Effects of EGF and bFGF on irradiated parotid glands

Annals of Biomedical Engineering

Volumn 33, Issue 5, 2005, Pages 685-695

  Thula, Taili T ^a,c   Schultz, Gregory ^a   Tran Son Tay, Roger ^a   Batich, Christopher ^a,b  

^a UNIVERSITY OF FLORIDA   (United States)

^b J Crayton Pruitt Family Department of Biomedical Engineering   (United States)

^c NONE   (United States)

Author keywords

Apoptosis; bFGF; EGF; Microspheres; PLGA; Radiation; Salivary glands

Indexed keywords

APOPTOSIS; BASIC FIBROBLAST GROWTH FACTOR (BFGF); EPIDERMAL GROWTH FACTORS (EGF); MICROSPHERES; PLGA; SALIVARY GLANDS;

BIOMEDICAL ENGINEERING; CELL CULTURE; CELLS; DNA; GROWTH KINETICS; IRRADIATION; PROTEINS; RADIATION EFFECTS;

EPIDEMIOLOGY;

EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; RADIOPROTECTIVE AGENT;

ANIMAL; APOPTOSIS; ARTICLE; CELL CULTURE; CHEMISTRY; DELAYED RELEASE FORMULATION; DIFFUSION; DRUG EFFECT; IN VITRO STUDY; PAROTID GLAND; PARTICLE SIZE; PATHOLOGY; PATHOPHYSIOLOGY; RADIATION EXPOSURE; RADIATION INJURY; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS; CELLS, CULTURED; DELAYED-ACTION PREPARATIONS; DIFFUSION; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; PAROTID GLAND; PARTICLE SIZE; RADIATION INJURIES; RADIATION-PROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 21244466382     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10956-005-1853-z     Document Type: Article

References (44)

1. Abok, K., U. Brunk, B. Jung, and J. Ericsson. Morphologic and histochemical-studies on the differing radiosensitivity of ductular and acinar-cells of the rat submandibular-gland. Virchows Archiv B-Cell Pathol. Ind. Mol. Pathol. 45(4):443-460, 1984.
2. Bagesund, M., S. Richter, B. Agren, O. Ringden, and G. Dahllof. Scintigraphic study of the major salivary glands in pediatric bone marrow transplant recipients. Bone Marrow Transplant. 26(7):775-779, 2000.
3. Chailler, P., and D. Menard. Ontogeny of EGF receptors in the human gut. Frontiers Biosci. 4:d87-dl01, 1999.
4. Chao, K. S. C., J. O. Deasy, J. Markman, J. Haynie, C. A. Perez, J. A. Purdy, and D. A. Low. A prospective study of salivary function sparing in patients with head-and-neck cancers receiving intensity-modulated or three-dimensional radiation therapy: Initial results. Int. J. Radiat. Oncol. Biol. Phys. 49(4):907-916, 2001.
5. Christensen, M. E., H. S. Hansen, S. S. Poulsen, F. Bretlau, and E. Nexo. Immunohistochemical and quantitative changes in salivary EGF, amylase and haptocorrin following radiotherapy for oral cancer. Acta Oto-Laryngol. 116(1):137-143, 1996.
6. Cleland, J. L., E. Duenas, A. Daugherty, M. Marian, J. Yang, M. Wilson, A. C. Celniker, A. Shahzamani, V. Quarmby, H. Chu, V. Mukku, A. Mac, M. Roussakis, N. Gillette, B. Boyd, D. Yeung, D. Brooks, Y. Maa, C. Hsu, and A. J. S. Jones. Recombinant human growth hormone poly(lactic-co-glycolic acid) (PLGA) microspheres provide a long lasting effect. J. Control. Release 49(2-3): 193-205, 1997.
7. Cohen, J. E., C. Toulas, S. Monteil, B. Counderc, A. Maret, J. J. Bard, H. Prats, N. Daly-Schveitzer, and G. Favre. Radioresistance induced by the high molecular forms of the basic fibroblast growth factor is associated with an increased G (2) delay and a hyperphosphorylation of p34 (CDC2) in HeLa cells. Cancer Res. 57(7):1364-1370, 1997.
8. Cooper, J. S., K. Fu, J. Marks, and S. Silverman. Late effects of radiation-therapy in the head and neck region. Int. J. Radiat. Oncol. Biol. Phys. 31(5):1141-1164, 1995.
9. Cordewener, F. W., L. C. Dijkgraaf, J. L. Ong, C. M. Agarwal, G. Zardeneta, S. B. Milan, and J. P. Schmitz. Particulate retrieval of hydrolytically degraded poly(lactide- co-glycolide) polymers. J. Biomed. Mater. Res. 50(1):59-66, 2000.
10. Crotts, G., and T. G. Park. Stability and release of bovine serum albumin encapsulated within poly(D,L-lactide-co-glycolide) microparticles. J. Control. Release 44(2-3): 123-134, 1997.
11. Crotts, G., H. Sah, and T. G. Park. Adsorption determines in-vitro protein release rate from biodegradable microspheres: Quantitative analysis of surface area during degradation. J. Control. Release 47(1):101-111, 1997.
12. Eisbruch, A., R. K. Ten Haken, H. M. Kim, L. H. Marsh, and J. A. Ship. Dose, volume, and function relationships in parotid salivary glands following conformal and intensity-modulated irradiation of head and neck cancer. Int. J. Radiat. Oncol. Biol. Phys. 45(3):577-587, 1999.
13. Folkman, J., and K. Camphausen. Cancer - What does radiotherapy do to endothelial cells? Science 293(5528):227-228, 2001.
14. Franzen, L., U. Funegard, S. Sundstrom, H. Gustafsson, A. Danielsson, and R. Henriksson. Fractionated-irradiation and early changes in salivary-glands - different effects on potassium efflux, exocytotic amylase release and gland morphology. Lab. Invest. 64(2):279-283, 1991.
15. Franzen, L., H. Gustafsson, S. Sundstrom, M. Karlsson, B. Littbrand, and R. Henriksson. Fractionated-irradiation and late changes in rat parotid-gland - effects on the number of acinarcells, potassium efflux, and amylase secretion. Int. J. Radiat. Biol. 64(1):93-101, 1993.
16. Fuks, Z., R. S. Persaud, A. Alfieri, M. Mcloughlin, D. Ehleiter, J. L. Schwartz, A. P. Seddon, C. Cordoncardo, and A. Haimovitzfriedman. Basic fibroblast growth-factor protects endothelial-cells against radiation-induced programmed celldeath in vitro, and in vivo. Cancer Res. 54( 10):2582-2590, 1994.
17. Greenspan, D., and T. E. Daniels. Effectiveness of pilocarpine in postradiation xerostomia. Cancer 59(6): 1123-1125, 1987.
18. Gustafsson, H., L. Franzen, and R. Henriksson. Regeneration of parotid acinar-cells after high radiation-doses - A morphological-study in rat. Acta Oncol. 34(2): 193-197, 1995.
19. Haimovitzfriedman, A., I. Vlodavsky, A. Chaudhuri, L. Witte, and Z. Fuks. Autocrine effects of fibroblast growth-factor in repair of radiation-damage in endothelial-cells. Cancer Res. 51(10):2552-2558, 1991.
20. Haimovitzfriedman, A., Balaban, M. Mcloughlin, D. Ehleiter, J. Michaeli, I. Vlodavsky, and Z. Fuks. Protein-kinase-c mediates basic fibroblast growth-factor protection of endothelialcells against radiation-induced apoptosis. Cancer Research 54(10):2591-2597, 1994.
21. Hiramatsu, Y., H. Kagami, K. Horie, Y. Okazaki, T. Shigetomi, K. Hata, S. Kobayashi, and M. Ueda. Effects of basic fibroblast growth factor on cultured rat and human submandibular salivary gland cells. Arch. Oral Biol. 45(7):593-599, 2000.
22. Jha, N., H. Seikaly, T. McGaw, and L. Coulter. Submandibular salivary gland transfer prevents radiation- induced xerostomia. Int. J. Radiat. Oncol. Biol. Phys. 46(1):7-11, 2000.
23. Jung, M., F. G. Kern, T. J. Jorgensen, S.W. Mcleskey, O. C. Blair, and A. Dritschilo. Fibroblast growth factor-IV enhanced G (2) arrest and cell- survival following ionizing-radiation. Cancer Res. 54(19):5194-5197, 1994.
24. King, T. W., and C. W. Patrick. Development and in vitro characterization of vascular endothelial growth factor (VEGF)-loaded poly(DL-lactic-co- glycolic acid)/poly(ethylene glycol) microspheres using a solid encapsulation/single emulsion/solvent extraction technique. J. Biomed. Mater. Res. 51(3):383-390, 2000.
25. Nagler, R., Y. Marmary, P. C. Fox, B. J. Baum, R. Harei, and M. Chevion. Irradiation-induced damage to the salivary glands: The role of redox-active iron and copper. Radiat. Res. 147(4):468-476, 1997.
26. Nagler, R., Y. Marmary, E. Golan, and M. Chevion. Novel protection strategy against X-ray-induced damage to salivary glands. Radiat. Res. 149(3):271-276, 1998.
27. Nagler, R. M. The enigmatic mechanism of irradiation-induced damage to the major salivary glands. Oral Dis. 8(3): 141-146, 2002.
28. Nagler, R. M., B. J. Baum, and P. C. Fox. Acute effects of x-irradiation on the function of rat salivary- glands. Radiat. Res. 136(1):42-47, 1993.
29. O'Connell, A. C., C. D. Lillibridge, C. Y. Zheng, B. J. Baum, B. C. O'Connell, and I. S. Ambudkar. Gamma-irradiationinduced cell cycle arrest and cell death in a human submandibular gland cell line: Effect of E2F1 expression. J. Cell. Physiol. 177(2):264-273, 1998.
30. Okazaki, Y., H. Kagami, T. Hattori, S. Hishida, T. Shigetomi, and M. Ueda. Acceleration of rat salivary gland tissue repair by basic fibroblast growth factor. Arch. Oral Biol. 45(10):911-919, 2000.
31. Oxford, G. E., K. H. T. Nguyen, C. E. Alford, Y. Tanaka, and M. G. Humphreys-Beher. Elevated salivary EGF levels stimulated by periodontal surgery. J. Periodontol. 69(4):479-484, 1998.
32. Paris, F., Z. Fuks, A. Kang, P. Capodieci, G. Juan, D. Ehleiter, A. Haimovitz-Friedman, C. Cordon-cardo, and R. Kolesnick. Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. Science 293(5528):293-297, 2001.
33. Peter, B., M. Vanwaarde, A. Vissink, E. J. Sgravenmade, and A. W. T. Konings. Radiation-induced cell-proliferation in the parotid and submandibular glands of the rat. Radiat. Res. 140(2):257-265, 1994.
34. Peter, B., M. Vanwaarde, A. Vissink, E. J. Sgravenmade, and A. W. T. Konings. The role of secretory granules in radiation-induced dysfunction of rat salivary-glands. Radiat. Res. 141(2): 176-182, 1995.
35. Pistel, K. F., A. Breitenbach, R. Zange-Volland, and T. Kissel. Brush-like branched biodegradable polyesters, part III - Protein release from microspheres of poly(vinyl alcohol)-graftpoly(D,L-lactic-co-glycolic acid). J. Control. Release 73(1):7-20, 2001.
36. Purushotham, K. R., K. Offenmuller, A. T. Bui, T. Zolles, J. Blazsek, G.S. Schultz, and M. G. Humphreys -B eher. Absorption of epidermal growth factor occurs through the gastrointestinal tract and oral cavity in adult rats. Am. J. Physiol.-Gastrointest. Liver Physiol. 32(6):G867-G873, 1995.
37. Purushotham, K. R., T. Zelles, J. Blazsek, P. L. Wang, G. A. Paul, M. Kerr, and M. G. Humphreys-Beher. Effect of Egf on rat parotid-gland secretory function. Comp. Biochem. Physiol. C-Pharmacol. Toxicol. Endocrinol. 110(1):7-14, 1995.
38. Roesink, J. M., A. W. T. Konings, C. H. J. Terhaard, J. J. Battermann, H. H. Kampinga, and R. P. Coppes. Preservation of the rat parotid gland function after radiation by prophylactic pilocarpine treatment: Radiation dose dependency and compensatory mechanisms. Int. J. Radiat. Oncol. Biol. Phys. 45(2):483-489, 1999.
39. Sreebny, L. M., W. X. Zhu, S. S. Schwartz, and A. G. Meek. The preparation of an autologous saliva for use with patients undergoing therapeutic radiation for head and neck-cancer. J. Oral Maxillofac. Surg. 53(2): 131-139, 1995.
40. Stephens, L. C., G. K. King, L. J. Peters, K. K. Ang, T. E. Schultheiss, and J. H. Jardine. Acute and late radiation-injury in rhesus-monkey parotid-lands - Evidence of interphase celldeath. Am. J. Pathol. 124(3):469-478, 1986.
41. Stephens, L. C., T. E. Schultheiss, S. M. Small, K. K. Ang, and L. J. Peters. Response of parotid-gland organ-culture to radiation. Radiat. Res. 120(1): 140-153, 1989.
42. Stephens, L. C., and K. K. Ang. Is substance-P a mediator of radiation slaloadenitis. International Journal of Radiation Oncology Biology Physics 33(2):529-530, 1995.
43. Telbisz, A., A. L. Kovacs, and Z. Somosy. Influence of X-ray on the autophagic-lysosomal system in rat pancreatic acini. Micron 33(2): 143-151, 2002.
44. Zhu, G. Z., S. R. Mallery, and S. P. Schwendeman. Stabilization of proteins encapsulated in injectable poly (lactideco-glycolide). Nat. Biotechnol. 18(1):52-57, 2000.