41:104-9.
-
(1985)
Federation Proc
, vol.41
, pp. 104-109
-
-
Hetenyi Jr., G.1
-
36
-
-
0025963777
-
The role of free fatty acid metabolism in the pathogenesis of insulin resistance in obesity and non-insulin-dependent diabetes mellitus
-
Groop LC, Saloranta C, Shank M, Bonnadonna RC, Ferrannini E, DeFronzo RA. The role of free fatty acid metabolism in the pathogenesis of insulin resistance in obesity and non-insulin-dependent diabetes mellitus. J Clin Endocrinol Metab 1991;72:96-107.
-
(1991)
J Clin Endocrinol Metab
, vol.72
, pp. 96-107
-
-
Groop, L.C.1
Saloranta, C.2
Shank, M.3
Bonnadonna, R.C.4
Ferrannini, E.5
DeFronzo, R.A.6
-
37
-
-
0019995650
-
Hepatic and peripheral insulin resistance: A common feature of type 2 (non-insulin-dependent) and type 1 (insulin-dependent) diabetes mellitus
-
DeFronzo RA, Simonson D, Ferrannini E. Hepatic and peripheral insulin resistance: a common feature of type 2 (non-insulin-dependent) and type 1 (insulin-dependent) diabetes mellitus. Diabetologia 1982;23:313-8.
-
(1982)
Diabetologia
, vol.23
, pp. 313-318
-
-
DeFronzo, R.A.1
Simonson, D.2
Ferrannini, E.3
-
38
-
-
0021691098
-
Relationship between insulin secretion, insulin action, and fasting plasma glucose concentration in non-diabetic and non-insulin-dependent diabetic subjects
-
Bogardius C, Lillioja S, Howard B, Reaven G, Mott D. Relationship between insulin secretion, insulin action, and fasting plasma glucose concentration in non-diabetic and non-insulin-dependent diabetic subjects. J Clin Invest 1984;74:1238-46.
-
(1984)
J Clin Invest
, vol.74
, pp. 1238-1246
-
-
Bogardius, C.1
Lillioja, S.2
Howard, B.3
Reaven, G.4
Mott, D.5
-
39
-
-
0029976176
-
Effects of ingested fructose and infused glucagon on endogenous glucose production in obese NIDDM patients, obese non-diabetic subjects, and healthy subjects
-
Paquot N, Schneiter Ph, Jèquier E, Gaillard R, Lefèbvre PJ, Scheen A, Tappy L. Effects of ingested fructose and infused glucagon on endogenous glucose production in obese NIDDM patients, obese non-diabetic subjects, and healthy subjects. Diabetologia 1996;39:580-6.
-
(1996)
Diabetologia
, vol.39
, pp. 580-586
-
-
Paquot, N.1
Schneiter, Ph.2
Jèquier, E.3
Gaillard, R.4
Lefèbvre, P.J.5
Scheen, A.6
Tappy, L.7
-
40
-
-
0025994801
-
No reduction in total hepatic glucose output by inhibition of gluconeogenesis with ethanol in NIDDM patients
-
Puhakainen I, Koivisto VA, Yki-Järvinen H. No reduction in total hepatic glucose output by inhibition of gluconeogenesis with ethanol in NIDDM patients. Diabetes 1991;40:1319-27.
-
(1991)
Diabetes
, vol.40
, pp. 1319-1327
-
-
Puhakainen, I.1
Koivisto, V.A.2
Yki-Järvinen, H.3
-
41
-
-
0027515569
-
Inhibition of lipolysis decreases lipid oxidation and gluconeogenesis from lactate, but not fasting hyperglycemia or total hepatic glucose production in NIDDM
-
Puhakainen I, Yki-Järvinen H. Inhibition of lipolysis decreases lipid oxidation and gluconeogenesis from lactate, but not fasting hyperglycemia or total hepatic glucose production in NIDDM. Diabetes 1993;42:1694-1699.
-
(1993)
Diabetes
, vol.42
, pp. 1694-1699
-
-
Puhakainen, I.1
Yki-Järvinen, H.2
-
43
-
-
0034034229
-
Glucose-6-phosphatase flux in vitro is increased in type 2 diabetes
-
Clore JN, Stillman J, Sugerman H. Glucose-6-phosphatase flux in vitro is increased in type 2 diabetes. Diabetes 2000;49:969-74.
-
(2000)
Diabetes
, vol.49
, pp. 969-974
-
-
Clore, J.N.1
Stillman, J.2
Sugerman, H.3
-
44
-
-
0028056913
-
Liver glycogen turnover in fed and fasted humans
-
Magnusson I, Rothman DL, Jucker B, Cline GW, Shulman RG, Shulman GI. Liver glycogen turnover in fed and fasted humans. Am J Physiol 1994;266:E796-803.
-
(1994)
Am J Physiol
, vol.266
-
-
Magnusson, I.1
Rothman, D.L.2
Jucker, B.3
Cline, G.W.4
Shulman, R.G.5
Shulman, G.I.6
-
45
-
-
0031713953
-
Regulation of glucose production by NEFA and gluconeogenic precursors during chronic glucagons infusion
-
McGuinness OP, Ejiofor J, Audoly LP, Schrom N. Regulation of glucose production by NEFA and gluconeogenic precursors during chronic glucagons infusion. Am J Physiol 1998;275:E432-9.
-
(1998)
Am J Physiol
, vol.275
-
-
McGuinness, O.P.1
Ejiofor, J.2
Audoly, L.P.3
Schrom, N.4
-
46
-
-
10644253401
-
The role of the carnitine system in human metabolism
-
Foster DW. The role of the carnitine system in human metabolism. Ann NY Acad Sci 2004;1033:1-16.
-
(2004)
Ann NY Acad Sci
, vol.1033
, pp. 1-16
-
-
Foster, D.W.1
-
47
-
-
0036312905
-
Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men
-
Seppälà-Lindroos A, Vehkavaara S, Hãkkinin AM, Goto T, Westerbacka J, Sovijãrvi A, Halavaara J, Yki-Jàrvinen H. Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men. J Clin Endocrinol Metabol 2002;87:3023-8.
-
(2002)
J Clin Endocrinol Metabol
, vol.87
, pp. 3023-3028
-
-
Seppälà-Lindroos, A.1
Vehkavaara, S.2
Hãkkinin, A.M.3
Goto, T.4
Westerbacka, J.5
Sovijãrvi, A.6
Halavaara, J.7
Yki-Jàrvinen, H.8
-
48
-
-
0242696221
-
Lipid overload and overflow: Metabolic trauma and the metabolic syndrome
-
Unger RH. Lipid overload and overflow: metabolic trauma and the metabolic syndrome. Trends Endocrinol Metab 2003;14:398-403.
-
(2003)
Trends Endocrinol Metab
, vol.14
, pp. 398-403
-
-
Unger, R.H.1
-
49
-
-
0028961526
-
Contribution of hepatic glycogenolysis to glucose production in response to a physiological increase in plasma glucagons
-
Magnusson I, Rothman DL, Gerard DP, Katz LD, Shulman GI. Contribution of hepatic glycogenolysis to glucose production in response to a physiological increase in plasma glucagons. Diabetes 1995;44:185-9.
-
(1995)
Diabetes
, vol.44
, pp. 185-189
-
-
Magnusson, I.1
Rothman, D.L.2
Gerard, D.P.3
Katz, L.D.4
Shulman, G.I.5
-
50
-
-
0002626606
-
Hormonal and substrate determinants of hepatic glucose production in man
-
Veneziale CM, editor. Baltimore: BA, University Park Press
-
Gerich JE. Hormonal and substrate determinants of hepatic glucose production in man. In Veneziale CM, editor. The regulation of carbohydrate formation and utilization in mammals. Baltimore: BA, University Park Press, 1981: 419-57.
-
(1981)
The Regulation of Carbohydrate Formation and Utilization in Mammals
, pp. 419-457
-
-
Gerich, J.E.1
-
51
-
-
0023900118
-
Hormonal control of substrate cycling in humans
-
Miyoshi H, Shulman GI, Peters EJ, Wolfe MH, Elahi D, Wolfe RR. Hormonal control of substrate cycling in humans. J Clin Invest 1988;81:1545-55.
-
(1988)
J Clin Invest
, vol.81
, pp. 1545-1555
-
-
Miyoshi, H.1
Shulman, G.I.2
Peters, E.J.3
Wolfe, M.H.4
Elahi, D.5
Wolfe, R.R.6
|