Expression of c-kit messenger ribonucleic acid and c-kit protein in sigmoid colon of patients with slow transit constipation

International Journal of Colorectal Disease

Volumn 20, Issue 4, 2005, Pages 363-367

  Tong, Wei Dong ^a   Liu, Bao Hua ^a   Zhang, Lian Yang ^a   Xiong, Ren Ping ^a   Liu, Ping ^a   Zhang, Sheng Ben ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

c kit; Etiology; Interstitial cells of Cajal; Slow transit constipation

Indexed keywords

MESSENGER RNA; STEM CELL FACTOR;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COLON RESECTION; COLORECTAL CANCER; CONSTIPATION; CONTROLLED STUDY; DEFECATION; DEFECOGRAPHY; FEMALE; HUMAN; HUMAN TISSUE; INTERSTITIAL CELL OF CAJAL; INTESTINE OBSTRUCTION; INTESTINE RADIOGRAPHY; MALE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SAMPLING; SIGMOID; SIGNAL TRANSDUCTION; SLOW TRANSIT CONSTIPATION; WESTERN BLOTTING;

ADULT; AGED; BLOTTING, WESTERN; CASE-CONTROL STUDIES; CONSTIPATION; FEMALE; GASTROINTESTINAL MOTILITY; GENE EXPRESSION PROFILING; HUMANS; MALE; MIDDLE AGED; PROTO-ONCOGENE PROTEINS C-KIT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 21344442656     PISSN: 01791958     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00384-004-0679-0     Document Type: Article

References (38)

1. Ward SM, Sanders KM (2001) Physiology and pathophysiology of the interstitial cell of Cajal: From bench to bedside. I. Functional development and plasticity of interstitial cells of Cajal networks. Am J Physiol Gasterointest Liver Physiol 281:G602-G611
2. Huizinga JD, Thuneberg L, Kluppel M, Malysz J, Mikkelsen HB, Bernstein A (1995) W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity. Nature 373:347-349 1:CAS:528:DyaK2MXjtlygur0%3D
3. Ward SM, Burns AJ, Torihashi S, Sanders KM (1994) Mutation of the proto-oncogene c-kit blocks development of interstitial cells and electrical rhythmicity in murine intestine. J Physiol 480:91-97 1:CAS:528:DyaK2cXmslOqt78%3D
4. Ward SM, Burns AJ, Torihashi S, Harney SC, Sanders KM (1995) Impaired development of interstitial cells and intestinal electrical rhythmicity in steel mutants. Am J Physiol 269:C1577-C1585
5. He CL, Burgart L, Wang L, Pemberton J, Young-Fadok T, Szurszewski J, Farrugia G (2000) Decreased interstitial cell of Cajal volume in patients with slow-transit constipation. Gastroenterology 118:14-21 14-21 1:STN:280:DC%2BD3c%2FnvFWitw%3D%3D
6. Lyford GL, He CL, Soffer E, Hull TL, Strong SA, Senagore AJ, Burgart LJ, Young-Fadok T, Szurszewski JH, Farrugia G (2002) Pan-colonic decrease in interstitial cells of Cajal in patients with slow transit constipation. Gut 51:496-501 10.1136/gut.51.4.496
7. Yu CS, Kim HC, Hong HK, Chung DH, Kim HJ, Kang GH, Kim JC (2002) Evaluation of myenteric ganglion cells and interstitial cells of Cajal in patients with chronic idiopathic constipation. Int J Colorectal Dis 17:253-258 10.1007/s00384-001-0380-5
8. Wedel T, Spiegler J, Soellner S, Roblick UJ, Schiedeck TH, Bruch HP, Krammer HJ (2002) Enteric nerves and interstitial cells of Cajal are altered in patients with slow-transit constipation and megacolon. Gastroenterology 123:1459-1467
9. Isozaki K, Hirota S, Miyagawa J, Taniguchi M, Shinomura Y, Matsuzawa Y (1997) Deficiency of c-kit+ cells in patients with a myopathic form of chronic idiopathic intestinal pseudo-obstruction. Am J Gastroenterol 92:332-334
10. Boeckxstaens GE, Rumessen JJ, de Wit L, Tytgat GN, Vanderwinden JM (2002) Abnormal distribution of the interstitial cells of Cajal in an adult patient with pseudo-obstruction and megaduodenum. Am J Gastroenterol 97:2120-2126
11. Taguchi T, Suita S, Masumoto K, Nada O (2003) Universal distribution of c-kit-positive cells in different types of Hirschsprung's disease. Pediatr Surg Int 19:273-279
12. Vanderwinden JM, Rumessen JJ, Liu H, Descamps D, De Laet MH, Vanderhaeghen JJ (1996) Interstitial cells of Cajal in human colon and in Hirschsprung's disease. Gastroenterology 111:901-910 1:STN:280:BymH38fkvVU%3D
13. Hagger R, Finlayson C, Kahn F, De Oliveira R, Chimelli L, Kumar D (2000) A deficiency of interstitial cells of Cajal in Chagasic megacolon. J Auton Nerv Syst 80:108-111 1:STN:280:DC%2BD3c3gvFegtQ%3D%3D
14. Porcher C, Baldo M, Henry M, Orsoni P, Jule Y, Ward SM (2002) Deficiency of interstitial cells of Cajal in the small intestine of patients with Crohn's disease. Am J Gastroenterol 97:118-125
15. He CL, Soffer EE, Ferris CD, Walsh RM, Szurszewski JH, Farrugia G (2001) Loss of interstitial cells of Cajal and inhibitory innervation in insulin-dependent diabetes. Gastroenterology 121:427-434
16. Nakahara M, Isozaki K, Hirota S, Vanderwinden JM, Takakura R, Kinoshita K, Miyagawa J, Chen H, Miyazaki Y, Kiyohara T, Shinomura Y, Matsuzawa Y (2002) Deficiency of KIT-positive cells in the colon of patients with diabetes mellitus. J Gastroenterol Hepatol 17:666-670 10.1046/ j.1440-1746.2002.02756.x
17. Torihashi S, Nishi K, Tokutomi Y, Nishi T, Ward S, Sanders KM (1999) Blockade of kit signaling induces transdifferentiation of interstitial cells of Cajal to a smooth muscle phenotype. Gastroenterology 117:140-148
18. Tong WD, Zhang SB, Zhang LY, Gao F (2004) Decreased interstitial cells of Cajal in the sigmoid colon of patients with slow transit constipation. Int J Colorectal Dis 19:467-473 10.1007/s00384-003-0577-x
19. Pehl C, Schmidt T, Schepp W (2002) Slow transit constipation: More than one disease? Gut 51:610; author reply 610 10.1136/gut.51.4.610
20. Knowles CH, Martin JE (2000) Slow transit constipation: A model of human gut dysmotility. Review of possible aetiologies. Neurogastroenterol Motil 12:181-196
21. Slater BJ, Varma JS, Gillespie JI (1997) Abnormalities in the contractile properties of colonic smooth muscle in idiopathic slow transit constipation. Br J Surg 84:181-184
22. Knowles CH, Scott SM, Lunniss PJ (2001) Slow transit constipation: A disorder of pelvic autonomic nerves? Dig Dis Sci 46:389-401 10.1023/ A:1005665218647
23. Sanders KM, Ordog T, Koh SD, Torihashi S, Ward SM (1999) Development and plasticity of interstitial cells of Cajal. Neurogastroenterol Motil 11:311-338 10.1046/j.1365-2982.1999.00164.x
24. Wu JJ, Rothman TP, Gershon MD (2000) Development of the interstitial cell of Cajal: Origin, kit dependence and neuronal and nonneuronal sources of kit ligand. J Neurosci Res 59:384-401 10.1002/ (SICI)1097-4547(20000201)59:3<384::AID-JNR13>3.0.CO;2-4
25. Sabri M, Barksdale E, Di Lorenzo C (2003) Constipation and lack of colonic interstitial cells of Cajal. Dig Dis Sci 48:849-853 10.1023/ A:1023074823778
26. Hirota S, Isozaki K, Nishida T, Kitamura Y (2000) Effects of loss-of-function and gain-of-function mutations of c-kit on the gastrointestinal tract. J Gastroenterol 35 [Suppl 12]:75-79
27. Kitamura Y, Hirota S, Nishida T (2001) A loss-of-function mutation of c-kit results in depletion of mast cells and interstitial cells of Cajal, while its gain-of-function mutation results in their oncogenesis. Mutat Res 477:165-171
28. Lecoin L, Gabella G, Le Douarin N (1996) Origin of the c-kit-positive interstitial cells in the avian bowel. Development 122:725-733
29. Rich A, Miller SM, Gibbons SJ, Malysz J, Szurszewski JH, Farrugia G (2003) Local presentation of steel factor increases expression of c-kit immunoreactive interstitial cells of Cajal in culture. Am J Physiol Gasterointest Liver Physiol 284:G313-G320
30. Smith B (1973) Pathologic changes in the colon produced by anthraquinone purgatives. Dis Colon Rectum 16:455-458
31. Smith B (1972) Pathology of cathartic colon. Proc R Soc Med 65:288
32. Muller-Lissner S (1996) What has happened to the cathartic colon? Gut 39:486-488
33. De Ponti F, De Giorgio R (2002) The cathartic colon? Aliment Pharmacol Ther 16:643-644 10.1046/j.1365-2036.2002.1193a.x
34. Joo JS, Ehrenpreis ED, Gonzalez L, Kaye M, Breno S, Wexner SD, Zaitman D, Secrest K (1998) Alterations in colonic anatomy induced by chronic stimulant laxatives: The cathartic colon revisited. J Clin Gastroenterol 26:283-286 10.1097/00004836-199806000-00014
35. Christensen J, Rick GA (1994) Interstitial cells of Cajal in the rat colon are damaged by mild hypoxia. J Auton Nerv Syst 48:175-180 10.1016/ 0165-1838(94)90033-7
36. Faussone-Pellegrini MS, Gay J, Vannucchi MG, Corsani L, Fioramonti J (2002) Alterations of neurokinin receptors and interstitial cells of Cajal during and after jejunal inflammation induced by Nippostrongylus brasiliensis in the rat. Neurogastroenterol Motil 14:83-95
37. Der T, Bercik P, Donnelly G, Jackson T, Berezin I, Collins SM, Huizinga JD (2000) Interstitial cells of Cajal and inflammation-induced motor dysfunction in the mouse small intestine. Gastroenterology 119:1590-1599 1:STN:280:DC%2BD3M%2Fnt1eqtA%3D%3D
38. Chang IY, Glasgow NJ, Takayama I, Horiguchi K, Sanders KM, Ward SM (2001) Loss of interstitial cells of Cajal and development of electrical dysfunction in murine small bowel obstruction. J Physiol 536:555-568 10.1111/j.1469-7793.2001.0555c.xd