Structural modification of plasma HDL by phospholipids promotes efficient ABCA1-mediated cholesterol release

Journal of Lipid Research

Volumn 46, Issue 7, 2005, Pages 1457-1465

  Hassan, Houssein Hajj ^a   Blain, Sacha ^a   Boucher, Betsie ^a   Denis, Maxime ^a   Krimbou, Larbi ^a   Genest, Jacques ^a  

^a ROYAL VICTORIA HOSPITAL   (Canada)

Author keywords

ATP binding cassette transporter A1; Cholesterol efflux; High density lipoprotein; Lipid poor apolipoprotein A I

Indexed keywords

ABC TRANSPORTER A1; APOLIPOPROTEIN A1; CHOLESTEROL; CYCLIC AMP; DIMYRISTOYLPHOSPHATIDYLCHOLINE; GLIBENCLAMIDE; HIGH DENSITY LIPOPROTEIN; IODINE 125; LIPOPROTEIN; PHOSPHOLIPID; VERY LOW DENSITY LIPOPROTEIN; ABC TRANSPORTER; HIGH DENSITY LIPOPROTEIN 3; LIPOSOME;

ANIMAL CELL; ARTICLE; ATHEROSCLEROSIS; CHEMICAL STRUCTURE; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; FOAM CELL; HUMAN; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; STRUCTURE ANALYSIS; VASCULAR DISEASE; ANIMAL; BLOOD; CELL CULTURE; CHEMISTRY; DRUG EFFECT; METABOLISM; SECRETION; TANGIER DISEASE;

ANIMALS; APOLIPOPROTEIN A-I; ATP-BINDING CASSETTE TRANSPORTERS; CELLS, CULTURED; CHOLESTEROL; DIMYRISTOYLPHOSPHATIDYLCHOLINE; HUMANS; LIPOPROTEINS, HDL; LIPOPROTEINS, HDL3; LIPOSOMES; MACROPHAGES; MALE; MICE; PHOSPHOLIPIDS; TANGIER DISEASE;

EID: 21244504555     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M400477-JLR200     Document Type: Article

References (35)

1. Brewer, H. B., Jr., and S. Santamarina-Fojo. 2003. New insights into the role of the adenosine triphosphate-binding cassette transporters in high-density lipoprotein metabolism and reverse cholesterol transport. Am. J. Cardiol. 91: 3E-11E.
2. Tall, A. R. 1993. Plasma cholesteryl ester transfer protein. J. Lipid Res. 34: 1255-1274.
3. Joyce, C. W., M. J. Amar, G. Lambert, B. L. Vaisman, B. Paigen, J. Najib-Fruchart, R. F. Hoyt, Jr., E. D. Neufeld, A. T. Remaley, D. S. Fredrickson, et al. 2002. The ATP binding cassette transporter A1 (ABCA1) modulates the development of aortic atherosclerosis in C57BL/6 and apoE-knockout mice. Proc. Natl. Acad. Sci. USA. 99: 407-412.
4. Marcil, M., R. Bissonnette, J. Vincent, L. Krimbou, and J. Genest. 2003. Cellular phospholipid and cholesterol efflux in high-density lipoprotein deficiency. Circulation. 107: 1366-1371.
5. Basso, F., L. Freeman, C. L. Knapper, A. Remaley, J. Stonik, E. B. Neufeld, T. Tansey, M. J. Amar, J. Fruchart-Najib, N. Duverger, et al. 2003. Role of the hepatic ABCA1 transporter in modulating intrahepatic cholesterol and plasma HDL cholesterol concentrations. J. Lipid Res. 44: 296-302.
6. Marcil, M., A. Brooks-Wilson, S. M. Clee, K. Roomp, L. H. Zhang, L. Yu, J. A. Collins, M. van Dam, H. O. Molhuizen, O. Loubster, et al. 1999. Mutations in the ABC1 gene in familial HDL deficiency with defective cholesterol efflux. Lancet. 354: 1341-1346.
7. Singaraja, R. R., L. R. Brunham, H. Visscher, J. J. Kastelein, and M. R. Hayden. 2003. Efflux and atherosclerosis: the clinical and biochemical impact of variations in the ABCA1 gene. Arterioscler. Thromb. Vasc. Biol. 23: 1322-1332.
8. Batal, R., M. Tremblay, L. Krimbou, O. Mamer, J. Davignon, J. Genest, Jr., and J. S. Cohn. 1998. Familial HDL deficiency characterized by hypercatabolism of mature apoA-I but not proapoA-I. Arterioscler. Thromb. Vasc. Biol. 18: 655-664.
9. Castro, G. R., and C. J. Fielding. 1988. Early incorporation of cell-derived cholesterol into pre-beta-migrating high-density lipoprotein. Biochemistry. 27: 25-29.
10. Kawano, M., T. Miida, C. J. Fielding, and P. E. Fielding. 1993. Quantitation of pre beta-HDL-dependent and nonspecific components of the total efflux of cellular cholesterol and phospholipid. Biochemistry. 32: 5025-5028.
11. Lefevre, M., C. H. Sloop, and P. S. Roheim. 1988. Characterization of dog prenodal peripheral lymph lipoproteins. Evidence for the peripheral formation of lipoprotein-unassociated apoA-I with slow pre-beta electrophoretic mobility. J. Lipid Res. 29: 1139-1148.
12. Hara, H., and S. Yokoyama. 1991. Interaction of free apolipoproteins with macrophages. Formation of high density lipoprotein-like lipoproteins and reduction of cellular cholesterol. J. Biol. Chem. 266: 3080-3086.
13. Francone, O. L., A. Gurakar, and C. Fielding. 1989. Distribution and functions of lecithin:cholesterol acyltransferase and cholesteryl ester transfer protein in plasma lipoproteins. Evidence for a functional unit containing these activities together with apolipoproteins A-I and D that catalyzes the esterification and transfer of cell-derived cholesterol. J. Biol. Chem. 264: 7066-7072.
14. Huang, Y., A. von Eckardstein, and G. Assmann. 1993. Cell-derived unesterified cholesterol cycles between different HDLs and LDL for its effective esterification in plasma. Arterioscler. Thromb. 13: 445-458.
15. Jian, B., M. Llera-Moya, L. Royer, G. Rothblat, O. Francone, and J. B. Swaney. 1997. Modification of the cholesterol efflux properties of human serum by enrichment with phospholipid. J. Lipid Res. 38: 734-744.
16. Krimbou, L., M. Marcil, H. Chiba, and J. Genest, Jr. 2003. Structural and functional properties of human plasma high density-sized lipoprotein containing only apoE particles. J. Lipid Res. 44: 884-892.
17. Krimbou, L., M. Marcil, J. Davignon, and J. Genest, Jr. 2001. Interaction of lecithin:cholesterol acyltransferase (LCAT).alpha 2-macroglobulin complex with low density lipoprotein receptor-related protein (LRP). Evidence for an alpha 2-macroglobulin/LRP receptor-mediated system participating in LCAT clearance. J. Biol. Chem. 276: 33241-33248.
18. Denis, M., B. Haidar, M. Marcil, M. Bouvier, L. Krimbou, and J. Genest, Jr. 2004. Molecular and cellular physiology of apolipoprotein A-I lipidation by the ATP-binding cassette transporter A1 (ABCA1). J. Biol. Chem. 279: 7384-7394.
19. Krimbou, L., M. Tremblay, H. Jacques, J. Davignon, and J. S. Cohn. 1998. In vitro factors affecting the concentration of gamma-LpE (gamma-LpE) in human plasma. J. Lipid Res. 39: 861-872.
20. Krimbou, L., M. Denis, B. Haidar, M. Carrier, M. Marcil, and J. Genest, Jr. 2004. Molecular interactions between apoE and ABCA1: impact on apoE lipidation. J. Lipid Res. 45: 839-848.
21. Denis, M., B. Haidar, M. Marcil, M. Bouvier, L. Krimbou, and J. Genest. 2004. Characterization of oligomeric human ATP binding cassette transporter A1. Potential implications for determining the structure of nascent high density lipoprotein particles. J. Biol. Chem. 279: 41529-41536.
22. Sokoloff, L., and G. H. Rothblat. 1974. Sterol to phospholipid molar ratios of L cells with qualitative and quantitative variations of cellular sterol. Proc. Soc. Exp. Biol. Med. 146: 1166-1172.
23. Tall, A. R., V. Hogan, L. Askinazi, and D. M. Small. 1978. Interaction of plasma high density lipoproteins with dimyristoyllecithin multilamellar liposomes. Biochemistry. 17: 322-326.
24. Asztalos, B. F., P. S. Roheim, R. L. Milani, M. Lefevre, J. R. McNamara, K. V. Horvath, and E. J. Schaefer. 2000. Distribution of apoA-I-containing HDL subpopulations in patients with coronary heart disease. Arterioscler. Thromb. Vasc. Biol. 20: 2670-2676.
25. Favari, E., M. Lee, L. Calabresi, G. Franceschini, F. Zimetti, F. Bernini, and P. T. Kovanen. 2004. Depletion of pre-beta-high density lipoprotein by human chymase impairs ATP-binding cassette transporter A1- but not scavenger receptor class B type I-mediated lipid efflux to high density lipoprotein. J. Biol. Chem. 279: 9930-9936.
26. Nissen, S. E., T. Tsunoda, E. M. Tuzcu, P. Schoenhagen, C. J. Cooper, M. Yasin, G. M. Eaton, M. A. Lauer, W. S. Sheldon, C. L. Grines, et al. 2003. Effect of recombinant apoA-I Milano on coronary atherosclerosis in patients with acute coronary syndromes: a randomized controlled trial. J. Am. Med. Assoc. 290: 2292-2300.
27. Asztalos, B. F., M. Lefevre, T. A. Foster, R. Tulley, M. Windhauser, L. Wong, and P. S. Roheim. 1997. Normolipidemic subjects with low HDL cholesterol levels have altered HDL subpopulations. Arterioscler. Thromb. Vasc. Biol. 17: 1885-1893.
28. Fielding, C. J., and P. E. Fielding. 1995. Molecular physiology of reverse cholesterol transport. J. Lipid Res. 36: 211-228.
29. Kunitake, S. T., G. C. Chen, S. F. Kung, J. W. Schilling, D. A. Hardman, and J. P. Kane. 1990. Pre-beta high density lipoprotein. Unique disposition of apolipoprotein A-I increases susceptibility to proteolysis. Arteriosclerosis. 10: 25-30.
30. Huang, Y., A. von Eckardstein, S. Wu, and G. Assmann. 1995. Effects of the apolipoprotein E polymorphism on uptake and transfer of cell-derived cholesterol in plasma. J. Clin. Invest. 96: 2693-2701.
31. von Eckardstein, A., Y. Huang, S. Wu, H. Funke, G. Noseda, and G. Assmann. 1995. Reverse cholesterol transport in plasma of patients with different forms of familial HDL deficiency. Arterioscler. Thromb. Vasc. Biol. 15: 691-703.
32. Miida, T., Y. Nakamura, K. Inano, T. Matsuto, T. Yamaguchi, T. Tsuda, and M. Okada. 1996. Pre beta 1-high-density lipoprotein increases in coronary artery disease. Clin. Chem. 42: 1992-1995.
33. Asztalos, B. F., L. A. Cupples, S. Demissie, K. V. Horvath, C. E. Cox, M. C. Batista, and E. J. Schaefer. 2004. High-density lipoprotein subpopulation profile and coronary heart disease prevalence in male participants of the Framingham Offspring Study. Arterioscler. Thromb. Vasc. Biol. 24: 2181-2187.
34. Yancey, P. G., B. F. Asztalos, N. Stettler, D. Piccoli, D. L. Williams, M. A. Connelly, and G. H. Rothblat. 2004. SR-BI- and ABCA1-mediated cholesterol efflux to serum from patients with Alagille syndrome. J. Lipid Res. 45: 1724-1732.
35. Nanjee, M. N., C. J. Cooke, R. Garvin, F. Semeria, G. Lewis, W. L. Olszewski, and N. E. Miller. 2001. Intravenous apoA-I/lecithin discs increase pre-beta-HDL concentration in tissue fluid and stimulate reverse cholesterol transport in humans. J. Lipid Res. 42: 1586-1593.