Cloning an artificial gene encoding angiostatic anginex: From designed peptide to functional recombinant protein

Biochemical and Biophysical Research Communications

Volumn 333, Issue 4, 2005, Pages 1261-1268

  Brandwijk, Ricardo J M G E ^a   Nesmelova, Irina ^b   Dings, Ruud P M ^b   Mayo, Kevin H ^b   Thijssen, Victor L J L ^a   Griffioen, Arjan W ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Anginex; Angiogenesis; Endothelial cells; Functional characterization; Yeast expression system

Indexed keywords

ANGINEX; ANGIOSTATIC PROTEIN; DIMER; RECOMBINANT PROTEIN; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BETA SHEET; CELL GROWTH; CELL MIGRATION; CHICK EMBRYO; CHORIOALLANTOIS; CIRCULAR DICHROISM; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG SYNTHESIS; EMBRYO; ENDOTHELIUM CELL; FUNGAL STRAIN; GENE CONSTRUCT; GENE THERAPY; GENETIC CODE; GROWTH INHIBITION; HUMAN; HUMAN TISSUE; IN VIVO STUDY; MASS SPECTROMETRY; MOLECULAR CLONING; NONHUMAN; PHARMACOGENETICS; PICHIA PASTORIS; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN SYNTHESIS; STRUCTURE ACTIVITY RELATION;

ANGIOGENESIS INHIBITORS; CELLS, CULTURED; CLONING, MOLECULAR; ENDOTHELIAL CELLS; GENE TRANSFER TECHNIQUES; GENES, SYNTHETIC; HUMANS; NEOVASCULARIZATION, PHYSIOLOGIC; PICHIA; PROTEIN ENGINEERING; PROTEINS; RECOMBINANT PROTEINS;

PICHIA PASTORIS;

EID: 21344431613     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.06.029     Document Type: Article

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