SKI306X, an oriental herbal mixture, suppresses gastric leukotriene B 4 synthesis without causing mucosal injury and the diclofenac-induced gastric lesions

Life Sciences

Volumn 77, Issue 11, 2005, Pages 1181-1193

  Kim, Joo Hyon ^a   Rhee, Hae In ^a   Jung, In Ho ^a   Ryu, KeunHo ^a   Jung, Kiwon ^a   Han, Chang Kyun ^a   Kwak, Wie Jong ^a   Cho, Yong Baik ^a   Joo, Hee Jae ^b  

^a SK Chemicals   (South Korea)

^b Ajou University   (South Korea)

Author keywords

Gastric mucosa; Leukotriene; Prostaglandin; SKI 306X

Indexed keywords

CELECOXIB; CLEMATIS MANDSHURICA EXTRACT; CYCLOOXYGENASE 2 INHIBITOR; DICLOFENAC; ICOSANOID; LEUKOTRIENE; NONSTEROID ANTIINFLAMMATORY AGENT; PLANT EXTRACT; PROSTAGLANDIN E; PRUNELLA VULGARIS EXTRACT; SK 1306 X; TRICHOSANTHES KIRILOWII EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD; CONTROLLED STUDY; DRUG SAFETY; DRUG SPECIFICITY; DRUG TOLERABILITY; HISTOLOGY; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PROSTAGLANDIN SYNTHESIS; PROSTAGLANDIN SYNTHESIS INHIBITION; RAT; STOMACH EROSION; STOMACH HEMORRHAGE; STOMACH INJURY; STOMACH MUCOSA LESION; STOMACH ULCER;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DEPRESSION, CHEMICAL; DICLOFENAC; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; EICOSANOIDS; GASTRIC MUCOSA; LEUKOTRIENE B4; MALE; PEROXIDASE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PYRAZOLES; RATS; RATS, SPRAGUE-DAWLEY; STOMACH ULCER; SULFONAMIDES;

ANIMALIA;

EID: 21244452753     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2004.11.040     Document Type: Article

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