Free/Total PSA (F/T ratio) kinetics in patients with clinically localized prostate cancer undergoing radical prostatectomy

Clinica Chimica Acta

Volumn 357, Issue 2, 2005, Pages 196-201

  Gregorakis, Alkiviades K ^a   Malovrouvas, Dimitrios ^b   Stefanakis, Stefanos ^b   Petraki, Konstantina ^b   Scorilas, Andreas ^a  

^a UNIVERSITY OF ATHENS   (Greece)

^b EVANGELISMOS HOSPITAL   (Greece)

Author keywords

Free PSA; Kallikreins; Prostate; Prostate cancer; Prostate specific antigen; PSA; Serine proteases; Tumor biomarkers

Indexed keywords

PROSTATE SPECIFIC ANTIGEN; TUMOR MARKER;

ADULT; AGED; ANTIGEN FUNCTION; ARTICLE; BIOACCUMULATION; BLOOD ANALYSIS; CANCER SURGERY; CLINICAL ARTICLE; COMPARTMENT MODEL; CONTROLLED STUDY; HUMAN; MALE; METABOLISM; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATECTOMY; PROTEIN BLOOD LEVEL; SURGICAL APPROACH; SURGICAL TECHNIQUE;

AGED; HUMANS; KINETICS; MALE; MIDDLE AGED; PROSTATE-SPECIFIC ANTIGEN; PROSTATECTOMY; PROSTATIC NEOPLASMS;

EID: 21244471790     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cccn.2005.03.027     Document Type: Article

References (28)

1. J.E. Oesterling Prostate specific antigen: a critical assessment of the most useful tumor marker for adenocarcinoma of the prostate J Urol 145 1991 907
2. M.C. Benson, I.S. Whang, and A. Pantuck Prostate specific antigen density: a means of distinguishing benign prostatic hypertrophy and prostate cancer J Urol 147 Pt. 2 1992 815
3. H.B. Carter, J.D. Pearson, and E.J. Metter Longitudinal evaluation of prostate specific antigen levels in men with and without prostate disease JAMA 267 1992 2215
4. J.E. Oesterling, W.H. Cooner, and S.J. Jacobsen Influence of patient age on the serum PSA concentration, an important clinical observation Urol Clin North Am 20 1993 671 680
5. H. Lilja, A. Christensson, and U. Dahlen Prostate-specific antigen in human serum occurs predominantly in complex with alpha-1-antichymotrypsin Clin Chem 37 1991 1618
6. U.H. Stenman, J. Leinonen, and H. Alfthan A complex between prostate-specific antigen and alpha-1-antichymotrypsin is the major form of prostate-specific antigen in serum of patients with prostatic cancer: assay of the complex improves clinical sensitivity for cancer Cancer Res 51 1991 222
7. T. Bjork, A. Bjartell, and P.A. Abrahamsson Alpha-1 antichymotrypsin production in PSA-producing cells is common in prostate cancer but rare in benign prostatic hyperplasia Urology 43 1994 427
8. W.J. Catalona Clinical utility of measurement of free and total prostate specific antigen (PSA): a review Prostate Suppl 7 1996 64 69
9. A. Scorilas, M. Plebani, S. Mazza, D. Basso, A.R. Soosaipillai, and D. Katsaros High sensitive immunoenzymatic detection of insulin-like growth factor 1 (IGF-1), human glandular kallikrein 2 (hK2) and total prostate specific antigen (PSA) for discriminating between prostate cancer and benign prostatic hyperplasia Prostate 54 2003 220 229
10. A. Magklara, A. Scorilas, C. Stephan, G. Kristiansen, S. Hauptmann, and K. Jung Decreased concentrations of prostate specific antigen (PSA) and human glandular kallikrein 2 (hK2) in malignant vs. non-malignant prostatic tissue Urology 56 2000 527 532
11. A. Magklara, A. Scorilas, W.J. Catalona, and E.P. Diamandis The combination of human glandular kallikrein and free prostate-specific antigen (PSA) enhances discrimination between prostate cancer and benign prostatic hyperplasia in patients with moderately increased total PSA Clin Chem 45 1999 1960 1966
12. D.L. Woodrum, M.K. Brawer, and A.W. Partin Interpretation of free prostate specific antigen clinical research studies for the detection of prostate cancer: a review J Urol 159 1 1998 5 12
13. T.A. Stamey, N. Yang, A.R. Hay, J.E. McNeal, F.S. Freiha, and E. Redwine Prostate-specific antigen as a serum marker for adenocarcinoma of the prostate N Engl J Med 317 1987 909 917
14. J.E. Oesterling, D.W. Chan, J.I. Epstein, A.W. Kimball Jr., D.J. Bruzek, and R.C. Rock Prostate-specific antigen in the preoperative and postoperative evaluation of localized prostatic cancer treated with radical prostatectomy J Urol 139 1988 766 772
15. C. Stephan, G.M. Yousef, A. Scorilas, K. Jung, M. Jung, and G. Kristiansen Quantitative analysis of kallikrein 15 gene expression in prostatic tissue J Urol 169 2003 361 364
16. T. Nakamura, A. Scorilas, C. Stephan, K. Jung, A.R. Soosaipillai, and E.P. Diamandis The usefulness of serum human kallikrein 11 for discriminating between prostate cancer and benign prostatic hyperplasia Cancer Res 63 2003 6543 6546
17. C. Stephan, G.M. Yousef, A. Scorilas, K. Jung, M. Jung, and G. Kristiansen Hepsin is highly over expressed in and a new candidate for a prognostic indicator in prostate cancer J Urol 171 2004 187 191
18. T.D. Richardson, K.J. Wojno, and L.W. Liang Serum half life determination of free prostate specific antigen J Urol 155 1996 698
19. A. Semjonow, F. Oberpenning, and W. Surdel PSA and radical prostatectomy: variation after manipulation of the prostate and consecutive elimination half-life of free and total PSA J Urol 155 1996 697
20. T.D. Richardson, K.J. Wojno, L.W. Liang, D.A. Giacherio, B.G. England, and W.H. Henricks Half-life determination of serum free prostate-specific antigen following radical retropubic prostatectomy Urology 48 6A Suppl. 1996 40 44
21. M. Lein, B. Brux, K. Jung, W. Henke, F. Koenig, and C. Stephan Elimination of serum free and total prostate-specific antigen after radical retropubic prostatectomy Eur J Clin Chem Clin Biochem 35 8 1997 591 595
22. T. Bjork, B. Ljungberg, T. Piironen, P.A. Abrahamsson, K. Pettersson, and A.T. Cockett Rapid exponential elimination of free prostate-specific antigen contrasts the slow, capacity-limited elimination of PSA complexed to alpha 1-antichymotrypsin from serum Urology 51 1 1998 57 62
23. E. Brandle, O. Hautmann, M. Bachem, K. Kleinschmidt, H.W. Gottfried, and A. Grunert Serum half-life time determination of free and total prostate-specific antigen following radical prostatectomy-a critical assessment Urology 53 4 1999 722 730
24. G. Birkenmeier, F. Struck, and R. Gebhardt Clearance mechanism of prostate specific antigen and its complexes with alpha2-macroglobulin and alpha1-antichymotrypsin J Urol 162 3 Pt 1 1999 (Sep) 897 901
25. A. Patel, F. Dorey, J. Franklin, and J.B. DeKernion Recurrence patterns after radical retropubic prostatectomy: clinical usefulness of prostate specific antigen doubling time and log slope prostate specific antigen J Urol 158 1997 1441 1445
26. D.W. Lin, J.L. Noteboom, and B.A. Blumenstein Serum percent free prostate-specific antigen in metastatic prostate cancer Urology 52 1998 366 371
27. K.J. Wojno, A.R. Vashi, and P.F. Schellhammer Percent free prostate-specific antigen value in men with recurrent prostate cancer after radical prostatectomy Urology 52 1998 474 478
28. A. Scorilas, H. Yu, A.R. Soosaipillai, A.K. Gregorakis, and E.P. Diamandis Comparison of the percent free prostate-specific antigen levels in the serum of healthy men and in men with recurrent prostate cancer after radical prostatectomy Clin Chim Acta 25 292(1-2) 2000 127 138